Download Cystic Fibrosis

Cystic Fibrosis
IVFAustralia’s Network of Care
Clinic
Consultation & Monitoring
IVFAustralia’s guide to your screening
Consulting Rooms
Bondi Jn
Burwood
Castle Hill
16th Floor Westfield Tower 2, 500 Oxford St
Suite 18 Level 7, 74-76 Burwood
Suite 4, 15-17 Terminus St
8305 9800
8346 6840
9894 4419
Dee Why
Gosford
Greenwich
Level 3, 834 Pittwater Road
Level 2 Suite 24, 207 North Albany St
Level 2, 176 Pacific Highway
9950 6000
4349 2000
9425 1600
Haymarket
Kogarah
Liverpool
Level 5 Sussex Centre 401 Sussex St
Level 3 St George Private Hospital South St
Ground Floor 16-18 Bigge St
9281 3822
8567 6955
8844 1575
Maroubra
Miranda
Newcastle
Level 1, 225 Maroubra Rd
Suite 4, 20-24 Gibbs St
The Heights Private Medical Centre
2 Lookout Rd New Lambton Heights
8372 3200
8567 6980
4957 8515
St Leonards
Sydney CBD
Wahroonga
16 Marshall Ave
Level 1, 33 York St
Suite 103 Tulloch Building Sydney Adventist
Hospital 185 Fox Valley Road Wahroonga
9439 3158
8346 6800
9425 1780
Westmead
Wollongong
Level 2, 20-22 Mons Rd
Suite 3, 336 Crown St
8844 1550
4271 3900
HUNTER IVF
NEW LAMBTON
HEIGHTS
GOSFORD
WAHROONGA
CASTLE HILL
DEE WHY
CHATSWOOD
WESTMEAD
BURWOOD
GREENWICH
ST LEONARDS
HAYMARKET
.
SYDNEY
BONDI JN
RANDWICK
LIVERPOOL
MAROUBRA
ivf.com.au | 1800 111 IVF
MIRANDA
A member of
HEALTH
WOLLONGONG
COMM-PI-122 | 8MAY2015
KOGARAH
Is Cystic Fibrosis common?
Cystic Fibrosis is the most common life threatening genetic condition
affecting Australian newborns. One in every 2,500 babies, male
or female, born in Australia will have CF. It is estimated one in 25
Caucasian Australians are carriers of CF although they have no
symptoms of the disease. Faulty CF genes are found in people of other
ethnic backgrounds too, however it is not as common, for example the
risk for an Asian person to be a carrier of CF is 1 in 90.
Could your child be at risk of having
Cystic Fibrosis?
·
·
·
Cystic Fibrosis (CF) is the most
common life threatening
condition affecting Australian
newborns
1 in 25 Caucasian Australians
are carriers of a CF gene fault
Screening for CF gene faults
is available at IVFAustralia’s
inhouse genetics laboratory
What is Cystic Fibrosis?
Cystic Fibrosis (CF) is an inherited genetic disorder that affects the
respiratory and digestive system, sweat glands and male fertility from
infancy through to adulthood. The gene involved in CF regulates the
production of a protein in cells that control the movement of salt in and
out of cells. CF causes the formation of thick mucus that traps bacteria,
resulting in infections that damage both the lungs and the gut. Babies
and children with CF need daily physiotherapy for their lungs and
frequent courses of antibiotics to treat the bacterial infections. Despite
modern treatments there is currently no cure and CF sufferers have a
reduced life expectancy.
For a child to have Cystic Fibrosis both parents must be carriers of the
gene fault responsible for CF. When two CF carriers have a child there
is a 1 in 4 chance their child will be affected by CF, a 1 in 2 chance
their child will be a carrier of a CF gene fault though not affected by CF,
and a 1 in 4 chance the child will not inherit any CF gene fault, and
therefore will not be affected by CF or at risk of passing a CF gene fault
to future generations.
Every cell in a person’s body has two copies of Chromosome 7, one
of which they inherit from each parent. If one of those copies has
the gene fault responsible for CF then the person is a ‘carrier’ for the
condition. If a child inherits two copies of Chromosome 7 that both
have a gene fault known to cause CF then the child will have inherited
the CF disorder.
Male CF carriers frequently have a gene fault that is associated
with infertility. You may wish to consider having at least one partner
screened for CF prior to commencing any fertility treatment given the
CF carrier rate is higher in infertile males and many CF carriers are
completely healthy adults with no family history of the disorder.
CF Screening at IVFAustralia
IVFAustralia’s inhouse CF screening program provides a fast result
following a simple blood test of one partner. If the test is negative, the
risk of your child being affected by CF is extremely low and there is no
need for any further concern. If, however, your test identifies you as
a CF carrier, a specialist will recommend that your partner should be
tested. Both parents need to be carriers of the CF mutation in order for
the child to be affected. In the event both partners are carriers a full
explanation of the risk of having a child affected by CF will be provided.
Test Costs
Screening for CF mutations is not covered by Medicare and a fee
of $255 is charged (this expense can go towards out of pocket tax
deduction).
Is Cystic Fibrosis common?
Cystic Fibrosis is the most common life threatening genetic condition
affecting Australian newborns. One in every 2,500 babies, male
or female, born in Australia will have CF. It is estimated one in 25
Caucasian Australians are carriers of CF although they have no
symptoms of the disease. Faulty CF genes are found in people of other
ethnic backgrounds too, however it is not as common, for example the
risk for an Asian person to be a carrier of CF is 1 in 90.
Could your child be at risk of having
Cystic Fibrosis?
·
·
·
Cystic Fibrosis (CF) is the most
common life threatening
condition affecting Australian
newborns
1 in 25 Caucasian Australians
are carriers of a CF gene fault
Screening for CF gene faults
is available at IVFAustralia’s
inhouse genetics laboratory
What is Cystic Fibrosis?
Cystic Fibrosis (CF) is an inherited genetic disorder that affects the
respiratory and digestive system, sweat glands and male fertility from
infancy through to adulthood. The gene involved in CF regulates the
production of a protein in cells that control the movement of salt in and
out of cells. CF causes the formation of thick mucus that traps bacteria,
resulting in infections that damage both the lungs and the gut. Babies
and children with CF need daily physiotherapy for their lungs and
frequent courses of antibiotics to treat the bacterial infections. Despite
modern treatments there is currently no cure and CF sufferers have a
reduced life expectancy.
For a child to have Cystic Fibrosis both parents must be carriers of the
gene fault responsible for CF. When two CF carriers have a child there
is a 1 in 4 chance their child will be affected by CF, a 1 in 2 chance
their child will be a carrier of a CF gene fault though not affected by CF,
and a 1 in 4 chance the child will not inherit any CF gene fault, and
therefore will not be affected by CF or at risk of passing a CF gene fault
to future generations.
Every cell in a person’s body has two copies of Chromosome 7, one
of which they inherit from each parent. If one of those copies has
the gene fault responsible for CF then the person is a ‘carrier’ for the
condition. If a child inherits two copies of Chromosome 7 that both
have a gene fault known to cause CF then the child will have inherited
the CF disorder.
Male CF carriers frequently have a gene fault that is associated
with infertility. You may wish to consider having at least one partner
screened for CF prior to commencing any fertility treatment given the
CF carrier rate is higher in infertile males and many CF carriers are
completely healthy adults with no family history of the disorder.
CF Screening at IVFAustralia
IVFAustralia’s inhouse CF screening program provides a fast result
following a simple blood test of one partner. If the test is negative, the
risk of your child being affected by CF is extremely low and there is no
need for any further concern. If, however, your test identifies you as
a CF carrier, a specialist will recommend that your partner should be
tested. Both parents need to be carriers of the CF mutation in order for
the child to be affected. In the event both partners are carriers a full
explanation of the risk of having a child affected by CF will be provided.
Test Costs
Screening for CF mutations is not covered by Medicare and a fee
of $255 is charged (this expense can go towards out of pocket tax
deduction).
Cystic Fibrosis
IVFAustralia’s Network of Care
Clinic
Consultation & Monitoring
IVFAustralia’s guide to your screening
Consulting Rooms
Bondi Jn
Burwood
Castle Hill
16th Floor Westfield Tower 2, 500 Oxford St
Suite 18 Level 7, 74-76 Burwood
Suite 4, 15-17 Terminus St
8305 9800
8346 6840
9894 4419
Dee Why
Gosford
Greenwich
Level 3, 834 Pittwater Road
Level 2 Suite 24, 207 North Albany St
Level 2, 176 Pacific Highway
9950 6000
4349 2000
9425 1600
Haymarket
Kogarah
Liverpool
Level 5 Sussex Centre 401 Sussex St
Level 3 St George Private Hospital South St
Ground Floor 16-18 Bigge St
9281 3822
8567 6955
8844 1575
Maroubra
Miranda
Newcastle
Level 1, 225 Maroubra Rd
Suite 4, 20-24 Gibbs St
The Heights Private Medical Centre
2 Lookout Rd New Lambton Heights
8372 3200
8567 6980
4957 8515
St Leonards
Sydney CBD
Wahroonga
16 Marshall Ave
Level 1, 33 York St
Suite 103 Tulloch Building Sydney Adventist
Hospital 185 Fox Valley Road Wahroonga
9439 3158
8346 6800
9425 1780
Westmead
Wollongong
Level 2, 20-22 Mons Rd
Suite 3, 336 Crown St
8844 1550
4271 3900
HUNTER IVF
NEW LAMBTON
HEIGHTS
GOSFORD
WAHROONGA
CASTLE HILL
DEE WHY
CHATSWOOD
WESTMEAD
BURWOOD
GREENWICH
ST LEONARDS
HAYMARKET
.
SYDNEY
BONDI JN
RANDWICK
LIVERPOOL
MAROUBRA
ivf.com.au | 1800 111 IVF
MIRANDA
A member of
HEALTH
WOLLONGONG
COMM-PI-122 | 8MAY2015
KOGARAH