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The cells and tissues that recognize and attack foreign substances in the body Causes of Disease Noninfectious Disease: Cannot be spread from one individual to another Infectious Disease: Caused by a pathogen and can be spread from one individual to another Pathogen: A microorganism, a virus, or a protein that causes a disease Pathways to Pathogens Air Contaminated Objects Person to person Animals Food and Water Putting Pathogens in their place Pasteurization Vaccines & Immunity Antibiotics Immunity: The ability to resist or to recover from an infectious disease Cells of the Immune System Macrophages: Engulfs pathogens and other materials T cell: Coordinates the immune system and attacks many infected cells B cell: A white blood cell that makes antibodies Antibody: A protein made by B cells that binds to a specific antigen. Antigen: Substances that stimulate an immune response Memory B Cells A B cell that responds to an antigen more strongly when the body is reinfected with an antigen than it does during its first encounter with the antigen. Fevers Fevers of a couple degrees help immune cells reproduce and help your body fight infections Fevers more than a couple degrees can be dangerous however. Challenges to the Immune System Allergies (When the immune system overreacts to antigens that are not dangerous to the body. Autoimmune diseases (A disease in which the immune system attacks the organism’s own cells; ex: rheumatoid arthritis, diabetes, multiple sclerosis) Cancer (A disease in which the cells begin dividing at an uncontrolled rate and become invasive) AIDS (acquired immune deficiency syndrome); When HIV (human immunodeficiency virus) kills helper T cells. People with AIDS rarely die from AIDS itself, rather from other diseases they cant fight off)