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Lymphocyte Typing
Assessment of the immune system
The immune system consists of a series of organs, tissues
and cells widely distributed throughout the entire body.
These components are interconnected by blood and
lymph vessels, constituting a single well-communicated
system.
The response mechanisms of the immune system are the
innate or non-adaptive immunity (the natural killer cells, for
example) and the acquired or specific immunity (such as
the T and B lymphocytes). The cells that make up the
immune system have very diverse –even opposing, at
times– functions (such as the helper and the suppressor
lymphocytes), and the interaction between them allows the
existence of a state of self-regulated balance.
Assessment of the immune system
In the majority of diseases, whether acute or chronic, an
alteration of the immune system is detected, although it is
in the chronic diseases, which are
much more complex, where an
exhaustive analysis of the state of
the immune system is important,
for an optimal selection of
treatment and monitoring. The
alteration of the immune system is
associated with an increased
probability of developing infectious, autoimmune,
inflammatory diseases and also cancer.
The lymphocyte typing profiles provide an image of the
state of the immune system of the patient at a given
moment. Therefore, they are a useful tool for the diagnosis
and monitoring of the evolution of the patient to the
treatment.
The serological profile allows detecting the infectious
etiology of the alterations of the immune system,
identifying triggering or aggravating factors of diseases.
The protein profiles make possible a complementary
evaluation of the immune, inflammatory and also
nutritional state of the patient.
Immune system assessment profiles
The following profiles can be requested:
PE-LIN basic lymphocyte typing
Analysis of:
Leucocytes, natural killer cells, lymphocytes, T
lymphocytes, T4 lymphocytes, T8 lymphocytes,
T4/T8 ratio, B lymphocytes, activated T
lymphocytes,
cytotoxic
T8
lymphocytes,
suppressor T8 lymphocytes, T8c/T8s quotient,
regulator T4 lymphocytes
ILMISER serological profile
Analysis of:
Cytomegalovirus (IgG and IgM), varicella zoster
virus (IgG and IgM), Epstein Barr virus (EBNA,
VCA and EA) and herpes virus (HS1V-IgM,
HS1V-IgG, HS2V-IgM and HS2V-IgG)
LIN-3IDI expanded lymphocyte typing profile
Analysis of:
PE-LIN + ILMISER
ILMIPRO basic protein profile
Analysis of:
IgG, IgM, IgA, Alpha-1-glycoprotein acid
(Orosomucoid),
Haptoglobin,
ultrasensitive
quantitative PCR, soluble IL-2 receptor
PROTEICO expanded protein profile
Analysis of:
ILMIPRO plus analysis of the C3 complement, C4
complement, prealbumin and ferritin
INTERLEU Interleukin profile INTERLEU
Analysis of:
Th1 – cellular response (IFN-Ɣ, IL-2 and FNT-α)
+ Th2 – humoral response (IL-4, IL-6 and IL-10)
Indications
The immune system assessment is especially indicated
for:
Persons who want to proactively manage their health
The interleukin profile provides information on the
principal means of communication among the immune and
inflammatory cells, given that the interleukins initiate the
inflammatory response and define the magnitude and
nature of the immune response.
Date of revision:
24-07-2013
The assessment of the different components of the
immune system makes it possible to analyze its strength
and our state of health.
Monitoring of infectious, autoimmune, inflammatory
and cancerous processes
Monitoring of chronic pathologies
Monitoring of certain clinical treatments
Requirements
Sample: total blood EDTA and/or serum, depending on
the profile (consult). Fasting of 4 hours.
Josep Argemí 13
08950 Esplugues de Llobregat
T 93 470 56 56 F 93 473 28 55
Email [email protected] www.labco.es