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Biology 3 Winter 2009 First Exam Name & SID 1A -3 pts. For each of the following elements state how many protons, neutrons and valence electrons are present in a single atom: Helium atomic number 2, atomic mass number 3 2 protons, 1 neuton, 2 valence electrons Chlorine, atomic number 17, atomic mass number 29 17 protons, 12 neutrons, 7 valence electrons 1B – 4 pts Briefly describe the difference between a polar covalent bond and an ionic bond. While both are polar, an ionic bond is when two atoms exchange one or more electrons in order to fill their outermost shell and stick together as a result of their opposite electrostatic charge. Polar covalent bonds represent unequally shared pairs of electrons with each atom contributing one electron to the shared pair, but since they are unequally shared there is a resulting partial charge to the molecule they form. 1C- 3pts What is the difference between a molecule and a compound? A molecule is any structure that consists of two or more atoms bonded together. A compound is any molecule with two or more elements in its structure 2A – 4 pts Define the following: Solute Material that is suspended by solvent in a solution Solvent the medium into which the solute(s) of a solution are suspended Hydrophobic Reactive with water Aqueous solution any solution that has water as its solvent 2B – 4 pts If the atomic mass number of C = 12, H = 1, and O = 16: What does a mole of methane (CH4) weigh? = 1x12 + 4x1 = 16 g How about a mole of ribose (C5H10O5)? = 5x12+ 10x1 + 5x16 = 150 g 2C – 4 pts Define the following: Diffusion the net passive movement of material from high to low concentration Osmosis the diffusion of water across a semi-permeable membrane (not if they do not properly define diffusion in the answer above they should not receive credit for using it in the definition of osmosis) 3 – 4 ptsWhat happens when a chemical reaction reaches equilibrium? Either 1) there is no net change in the [] of reactants & products or 2) the rate of the forward and reverse reaction are equal 4A – 4pts Sketch the products of the reaction that would join these two molecules making sure to show all products produced. What is this type of reaction called? What would the reverse reaction be called? HO OH hydrolysis HO HO OH Dehydration synthesis O OH +H20 4B – 4pts What is meant by tetravalence with respect to carbon? Why does this phenomenon make it especially suitable to form the backbone of biological molecules? Tetravalence refers to the presence of four valence electrons which means that carbon can form four covalent bonds. This allows it to link with other carbons to form the backbone of molecules while still having slots left for other functional groups to attach to 4C – 4 ptsLabel the following simple biological molecules: A = nucleotide, B = amino acid, C = fatty acid, D = simple sugar 4D – 5 pts. Now locate the following functional groups on any of the molecules and circle and label them (note you only need to circle and label each group once). Methyl group, hydroxyl group, phosphate group, carboxyl group, amino group -I’m confident you guys can figure this out Name & SID 5A – 2pts What makes simple sugars hydrophilic? They are full of hydroxyl groups which have polar covalent bonds between the oxygen and the hydrogen making the molecule as a whole polar and reactive with water 5B – 2ptsWhat kind of carbohydrates are starch and glycogen? They are both polysaccharides 5C – 2pts. What causes starch and glycogen to coil? The same hydroxyl groups that make starch and glycogen hydrophilic also readily form hydrogen bonds with each other. Because these bonds are relatively weak, they are only sufficient to gently coil the molecule via the interaction of non-neighbor monomers. 6A – 3pts Briefly explain the difference between a saturated, mono-unsaturated, and poly-unsaturated fat. While all three are triglycerides, they differ in the relative number of carbon to carbon double bonds in their fatty acid tails. Saturated fats have no carbon to carbon double bonds and are unkinked. Monounsaturated fats have a single carbon to carbon double bond in each of their fatty acid tails and thus there is a single kink in each. Polyunsaturated fats have several carbon to carbon double bonds in their fatty acids tails and as a result they are highly kinked 6B – 2ptsWhat property do phospholipids share with triglycerides? How do they differ Both have two fatty acid tails joined to a glycerol backbone and as such will interact with hydrophobic substances. Phospholipids differ in having a charged polar head on the 3rd slot of the glycerol backbone as opposed to another fatty acid tail (found in triglycerides). This aligns on the opposite side of the glycerol backbone and allows phospolipids to interact with hydrophilic substances as well. 7A – 6 pts Briefly describe (not list) the four possible levels of protein structure. Primary – the specific sequence of amino acids of a polypeptide Secondary – the coiling or sheeting of the polypeptide due to hydrogen bonds between different regions of the backbone Tertiary – the folding of the polypeptide due to interaction of the R groups of different amino acids Quaternary – two or more polypeptides form the final functional protein 7B – 2 pts. With respect to proteins, what is meant by final conformation and denatured? Final conformation refers to the final functional shape of a protein after it has attained all the levels of structure. Denatured refers to the loss of structure and as a result function of a protein 8A – 3pts. What are the three basic components of a nucleotide? A phosphate, a five carbon sugar, and a nitrogenous base 8B – 2pts How arenucleotides arranged to form polymers (ie what pattern do they take) The basic pattern of a nucleic acid is an alternating backbone of phosphates and sugars with nitrogenous bases sticking up from each sugar 8C – 2 pts. What are purines and pyrimidines and how do they differ? They are both nitrogenous bases found in nucleic acids. Pruines consist of double ringed structures while pyrimidines have a single ring structure 9A – 3pts What are the three basic components found in any cell? A plasma (cell) membrane Genetic material Cytoplasm 9B – 6 pts. What are the two basic types of cells and how do they differ from each other? The two basic types of cells are prokaryotes and eukaryotes. Prokaryotes lack a true nucleus and membranous organelles, eukaryotes have both these features. 10A – 4pts Label the following diagram depicting different mechanisms of transport across the cell membrane. Be as specific as possible A = simple diffusion, B = facilitated diffusion via a channel protein, C = Facilitated diffusion via a carrier protein, D = active transport via a carrier protein. Name & SID 10B – 2pts.What is the nuclear envelope? What is it primarily made of? The nuclear envelope is the double membrane that surrounds the nucleus of an eukaryotic cell. It is made principally of phospholipids 10C 2 pts What is chromatin and where would you find it? Chromatin is 50% protein and 50% nucleic acid and it would be found within the nucleus of an eukaryotic cell 10D – 5 pts. Briefly describe the structure and function of the following organelles: Rough endoplasmic reticulum Structure: channels of membranous tubes with ribosomes attached to it Function: internal cell transport and protein synthesis Smooth endoplasmic reticulum Structure: channels of membranous tubes with no ribosomes attached to it Function: internal cell transport and lipid synthesis Vesicle Structure: small membranous sac Function: internal cell transport, storage, endo/exocytosis Golgi body Structure: flattened stack of membranous sacs Function: receiving, shipping, processing and storage of biological molecules What cellular system are all these a part of? The endo or cytomembrane system 10E – 3 pts Ribosomes What is a ribosome made of? Ribosomal RNA What function does it serve in a cell? It is a workbench on which proteins are assembled Would you find it in a prokaryote or eukaryote? Both 10F – 3ps. What are the cristae & matrix and what organelle would you find them in? They are both found in the mitochondrion Cristae = the infoldings of the inner membrane that dramatically increase surface area Matrix = cytoplasm like material found within the inner membrane 10G – 3 pts What are the stroma & grana and what organelle would you find them in? They are both found in the chloroplast stroma = cytoplasm like material found within the inner membrane grans = stacks of thylakoids formed by the infolding of the inner membrane