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PAPER 1 1.Which pair of features is correct for both plant and prokaryotic cells? Plant cell Prokaryotic cell A. Able to change shape Fixed shape B. Contains DNA associated with protein Contains naked DNA C. DNA enclosed by membrane DNA associated with protein D. Chloroplasts may be present Chloroplasts may be present 2.The diagram shows a model of a biological membrane. What do labels I, II, and III illustrate? I II III A. Integral protein Peripheral protein Hydrophobic phosphate head B. Peripheral protein Glycoprotein Hydrophilic phosphate head C. Glycoprotein Integral protein Hydrophilic phosphate head D. Glycoprotein Peripheral protein Hydrophobic phosphate head 3.What describes the functions of the following organelles? Golgi apparatus Rough endoplasmatic reticulum A. Synthesis of proteins for cell secretion ATP production B. ATP production Synthesis of proteins for cell secretion C. Synthesis of proteins for cell secretion Processing of proteins D. Processing of proteins Synthesis of proteins for cell secretion 4.What role does iron play in living organisms? A. As a component in nucleic acids B. As a component of lipids C. As a component of carbohydrates D. As a component of proteins 5.Which diagram correctly illustrates a dipeptide? A. H N C. H O H H C C N C H H H H H C C N H H O H C N H OH H H O N C H B. D. O H H C C N C H H H H O H H C C N C C N OH H H H O C OH H H O C OH 6.What are the components of a DNA nucleotide? A. Deoxyribose, a phosphate and one of the bases: adenine, cytosine, guanine or thymine B. Ribose, a phosphate and one of the bases: adenine, cytosine, guanine or uracil C. Deoxyribose, a nitrate and one of the bases: adenine, cytosine, guanine or thymine D. Ribose, a nitrate and one of the bases: adenine, cytosine, guanine or thymine 7.What is the correct sequence of chemicals produced in the anaerobic respiration pathway? A. Lactate → pyruvate → ethanol B. Ethanol → pyruvate → glucose C. Glucose → lactate → pyruvate D. Glucose → pyruvate → lactate 8.Why do leaves of plants look green? A. Most of the green light is absorbed by chlorophyll and most of the red and blue light is reflected. B. Most of the blue light is absorbed by chlorophyll and most of the red and green light is reflected. C. Most of the red light is absorbed by chlorophyll and most of the green and blue light is reflected. D. Most of the red and blue light is absorbed by chlorophyll and most of the green light is reflected. 9.How would the following DNA sequence, ACGTTGCATGGCA, be transcribed? A. UGCAACGUACCGU B. TGCAACGTACCGT C. ACGTTGCATGGCA D. ACGUUGCAUGGCA 10.what can be concluded on the basis of the following karyotype? A. B. C. D. Female with a normal set of chromosomes Male with Down syndrome Female with Down syndrome Male with a normal set of chromosomes 11.What are homologous chromosomes? A. Two chromosomes with differing sets of genes, in the same sequence, with the same alleles B. Two chromosomes with the same set of genes, in a different sequence, with the same alleles C. Two chromosomes with a different set of genes, in the same sequence, with different alleles D. Two chromosomes with the same set of genes, in the same sequence, sometimes with different alleles 12.Which features of DNA fragments are used to separate them in the process of gel electrophoresis? A. Their charge and their size B. Their charge and base composition C. The sequence of their bases and their charge D. Their base composition and their size 13.Which feature of a genetic pedigree chart demonstrates that a characteristic is sex linked? A. Numbers of offspring carrying the characteristic decreased over several generations. B. One gender is more commonly affected than the other. C. Equal numbers of males and females inherit the characteristic. D. Boys and girls only inherit the characteristic from their mothers. H h 14.What does the genotype X X indicate? A. A co-dominant female B. A heterozygous male C. A heterozygous female D. A co-dominant male 15.If a purple flowered (Pp) and a white flowered pea plant (pp) are crossed, what will the offspring be? A. 1 : 1 ratio of purple and white flowers B. 3 : 1 ratio of purple to white flowers C. 1 : 3 ratio of purple to white flowers D. All purple flowers 16.What is a community? A. A group of producers and consumers living and interacting in an area. B. A group of species living and interacting in an area. C. A group of organisms living and interacting in an area. D. A group of populations living and interacting in an area. 17.What are the main sources of carbon dioxide on earth? A. Cellular respiration of consumers, producers and combustion of fossil fuels B. Photosynthesis and cellular respiration of consumers C. Cellular respiration of producers and combustion of fossil fuels D. Photosynthesis and combustion of fossil fuels 18.The average leaf length of one plant is 2.5 cm with a standard deviation of 0.5 cm. What does this indicate? A. 95% of all leaves fall within the ranges of 2.0 to 3.0 cm B. 68% of all leaves fall within the ranges of 1.5 to 3.5 cm C. 68% of all leaves fall within the ranges of 2.5 to 3.0 cm D. 95% of all leaves fall within the ranges of 1.5 to 3.5 cm 19.What are Allium sativa and Allium cepa? A. Two different species of the same genus B. The same species of the same genus C. The same species but of a different genus D. Two different species of a different genus 20.This diagram represents a simple food chain. In which ways is energy lost between the trophic levels? A. B. C. D. I. II. III. I and II only I and III only II and III only I, II and III Heat loss Material Material not assimilated through not cell respiration consumed 21.In the digestive system, enzyme A has an optimum pH of 1.5 and enzyme B an optimum pH of 7. What are the possible substrates of these enzymes? Enzyme A Enzyme B A. proteins amino acids B. lipids proteins C. carbohydrates lipids D. proteins lipids 22.Which processes are represented by the labels in the diagram below? I II I II A. A phagocyte ingesting a microbe by exocytosis. Digestion of the microbe with the help of the Golgi apparatus. B. A phagocyte ingesting a microbe by endocytosis. Digestion of the microbe with the help of a lysosome. C. A phagocyte ingesting a microbe by exocytosis. Digestion of the microbe with the help of a lysosome. D. A phagocyte ingesting a microbe by endocytosis. Digestion of the microbe with the help of the Golgi apparatus. 23.The diagram below shows the human male reproductive system and associated organs. X Y Z 24. Which of the labelled structures indicate the bladder, prostate and urethra? Bladder Prostate Urethra A. Y X Z B. X Y Z C. Z X Y D. X Z Y 25.What happens during inhalation? A. Both the external intercostal muscles and the diaphragm contract. B. The internal intercostal muscles contract and the diaphragm relaxes. C. The external intercostal muscles relax and the diaphragm contracts. D. Both the internal intercostal muscles and the diaphragm relax. 26.Which of the following best describes the composition of human blood? A. Erythrocytes, leucocytes and platelets B. Erythrocytes, phagocytes and platelets C. Erythrocytes, lymphocytes and platelets D. Erythrocytes, antigens and platelets 27.Which of the following best describes antibodies? A. Made by phagocytes and specific to one antigen B. Made by lymphocytes and specific to one antigen C. Made by leucocytes and non-specific D. Made by phagocytes and non-specific 28.Which play a role in controlling body temperature? I. Blood II. Skin arterioles III. Body hair A. I and II only B. I and III only C. II and III only D. I, II and III 29.In a human diet, what effect does a high intake of both protein and salt have on urea and salt concentrations of urine? Urea Concentration Salt Concentration A. High Low B. Low High C. High High D. Low Low PAPER II PARTE A: Two species of sea snakes, Laticauda laticaudata and Laticauda colubrina, spend most of their lives living in the sea. They must be able to move, hunt and survive in the water, but for short periods they need to come ashore to breed. They inhabit some of the Pacific islands which have low coral cliffs that the snakes need to climb in order to get onto dry land for courtship, mating and laying eggs. Figure 1 Diagram to show a cross-sectional view of cliff used in the study vegetation Height 2.3m sea level Muscle strength / arbitrary units [Source: Terrestrial locomotion in sea snakes: the effects of sex and species on cliff-climbing ability in sea kraits (Serpentes, Elapidae, Laticauda)”, X. Bonnet, I. Ineich and R. Shine, Biological Journal of the Linnean Society, August 2005, vol. 85, issue 4, pages 433-41, Wiley-Blackwell. Used with permission.] The scientists studied the ability of snakes to climb the low cliff. They measured the body mass of the snakes and relative strength of the snakes. The mean results are shown in the bar charts below. 250 Body mass/g 200 150 100 50 0 Females Males 25 20 15 10 5 0 Females Males Key: L. laticaudata L. colubrina [Source: “Terrestrial locomotion in sea snakes: the effects of sex and species on cliff-climbing ability in sea kraits (Serpentes, Elapidae, Laticauda)”, X. Bonnet, I. Ineich and R. Shine, Biological Journal of the Linnean Society, August 2005, vol. 85, issue 4, pages 433-41, Wiley-Blackwell. Used with permission.] (a) State which sex of snake has the greater mean mass. ..................................................................................................................................... (1) (b) State which species of snake is the strongest. ..................................................................................................................................... (c) The error bars represent standard deviation. Deduce which groups of snakes show the greatest variability in body mass. ..................................................................................................................................... (d) For L. colubrina calculate the difference between the strength of the male and the female snakes. ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... (1) (1) (1) The scientists placed male snakes onto the coral cliff near its base. They measured their ability to hold onto the coral cliff. The L. colubrina males climbed much faster than the males of L. laticaudata. The graph below shows the ability of snakes to cling to the coral cliff. 100 Key: L. colubrina 80 L. laticaudata 60 Snakes still clinging to the cliff / % 40 20 0 0 20 40 60 80 100 120 Time / seconds [Source: “Terrestrial locomotion in sea snakes: the effects of sex and species on cliff-climbing ability in sea kraits (Serpentes, Elapidae, Laticauda)”, X. Bonnet, I. Ineich and R. Shine, Biological Journal of the Linnean Society, August 2005, vol. 85, issue 4, pages 433-41, Wiley-Blackwell. Used with permission.] (e) (i) Compare the ability of the two species of snake to cling to the cliff. ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (2) (ii) Suggest two reasons for the difference in the ability of the snakes to cling to the cliffs for 120 seconds. ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (2) (f) Discuss the advantages and disadvantages of body mass in these two species of snake. ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... (3) (Total 11 marks) (a) State the typical size of (i) a bacterium; ...................................................................................................... (1) (ii) an average eukaryotic cell. ............................................................................... (1) (b) (a) Explain the importance of the surface area to volume ratio in limiting cell size. ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... Define homeostasis. ..................................................................................................................................... ..................................................................................................................................... (1) (b) Blood glucose levels are controlled by several hormones. (i) State the name of one of these hormones and the specific site of its production. hormone: ........................................................................................................... site: ................................................................................................................... (2) (ii) Outline how the hormone chosen in (b) (i) controls blood glucose. ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... ........................................................................................................................... (2) (c) Explain the roles of estrogen in regulating change at puberty in young women. ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... (3) (Total 8 marks) (a) Variation occurs at the species level. Explain how sexual reproduction promotes variation in species. ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... (2) (b) Living organisms are classified according to their characteristics using a hierarchy of taxa. State the missing taxa in the table below. Levels in the hierarchy of classification taxa (i) ....................................................................... Phylum (ii) ....................................................................... (iii) ....................................................................... Family (iv) ....................................................................... Species (2) (c) Explain how differentiation results in a variety of different types of cells occurring in a multicellular organism. ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... ..................................................................................................................................... (3) (Total 7 marks) PARTE B PAPER 2 Up to two additional marks are available for the construction of your answers. (2) (a) Draw a labelled diagram showing the fluid-mosaic model of a biological membrane. (b) Explain the processes of active and passive transport that move materials across a membrane. (c) Describe the features of the alveoli that make them well adapted for gaseous exchange. (5) (8) (5) (2) (a) Explain why enzymes are substrate specific and why their activity is affected by substrate concentration. (b) Outline the use of restriction enzymes (endonucleases) and DNA ligase in gene technology. (c) Outline the role of two enzymes found in the digestive system of humans. (8) (6) (4 (2) (a) List the characteristics of alveoli that permit efficient gas exchange. (b) Describe the structures of arteries and veins as related to their functions. (c) Explain the process of aerobic cell respiration. (4) (6) (8)