No Slide Title
... • Anomalies may be detected molecularly providing new tools for cancer screening or detection of relapse • Since the cell-cycle is essential for cell-proliferation, inhibitors of the cell-cycle are anti-proliferative agents useful in a variety of clinical settings (cancer, inflammation, re-stenosis ...
... • Anomalies may be detected molecularly providing new tools for cancer screening or detection of relapse • Since the cell-cycle is essential for cell-proliferation, inhibitors of the cell-cycle are anti-proliferative agents useful in a variety of clinical settings (cancer, inflammation, re-stenosis ...
University of Bucharest, Faculty of Biology, Molecular Biology Center
... in Holstein cattle characterized by a greatly reduced level of expression of the β2 heterodimeric integrin. Integrins are adhesion molecules that mediate the entry and passage of neutrophiles across membranes to destroy invading pathogens [6; 9; 10]. The molecular basis of BLAD is a single point mut ...
... in Holstein cattle characterized by a greatly reduced level of expression of the β2 heterodimeric integrin. Integrins are adhesion molecules that mediate the entry and passage of neutrophiles across membranes to destroy invading pathogens [6; 9; 10]. The molecular basis of BLAD is a single point mut ...
manuscript pdf
... with a T-DNA. DMA gel blot analyses indicated that the transformants contained an intact DEF gene (data not shown) with a copy number of one (TDF3), two (TDF2), or approximately six(TDF1). Two of the three lines containing DEF, TDF1 and TDF2, had a floral phenotype distinct from the wild type that s ...
... with a T-DNA. DMA gel blot analyses indicated that the transformants contained an intact DEF gene (data not shown) with a copy number of one (TDF3), two (TDF2), or approximately six(TDF1). Two of the three lines containing DEF, TDF1 and TDF2, had a floral phenotype distinct from the wild type that s ...
Application of rpoB sequence similarity analysis, REP‐PCR and
... In terms of the 16S rRNA gene sequences of Geobacillus and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement with Zeigler (2005) who confirmed 16S rRNA gene sequences similarity of Geobacillus type strains, higher than 98Æ5%. Despite the general us ...
... In terms of the 16S rRNA gene sequences of Geobacillus and Bacillus type strains and isolates, similarity values among 90% and 100% were retrieved, in agreement with Zeigler (2005) who confirmed 16S rRNA gene sequences similarity of Geobacillus type strains, higher than 98Æ5%. Despite the general us ...
7nQ Jj I f NO "7^07 - UNT Digital Library
... My ultimate goal is to offer students the knowledge that I have received and allow them to use it in their own way. I am sure that I will come across many students who want to become physicians, and I believe that a genetics course will certainly help prepare them for the medical field. Other studen ...
... My ultimate goal is to offer students the knowledge that I have received and allow them to use it in their own way. I am sure that I will come across many students who want to become physicians, and I believe that a genetics course will certainly help prepare them for the medical field. Other studen ...
Epigenetic Regulation ofbdnfGene Transcription in the
... learning induced differential regulation of exon-specific bdnf mRNAs (I, IV, VI, IX) that was associated with changes in bdnf DNA methylation and altered local chromatin structure. Infusions of zebularine (a DNA methyltransferase inhibitor) significantly altered bdnf DNA methylation and triggered ch ...
... learning induced differential regulation of exon-specific bdnf mRNAs (I, IV, VI, IX) that was associated with changes in bdnf DNA methylation and altered local chromatin structure. Infusions of zebularine (a DNA methyltransferase inhibitor) significantly altered bdnf DNA methylation and triggered ch ...
2012_4 The-new-Federal-anti-counterfeiting-mandate-for-military-electronics
... Paradoxically, even as the U.S. military has come to depend on advanced electronics, it is today a minor buyer of electronic parts compared to commercial manufacturers. Only about 2% of the global production of microchips is procured by the Department of Defense.6 So the power of the DOD to dictate ...
... Paradoxically, even as the U.S. military has come to depend on advanced electronics, it is today a minor buyer of electronic parts compared to commercial manufacturers. Only about 2% of the global production of microchips is procured by the Department of Defense.6 So the power of the DOD to dictate ...
References - Plant Developmental Biology
... Confocal laser scanning microscopy (CLSM) represents one of the most significant advances in optical microscopy ever developed. This technique enables visualization deep within both living and fixed cells and tissues and affords the ability to collect sharply defined images of cellular components or ...
... Confocal laser scanning microscopy (CLSM) represents one of the most significant advances in optical microscopy ever developed. This technique enables visualization deep within both living and fixed cells and tissues and affords the ability to collect sharply defined images of cellular components or ...
cis-Regulatory Elements and trans-Acting Factors
... primary and secondary cultures produce large quantities of renin, predominantly in the prorenin form, and are easily accessible.14 Renin regulation in this model was studied and showed a role of cAMP and protein kinase C.15 This is similar to the regulation demonstrated in primary cultures of JG cel ...
... primary and secondary cultures produce large quantities of renin, predominantly in the prorenin form, and are easily accessible.14 Renin regulation in this model was studied and showed a role of cAMP and protein kinase C.15 This is similar to the regulation demonstrated in primary cultures of JG cel ...
Functions of DNA methylation: islands, start sites, gene bodies and
... there is abundant evidence that methylated CGIs at TSSs are associated with some silent genes, the timing of de novo methylation with respect to gene silencing is now beginning to be elucidated. The function of DNA methylation is intrinsically linked to the mechanisms for establishing, maintaining a ...
... there is abundant evidence that methylated CGIs at TSSs are associated with some silent genes, the timing of de novo methylation with respect to gene silencing is now beginning to be elucidated. The function of DNA methylation is intrinsically linked to the mechanisms for establishing, maintaining a ...
T cell antigen receptor diversity Generation of
... factors from the AP-1 family such as Fos and Jun. • Increases in intracellular calcium via IP3 IP3, produced by PLC-, binds to calcium channels in the ER and releases intracellular stores of Ca++ into the cytosol. Increased intracellular [Ca++] activate a phospatase, calcineurin, which in turn acti ...
... factors from the AP-1 family such as Fos and Jun. • Increases in intracellular calcium via IP3 IP3, produced by PLC-, binds to calcium channels in the ER and releases intracellular stores of Ca++ into the cytosol. Increased intracellular [Ca++] activate a phospatase, calcineurin, which in turn acti ...
No Slide Title
... factors from the AP-1 family such as Fos and Jun. • Increases in intracellular calcium via IP3 IP3, produced by PLC-, binds to calcium channels in the ER and releases intracellular stores of Ca++ into the cytosol. Increased intracellular [Ca++] activate a phospatase, calcineurin, which in turn acti ...
... factors from the AP-1 family such as Fos and Jun. • Increases in intracellular calcium via IP3 IP3, produced by PLC-, binds to calcium channels in the ER and releases intracellular stores of Ca++ into the cytosol. Increased intracellular [Ca++] activate a phospatase, calcineurin, which in turn acti ...
Point mutations in BCL6 DNA-binding domain reveal distinct
... respectively) on B6(9)-SV40-Luc. Thus, these two proteins have the ability to bind to the reporter and to inhibit transcription to the same extent as the wild type protein. By contrast, BCL6 proteins carrying a mutation in any one of the remaining ZFs (mutants 3–6) exhibited a dramatic loss in their ...
... respectively) on B6(9)-SV40-Luc. Thus, these two proteins have the ability to bind to the reporter and to inhibit transcription to the same extent as the wild type protein. By contrast, BCL6 proteins carrying a mutation in any one of the remaining ZFs (mutants 3–6) exhibited a dramatic loss in their ...
Genetic characterization of the mitochondrial DNA - (BORA)
... on opposite DNA strands, as well as genes on the same strand (Wolstenholme, 1992b). Within the metazoans the mitochondrial genomes range in size from 14 – 42 kb (Crease, 1999). This variation in size can to some extent be due to differences in gene length, but in most cases it is a result of size di ...
... on opposite DNA strands, as well as genes on the same strand (Wolstenholme, 1992b). Within the metazoans the mitochondrial genomes range in size from 14 – 42 kb (Crease, 1999). This variation in size can to some extent be due to differences in gene length, but in most cases it is a result of size di ...
How dormant origins promote complete genome replication
... entry into S phase if the number is insufficient [5,6]. In addition to being regulated during different phases of the cell cycle, the licensing system is inactivated when cells exit the cell cycle either reversibly into G0 or irreversibly as a consequence of terminal differentiation or senescence. N ...
... entry into S phase if the number is insufficient [5,6]. In addition to being regulated during different phases of the cell cycle, the licensing system is inactivated when cells exit the cell cycle either reversibly into G0 or irreversibly as a consequence of terminal differentiation or senescence. N ...
blumberg-lab.bio.uci.edu
... nucleosome remodeling ● Contains key protein in chromosome structure ● Genes are linked to behavior and tissue specific processes ...
... nucleosome remodeling ● Contains key protein in chromosome structure ● Genes are linked to behavior and tissue specific processes ...
08_chapter 1
... absolute ATS and GCS values differ from each other. All 36 prokaryote chromosomes showed that ATS and GCS in the entire regio~ are almost zero. 1.2.1.1. Studies using regression analysis on sample DNA fragments A generalized presentation on the Chargaffs 2nd parity was given by Prabhu (1993). He stu ...
... absolute ATS and GCS values differ from each other. All 36 prokaryote chromosomes showed that ATS and GCS in the entire regio~ are almost zero. 1.2.1.1. Studies using regression analysis on sample DNA fragments A generalized presentation on the Chargaffs 2nd parity was given by Prabhu (1993). He stu ...
Microcin B17 Blocks DNA Replication and Induces
... the colicins, is non-lethal for the producing cell, and is not stimulated by agents which induce the SOS response (Baquero & Moreno, 1984). In most cases microcin production is plasmiddependent and, hitherto, five types of microcins have been identified by cross-immunity, biochemical and genetic cri ...
... the colicins, is non-lethal for the producing cell, and is not stimulated by agents which induce the SOS response (Baquero & Moreno, 1984). In most cases microcin production is plasmiddependent and, hitherto, five types of microcins have been identified by cross-immunity, biochemical and genetic cri ...
Identifikasi Molekular Bakteri Pathogen yang Menginfeksi Hama
... rDNA. The terms have veen used interchangeably (Clarridge, 2004). Using 16s rDNA primers, a predicted band for red bacteria DNA template was obtained (Figure 2). As the DNA double helix unwinds, RNA molecules read the template that is provided from this DNA sequence and an rRNA molecule is formed. S ...
... rDNA. The terms have veen used interchangeably (Clarridge, 2004). Using 16s rDNA primers, a predicted band for red bacteria DNA template was obtained (Figure 2). As the DNA double helix unwinds, RNA molecules read the template that is provided from this DNA sequence and an rRNA molecule is formed. S ...
Boundary elements and nuclear organization
... for a variety of identified insulator elements (for a list of such elements, see West et al., 2002), suggestive of their role in preserving the separation between heterochromatin and euchromatin. Recently, the heterochromatic repressive chromatin has been characterized by several molecular marks, pr ...
... for a variety of identified insulator elements (for a list of such elements, see West et al., 2002), suggestive of their role in preserving the separation between heterochromatin and euchromatin. Recently, the heterochromatic repressive chromatin has been characterized by several molecular marks, pr ...
Introduction and Preliminaries - Department of Computer and
... a human genome Model of sequence alignment is not appropriate for human genome comparison since the differences are not in terms of insertions/deletion/mutations of a nucleotide, but a rearrangement of a long DNA regions The basic comparison is gene My T. Thai [email protected] ...
... a human genome Model of sequence alignment is not appropriate for human genome comparison since the differences are not in terms of insertions/deletion/mutations of a nucleotide, but a rearrangement of a long DNA regions The basic comparison is gene My T. Thai [email protected] ...
Expressed Sequence Tag (EST)
... - They represent a big part of the mammalian genome - They are found in a number of genomes (plants, …) - They induce errors in clustering and assembling - They should be MASKED, not deleted, to avoid false sequence assembling (also interesting for evolutionary studies. SSRs important for mapping of ...
... - They represent a big part of the mammalian genome - They are found in a number of genomes (plants, …) - They induce errors in clustering and assembling - They should be MASKED, not deleted, to avoid false sequence assembling (also interesting for evolutionary studies. SSRs important for mapping of ...
PDF
... Maternal effects have been genetically defined by mutations that affect the next generation when inherited from the mother. Maternal effect genes play an essential role in early development in many animal species (Riechmann and Ephrussi, 2001; Sardet et al., 2004). In plants, the maternal contributi ...
... Maternal effects have been genetically defined by mutations that affect the next generation when inherited from the mother. Maternal effect genes play an essential role in early development in many animal species (Riechmann and Ephrussi, 2001; Sardet et al., 2004). In plants, the maternal contributi ...
North Kitsap High School PAL Program
... population size, differentiate between density-dependent and density-independent factors, describe how the size of the human population has changed over time. (6) Describe human activities that can affect the biosphere, identify the characteristics of sustainable development, define biodiversity and ...
... population size, differentiate between density-dependent and density-independent factors, describe how the size of the human population has changed over time. (6) Describe human activities that can affect the biosphere, identify the characteristics of sustainable development, define biodiversity and ...
Rapid and Quantitative Detection of Toxoplasma Gondii by PCR
... can be achieved by tissue culture or mouse inoculation. However, tissue culture is not very sensitive and inoculation of mice takes more than three weeks to complete [2]. PCR overcomes these shortcomings [3]. PCR is sensitive and the diagnosis can be confirmed within one day. The use of PCR has grea ...
... can be achieved by tissue culture or mouse inoculation. However, tissue culture is not very sensitive and inoculation of mice takes more than three weeks to complete [2]. PCR overcomes these shortcomings [3]. PCR is sensitive and the diagnosis can be confirmed within one day. The use of PCR has grea ...
Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.