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Science Pacing Resource Companion Biology Quarter 3 Unit 1 Unit #1: Cellular Reproduction Explain the processes (i.e., mitosis and meiosis) by which new cells are formed from existing cells and how in multicellular organisms groups of cells cooperate to perform essential functions within the organisms. Explain the cellular processes that occur to generate natural genetic variations between parents and offspring (B.6.1, B.6.2, B.6.3, B.6.4, B.6.5). B.6.1 Describe the process of mitosis and explain that this process ordinarily results in daughter cells with a genetic make-up identical to the parent cells. SWBAT: Diagram the stages of mitosis and explain that daughter cells are identical to parent cells. B.6.2 Understand that most cells of a multicellular organism contain the same genes but develop from a single cell (e.g., a fertilized egg) in different ways due to differential gene expression. SWBAT: Explain how differentiation comes about from the development of a single cell. B.6.3 Explain that in multicellular organisms the zygote produced during fertilization undergoes a series of cell divisions that lead to clusters of cells that go on to specialize and become the organism’s tissues and organs. SWBAT: Describe how a zygote divides to become a multicellular organisms and connect to tissues and organs. B.6.4 Describe and model the process of meiosis and explain the relationship between the genetic make-up of the parent cell and the daughter cells (i.e., gametes). SWBAT: Diagram the stages of meiosis and explain that daughter cells are different from parent cells. B.6.5 Explain how in sexual reproduction that crossing over, independent assortment and random fertilization result in offspring that are genetically different from the parents. SWBAT: Describe the connection between crossing over in meiosis and the many variations between parents and offspring. GLENCOE “BIOLOGY” ACTIVITIES AND RESOURCES: WEB-BASED RESOURCES: Chapter 9 http://www.johnkyrk.com/mitosis.html Mitosis Diagram pg. 249 http://www.neok12.com/Cell-Division.htm Data Analysis Lab (Microtubules) pg. 251 http://www.pbs.org/wgbh/nova/body/how-cells-divide.html Mitosis in Yeast Lab pg. 259 http://www.cellsalive.com/mitosis.htm Chapter 10 Meiosis Diagram pg. 273 and pg. 275 Crossing Over pg. 272 Data Analysis Lab (Motor Porteins Affect Cell Division) pg. 274 Punnett Squares pg. 280-282 Punnett Square Mini-Lab pg. 281 Phenotype & Genotype Lab pg. 287 Indianapolis Public Schools Curriculum and Instruction Science Pacing Resource Companion Biology Quarter 3 Unit 2 Unit #2 Molecular Basis of Heredity Describe the basic structure of DNA and how this structure enables DNA to function as the hereditary molecule that directs the production of RNA and proteins. Understand that proteins largely determine the traits of an organism (B.5.1, B.5.2, B.5.3, B.5.4, B.5.5, B.5.6). B.5.1 Describe the relationship between chromosomes and DNA along with their basic structure and function. SWBAT: Explain how DNA make up chromosomes. Draw and label a chromosome. B.5.2 Describe how hereditary information passed from parents to offspring is encoded in the regions of DNA molecules called genes. SWBAT: Compare how genes affect heredity. B.5.3 Describe the process by which DNA directs the production of protein within a cell. SWBAT: Produce a protein from a gene segment. B.5.5 Understand that proteins are responsible for the observable traits of an organism and for most of the functions within an organism. SWBAT: Name two proteins that are responsible for traits. B.5.4 Explain how the unique shape and activity of each protein is determined by the sequence of its amino acids. SWBAT: Explain what happens when we destroy the shape of a protein. Name and explain one disease caused by proteins altered shape. B.5.6 Recognize that traits can be structural, physiological or behavioral and can include readily observable characteristics at the organismal level or less recognizable features at the molecular and cellular level. SWBAT: Name two traits, one observable and one non-observable. GLENCOE “BIOLOGY” ACTIVITIES AND RESOURCES: WEB-BASED RESOURCES: Chapter 12 http://www.wiley.com/college/boyer/0470003790/animations/ DNA Structure pg. 329, pg. 331 translation/translation.htm DNA Structure Lab pg. 331 http://www.gla.ac.uk/t4/~vet/files/teaching/CAL/biomolecular /module1.htm Chromsome Structures pg. 332 http://www.biotechnologyonline.gov.au/popups/int_transcripti DNA Replication pg. 333-334 on.html Central Dogma pg. 336 http://www.wiley.com/college/test/0471787159/biology_basic Transcriptional and Translation pg. 338-340 s/animations/fromGeneToProtein.swf Mutations pg. 346 http://learn.genetics.utah.edu/content/molecules/transcribe/ DNA Extraction Lab pg. 351 Indianapolis Public Schools Curriculum and Instruction Science Pacing Resource Companion Biology Quarter 3 Unit 3 Unit #3: Genetics Explain how the genetic information from parents determines the unique characteristics of their offspring (B.7.1, B.7.2, B.7.3, B.7.4, B.7.5). B.7.1 Distinguish between dominant and recessive alleles and determine the phenotype that would result from the different possible combinations of alleles in an offspring. SWBAT: Predict a phenotype from a give genotype. B.7.3 Determine the likelihood of the appearance of a specific trait in an offspring given the genetic make-up of the parents. SWBAT: Make a Punnett square and predict genotypes and phenotypes of offspring. B.7.2 Describe dominant, recessive, co-dominant, sex-linked, incompletely dominant, multiply allelic and polygenic traits and illustrate their inheritance patterns over multiple generations. SWBAT: Compare and contrast sex-linked incomplete and co-dominant traits. GLENCOE “BIOLOGY” ACTIVITIES AND RESOURCES: WEB-BASED RESOURCES: Chapter 11 http://scienceprimer.com/punnett-square-calculator Complex Inheritance and Humanity Heredity Pedigrees pg. http://learn.genetics.utah.edu/content/labs/pcr/ 299 http://education-portal.com/academy/lesson/pedigree-analysis Incomplete & Codominance pg. 302 – 303 in-human-genetics-tutorial.html#lesson Multiple Alleles (Sex Linked) pg. 304 – 309 https://www.youtube.com/watch?v=fQvER3MyI2c Data Analysis Lab (Sickle Cell) pg. 303 http://www.sumanasinc.com/webcontent/animations/content/ Nondisjunction & Down Syndrome pg. 313 mistakesmeiosis/mistakesmeiosis.html Coin Toss Baby Lab pg. 317 https://www.youtube.com/watch?v=EA0qxhR2oOk Chapter 13 Applied Genetics (Genes & Biotechnology) pg. 360 DNA Fingerprinting pg. 381 Indianapolis Public Schools Curriculum and Instruction