Download BIOL 1308

Course
Prefix
Course
Number
Title
SCH
Component Area
TCCCM
BIOL
1308
Biology for Non-Science Majors I
3
Life and Physical Science
BIOL 1308
(A)
I.
Course Description:
This course introduces the student to the nature of science and the application of science to
contemporary issues. Content includes the chemistry of life, the cell, genetics and mechanisms of
evolution.
II.
Course Delivery Method:
Face to Face
III.
Required Textbooks/Resources:
Campbell Biology (Concepts and Connections), 7th Ed., Campbell and Reece,
ISBN: 9780321696816
IV.
Student Learning Outcomes:
Upon completion of this course student will be able to•
•
•
•
•
•
•
V.
Describe the levels of biological organization and properties of life
Define the chemical basis of life and the and the molecules necessary for life
Compare prokaryotic and eukaryotic cells
Discuss photosynthesis and cellular respiration
Discuss the flow of genetic information
Explain why cell division is essential for prokaryotic and eukaryotic life
Discuss the applications of recombinant DNA technology and genetic engineering
Course Outline:
The following subject matter is covered through this course:
1.
2.
3.
4.
5.
6.
7.
The Scientific Study of Life
The Chemical Basis of Life
The Molecules of Cells
A Tour of the Cell
The Working Cell
Photosynthesis
The Cellular Basis of Reproduction and Inheritance
8.
9.
10.
11.
VI.
Patterns of Inheritance
Molecular Biology of the Gene
Genes are Controlled
DNA Technology and Genomics
Methods of Evaluation:
• Lecture Exams 3 at 100 points each
• Group Presentation at 100 points
• Final Exam at 100 points
(B)
Exams will cover the materials shown in the course outline above. They will include multiplechoice and essay/short answer items which cover the student learning outcomes. The group
poster presentation will be on a topic selected by students and approved by the instructor. The
topic will involve a controversial issue in science involving the current course content.
(C)
All chapters in required textbooks are mandatory readings.
(D)
Course Outline:
Topic
Introduction
The Chemical basis of Life
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Summary
Historical events in biology
Properties of life
Levels of biological organization
Emergent properties of life
Prokaryotic and eukaryotic cells
Dynamics of nutrients and energy in an ecosystem.
Domains of life
Process of natural selection
Quantitative and qualitative data
Inductive and deductive reasoning
Scientific theory and a hypothesis
Impacts of evolution
Importance of chemical elements
Formation of compounds.
Describe the structure of an atom
I ionic, hydrogen, and covalent bonds
Chemical reaction and explain how it changes the composition
of matter
The molecules of cells
The tour of the cell
The working cell
How Cells Harvest
Chemical Energy
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Photosynthesis: Using
light to make food
•
•
•
•
•
The Cellular Basis of
Reproduction and
•
•
•
•
•
•
Life-supporting properties of water
pH scale and the formation of acid and base solutions
Importance of carbon to life
Formation of large molecules from a small set of molecules
Importance of carbohydrates, lipids, nucleic acids, and
proteins to cells and life
Evolution of lactose tolerance
Importance of microscopes in understanding cell structure
and function
Parts of cell theory
Structures of prokaryotic and eukaryotic cells
Structure and functions of cell membranes
Structures of plant and animal cells
Endosymbiotic hypothesis
Functional categories of organelles
Fluid mosaic structure of cell membranes
Diverse functions of membrane proteins
Diffusion and osmosis
Active and passive transport
Exocytosis, endocytosis, phagocytosis, pinocytosis, and
receptor-mediated endocytosis
ATP functions as an energy shuttle
Processes and locations of cellular respiration and
photosynthesis
Chemical equation for cellular respiration
Rereactants, products, and energy yields of cellular
respiration, alcohol and lactic acid fermentation
Aerobic and anaerobic processes
Carbohydrates, fats, and proteins as fuel for cellular
respiration
Autotrophs and heterotrophs and their interdependence
Structure of chloroplasts and their location in a leaf
Reactants and products of the light reactions and the Calvin
cycle
Properties and functions of the different photosynthetic
pigments
Electron transport chain and chemiosmosis to generate ATP,
NADPH, and oxygen in the light reactions
Calvin cycle
C3, C4, and CAM plants
Greenhouse effect
Ozone layer
Parent-offspring relationship
Importance of cell division in life
Inheritance
Patterns of Inheritance
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Molecular biology of the
cell
•
•
•
•
•
•
•
•
•
•
•
•
•
•
How Genes Are Controlled •
•
•
•
•
•
•
•
Structure of prokaryotic and eukaryotic chromosomes
Stages of the cell cycle
Phases, events, and importance of mitosis
Cell division and cancer
Importance of sexual reproduction in life
Genetic variation and its importance
Causes and symptoms of Down syndrome
Consequences of abnormal numbers of sex chromosomes
Formation of new species due to error in cell division
Types of chromosomal changes
Pangenesis theory and the blending hypothesis
Genetic relationships between homologous chromosomes
Importance of family pedigrees to help determine the
inheritance of many human traits
Inheritance of recessive and dominant disorders
Advantages, and disadvantages of fetal testing
Inheritance patterns of incomplete dominance, multiple
alleles, codominance, pleiotropy, and polygenic inheritance
Adaptation of the Sickle-cell allele in certain human
population
Human skin coloration and polygenic inheritance
Chromosome theory of inheritance
Patterns of sex-linked inheritance
Y chromosome to trace human ancestry
DNA was life’s genetic material.
Structures of DNA and RNA
Process of DNA replication
Processing of RNA before leaving the nucleus
Structure and function of ribosome
Overall process of transcription and translation
Major types of mutations, causes of mutations, and potential
consequences
Processes that contribute to the emergence of viral disease
Structure of viroids and prions
Processes of transformation, transduction, and conjugation.
Regulatory mechanisms of the lac operon, trp operon, and
operons using activators
Selective gene
DNA packaging into chromosomes
Process and significance of alternative DNA splicing
Significance of miRNA molecules.
mRNA breakdown, initiation of translation, protein activation,
and protein breakdown regulate gene expression
DNA microarrays to study gene activity and treat disease
Signal transduction pathways
DNA Technology and
Genomics
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Cell-signaling systems
Practical applications of reproductive cloning
Development of cancers
Use of plasmids and restriction enzymes in gene cloning
Construction of cDNA and genomic libraries
Use of nucleic acid probe to identify a specific
DNA technology has helped to produce insulin, growth
hormone, and vaccines
Importance of genetically modified organisms(GMOs)
Benefits and risks of gene therapy in humans
Describe the basic steps of DNA profiling
Gel electrophoresis to sort DNA and proteins
Mapping of the human genome
Genomics and proteomics
Significance of genomics to the study of evolutionary
Justification:
This course fulfills the Life and Physical Science Foundation Component Area requirement in the
Core Curriculum. It addresses the Core Objectives by requiring critical thinking, oral and written
communication, empirical and quantitative skills, and teamwork. This course introduces the
student to the nature of science and the application of science to contemporary issues. Content
includes the chemistry of life, the cell, genetics and mechanisms of evolution.
Next is the full course syllabus for the class.
Course Prefix
BIOL
Course Number
1308
Title
Biology for non-Science
Majors I
SCH
3
Component Area TCCCNS
Life and Physical
BIOL
Science
1308
Suggested times: TR 4:00p-5:15p/MW 4:00p-5:15p; Limit 30. Offered every Fall Semester.
(A)
I.
Course Description: This course introduces the student to the nature of science
and the application of science to contemporary issues. Content includes the
chemistry of life, the cell, genetics and mechanisms of evolution.
II.
Course Delivery Method: Face-to-Face
llI.
Required Textbooks/Resources: Campbell Biology (Concepts and
Connections), 7th Ed., Campbell and Reece, ISBN: 9780321696816
IV.
Student Learner Outcomes:
Upon completion of this course student will be able to• Describe the levels of biological organization and properties of life
• Define the chemical basis of life and the and the molecules necessary
for life
• Compare prokaryotic and eukaryotic cells
• Discuss photosynthesis and cellular respiration
• Discuss the flow of genetic information
• Explain why cell division is essential for prokaryotic and eukaryotic life
• Discuss the applications of recombinant DNA technology and genetic
engineering
V.
Course Outline:
Week-1
Introduction: History of Biology (handout); The Scientific Study of Life (Ch1)
Week-2
The Chemical Basis of Life (Ch2)
Week-3
The Molecules of Cells (Ch3)
Exam-1
Week-4
A Tour of the Cell (Ch4)
Week-5
The Working Cell (Ch5)
Week-6
Photosynthesis: Using Light to Make Food (Ch7)
Exam-2
Week-7
How Cells Harvest Chemical Energy (Ch6)
Week-8&9
The Cellular Basis of Reproduction and Inheritance (Ch8)
Week-10&11
Patterns of Inheritance (Ch9)
Exam-3
Week-12&13
Molecular Biology of the Gene (Ch10)
Week-14
How Genes Are Controlled (Ch11)
Week-15&16
DNA Technology and Genomics (Ch12)
Reviews
Final Exam
VI.
Methods of Evaluation:
Lecture exams (3X100)
points
Group presentation
points
Final exam
points
_________________
….
300
…..
100
….
100
Total 500
Points
Grading Scale
>= 90% = A
>= 80% - < 90% = B
>= 70% - < 80% = C
>= 60%- < 70% = D
< 60 %= F
(B)
Exams will cover the materials shown in the course outline above. They will
include multiple-choice and essay/short answer items which cover the student learning
outcomes. The group poster presentation will be on a topic selected by students and
approved by the instructor. The topic will involve a controversial issue in science
involving the current course content.
(C)
Required reading will be the chapters in the textbook.
(D)
Each lecture will cover the items shown in the topic outline above. Two class
periods are generally required to cover a topic.
Topic
Introduction
The Chemical basis of
Life
The molecules of cells
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
The tour of the cell
•
•
•
•
•
•
•
•
•
Summary
Historical events in biology
Properties of life
Levels of biological organization
Emergent properties of life
Prokaryotic and eukaryotic cells
Dynamics of nutrients and energy in an ecosystem.
Domains of life
Process of natural selection
Quantitative and qualitative data
Inductive and deductive reasoning
Scientific theory and a hypothesis
Impacts of evolution
Importance of chemical elements
Formation of compounds.
Describe the structure of an atom
I ionic, hydrogen, and covalent bonds
Chemical reaction and explain how it changes the
composition of matter
Life-supporting properties of water
pH scale and the formation of acid and base solutions
Importance of carbon to life
Formation of large molecules from a small set of
molecules
Importance of carbohydrates, lipids, nucleic acids, and
proteins to cells and life
Evolution of lactose tolerance
Importance of microscopes in understanding cell
structure and function
Parts of cell theory
Structures of prokaryotic and eukaryotic cells
Structure and functions of cell membranes
Structures of plant and animal cells
Endosymbiotic hypothesis
Functional categories of organelles
The working cell
How Cells Harvest
Chemical Energy
•
•
•
•
•
•
•
•
•
•
•
Photosynthesis: Using
light to make food
•
•
•
•
•
The Cellular Basis of
Reproduction and
Inheritance
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
•
Fluid mosaic structure of cell membranes
Diverse functions of membrane proteins
Diffusion and osmosis
Active and passive transport
Exocytosis, endocytosis, phagocytosis, pinocytosis, and
receptor-mediated endocytosis
ATP functions as an energy shuttle
Processes and locations of cellular respiration and
photosynthesis
Chemical equation for cellular respiration
Rereactants, products, and energy yields of cellular
respiration, alcohol and lactic acid fermentation
Aerobic and anaerobic processes
Carbohydrates, fats, and proteins as fuel for cellular
respiration
Autotrophs and heterotrophs and their
interdependence
Structure of chloroplasts and their location in a leaf
Reactants and products of the light reactions and the
Calvin cycle
Properties and functions of the different photosynthetic
pigments
Electron transport chain and chemiosmosis to generate
ATP, NADPH, and oxygen in the light reactions
Calvin cycle
C3, C4, and CAM plants
Greenhouse effect
Ozone layer
Parent-offspring relationship
Importance of cell division in life
Structure of prokaryotic and eukaryotic chromosomes
Stages of the cell cycle
Phases, events, and importance of mitosis
Cell division and cancer
Importance of sexual reproduction in life
Genetic variation and its importance
Causes and symptoms of Down syndrome
Consequences of abnormal numbers of sex
chromosomes
Formation of new species due to error in cell division
Types of chromosomal changes
Patterns of Inheritance
•
•
•
•
•
•
•
Molecular biology of
the cell
•
•
•
•
•
•
•
•
•
•
•
•
•
•
How Genes Are
Controlled
•
•
•
•
•
•
•
•
•
Pangenesis theory and the blending hypothesis
Genetic relationships between homologous
chromosomes
Importance of family pedigrees to help determine the
inheritance of many human traits
Inheritance of recessive and dominant disorders
Advantages, and disadvantages of fetal testing
Inheritance patterns of incomplete dominance, multiple
alleles, codominance, pleiotropy, and polygenic
inheritance
Adaptation of the Sickle-cell allele in certain human
population
Human skin coloration and polygenic inheritance
Chromosome theory of inheritance
Patterns of sex-linked inheritance
Y chromosome to trace human ancestry
DNA was life’s genetic material.
Structures of DNA and RNA
Process of DNA replication
Processing of RNA before leaving the nucleus
Structure and function of ribosome
Overall process of transcription and translation
Major types of mutations, causes of mutations, and
potential consequences
Processes that contribute to the emergence of viral
disease
Structure of viroids and prions
Processes of transformation, transduction, and
conjugation.
Regulatory mechanisms of the lac operon, trp operon,
and operons using activators
Selective gene
DNA packaging into chromosomes
Process and significance of alternative DNA splicing
Significance of miRNA molecules.
mRNA breakdown, initiation of translation, protein
activation, and protein breakdown regulate gene
expression
DNA microarrays to study gene activity and treat disease
Signal transduction pathways
Cell-signaling systems
DNA Technology and
Genomics
•
•
•
•
•
•
Practical applications of reproductive cloning
Development of cancers
Use of plasmids and restriction enzymes in gene cloning
Construction of cDNA and genomic libraries
Use of nucleic acid probe to identify a specific
DNA technology has helped to produce insulin, growth
hormone, and vaccines
Importance of genetically modified organisms(GMOs)
Benefits and risks of gene therapy in humans
Describe the basic steps of DNA profiling
Gel electrophoresis to sort DNA and proteins
Mapping of the human genome
Genomics and proteomics
Significance of genomics to the study of evolutionary
•
•
•
•
•
•
•
This course fulfills the Life and Physical Science Foundation Component Area
requirement in the Core Curriculum. It addresses the Core Objectives by requiring
critical thinking, oral and written communication, empirical and quantitative skills, and
teamwork. This course introduces the student to the nature of science and the
application of science to contemporary issues. Content includes the chemistry of life,
the cell, genetics and mechanisms of evolution.
Activity
Group Presentation
•
•
•
•
Core Objective
Critical Thinking Skills
Teamwork
Communication Skills
Empirical and
Quantitative Skills
Students will work in
groups to develop a poster
which illustrates a current
issue in science. Producing
the poster will involve all
of the core objective
areas. In producing the
poster students will be
doing an activity like
scientists produce for
scientific meetings.