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Lecture 3 Cell theory By: Saba Nazeih نظام المحاضرات االلكتروني • What Is a Cell? • Living things are constructed of cells and can be unicellular (one cell) or multicellular (many cells). • Limits on Cell Size • Cells size is limited because cells must be able to exchange materials with their surroundings. In other words, surface area relative to the volume decreases as size of cell increases, and this limits the size of cells. نظام المحاضرات االلكتروني • The CELL THEORY, or cell doctrine, states that all organisms are composed of similar units of organization, called cells. The concept was formally articulated in 1839 by Schleiden & Schwann and has remained as the foundation of modern biology. The idea predates other great paradigms of biology including Darwin's theory of evolution (1859), Mendel's laws of inheritance (1865), and the establishment of comparative biochemistry (1940). Ultrastructural research and modern molecular biology have added many tenets to the cell theory, but it remains as the preeminent theory of biology. The Cell Theory is to Biology as Atomic Theory is to Physics نظام المحاضرات االلكتروني • He summarized his observations into three conclusions about cells: 1) The cell is the unit of structure, physiology, and organization in living things. 2) The cell retains a dual existence as a distinct entity and a building block in the construction of organisms. 3) Cells form by free-cell formation, similar to the formation of crystals (spontaneous generation). نظام المحاضرات االلكتروني • The modern tenets of the Cell Theory include: 1. All known living things are made up of cells. 2. The cell is structural & functional unit of all living things. 3. All cells come from pre-existing cells by division. (Spontaneous Generation does not occur). 4. Cells contain hereditary information which is passed from cell to cell during cell division. 5. All cells are basically the same in chemical composition. 6. All energy flow (metabolism & biochemistry) of life occurs within cells. نظام المحاضرات االلكتروني