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pp 1031-1042 Homeostasis: maintaining stable internal environment How is this done? Last step of the series controls the first A secondary substance increases production of the initial substance Ex. Earth’s Temperature and ice caps Ex. Oxytocin and contractions A secondary substance inhibits production of the initial stimulating substance A = Insulin B = glucagon (sugar) Communication system that controls metabolism, growth, development Uses chemical messengers (hormones) Glands: organs that secrete hormones Hormones: chemical messengers that act on target cells Relies on circulatory system to send chemical message. Size of a pea Produces hormones that affects other glands (thyroid, gonads, adrenal glands) controls growth, metabolism, sexual development, and reproduction Known as “master gland” Growth hormone or GH - GH stimulates growth in childhood and is important for maintaining a healthy body composition. In adults it is also important for maintaining muscle mass and bone mass. It can affect fat distribution in the body. Adrenocorticotropin or ACTH - ACTH stimulates production of cortisol by the adrenal glands. Cortisol, a so-called "stress hormone," is vital to survival. It helps maintain blood pressure and blood glucose levels. Thyroid-stimulating hormone or TSH - TSH stimulates the thyroid gland to make thyroid hormones, which, in turn, control (regulate) the body's metabolism, energy, growth and development, and nervous system activity. Luteinizing hormone or LH - LH regulates testosterone in men and estrogen in women. (gonadotropin) Follicle-stimulating hormone or FSH - FSH promotes sperm production in men and stimulates the ovaries to release eggs (ovulate) in women. LH and FSH work together to allow normal function of the ovaries or testes. (gonadotropin) Oxytocin - Oxytocin causes milk letdown in nursing mothers and contractions during childbirth. Antidiuretic hormone or ADH - ADH, also called vasopressin, is stored in the back part of the pituitary gland and regulates water balance. If this hormone is not secreted properly, this can lead to problems of sodium (salt) and water balance, and could also affect the kidneys so that they do not work as well. Pituitary Disorder • Gigantism: over production of growth hormone • Tallest man recorded: 8 ft 11 in Butterfly-shaped that surrounds trachea Produces thyroxin and calcitonin Regulates heart rate, blood pressure, body temperature, and metabolism Triangle shaped and located on top of kidneys Produces adrenaline Responds to stress Produces insulin and glucagons to regulate blood sugar levels Thymus: stimulates formation of white blood cells (T-cells) Gonads: sex hormones Feature Organs involved Type of Signal (electrical or chemical) Rate of Transfer (fast or slow?) Voluntary or Involuntary? Examples of Processes Controlled Endocrine Nervous System