Regulation of Na/K-ATPase β1 -subunit gene
... Partial inhibition of Na/K-ATPase by ouabain causes hypertrophic growth and regulates several early and late response genes, including that of Na/K-ATPase α3 subunit, in cultured neonatal rat cardiac myocytes. The aim of this work was to determine whether ouabain and other hypertrophic stimuli affec ...
... Partial inhibition of Na/K-ATPase by ouabain causes hypertrophic growth and regulates several early and late response genes, including that of Na/K-ATPase α3 subunit, in cultured neonatal rat cardiac myocytes. The aim of this work was to determine whether ouabain and other hypertrophic stimuli affec ...
CpG Mutation Rates in the Human Genome Are
... any measurable effect on the amount of energy required to melt DNA (Almagor and Cole 1989). Thus, it is clear that DNA does melt reversibly (‘‘breathe’’) under physiological conditions, and this melting must have an effect on the rates of cytosine deamination. The question then becomes the quantitat ...
... any measurable effect on the amount of energy required to melt DNA (Almagor and Cole 1989). Thus, it is clear that DNA does melt reversibly (‘‘breathe’’) under physiological conditions, and this melting must have an effect on the rates of cytosine deamination. The question then becomes the quantitat ...
Diversity of DNA methyltransferases that recognize asymmetric
... Multiple lines of evidence suggest that some DNA MTases function as dimers. Further, functional analysis of many restriction-modification systems showed the presence of more than one or fused MTase genes. It was proposed that presence of two MTases responsible for the recognition and methylation of ...
... Multiple lines of evidence suggest that some DNA MTases function as dimers. Further, functional analysis of many restriction-modification systems showed the presence of more than one or fused MTase genes. It was proposed that presence of two MTases responsible for the recognition and methylation of ...
The rapidly evolving field of plant centromeres
... satellite evolution is driven by the selection and coevolution of satellites and centromere-binding proteins, rather than by random genetic drift. This requires that certain centromere satellite variants confer a selective advantage upon meiotic cells (i.e. eggs and sperm), a process known as meioti ...
... satellite evolution is driven by the selection and coevolution of satellites and centromere-binding proteins, rather than by random genetic drift. This requires that certain centromere satellite variants confer a selective advantage upon meiotic cells (i.e. eggs and sperm), a process known as meioti ...
Nucleic acid hybridisation and polymerase chain reaction
... - absence of polypurines or polypirimidines - absence of secondary structure - absence of complementarity, particularly at the 3 ' end, which may p r o m o t e the formation of an artifact called "primer dimer". Computer programmes, available upon request, can help to perform this task (62). Since t ...
... - absence of polypurines or polypirimidines - absence of secondary structure - absence of complementarity, particularly at the 3 ' end, which may p r o m o t e the formation of an artifact called "primer dimer". Computer programmes, available upon request, can help to perform this task (62). Since t ...
Multifractal characterisation of length sequences of coding and
... PII: S 0 3 7 8 - 4 3 7 1 ( 0 1 ) 0 0 3 9 1 - 0 ...
... PII: S 0 3 7 8 - 4 3 7 1 ( 0 1 ) 0 0 3 9 1 - 0 ...
Mutations in SIN4 and RGR1 Cause Constitutive Expression of MAL
... al. 2002). It is possible that the MAL-activator itself is the maltose-binding sensor. Alternatively, other positive or negative regulators may be involved but may not have been identified as yet because they are encoded by repeated or essential genes. To identify possible additional players involve ...
... al. 2002). It is possible that the MAL-activator itself is the maltose-binding sensor. Alternatively, other positive or negative regulators may be involved but may not have been identified as yet because they are encoded by repeated or essential genes. To identify possible additional players involve ...
Chapter 1: Organization of the Human Body
... Phagocytosis—intake of large particles, as when white blood cells take in waste materials; also pinocytosis (intake of fluid), and receptor-mediated endocytosis, requiring binding sites in the plasma ...
... Phagocytosis—intake of large particles, as when white blood cells take in waste materials; also pinocytosis (intake of fluid), and receptor-mediated endocytosis, requiring binding sites in the plasma ...
Degree Thesis Adoption of EBPP by DNA: Are Customers
... Finland. But business is business whether it is B2B or B2C, they need to take compensation for the services they have been providing to their clients. All the business organizations deals these kind of process first by sending invoice to the customers and accordingly customers will pay the bills as ...
... Finland. But business is business whether it is B2B or B2C, they need to take compensation for the services they have been providing to their clients. All the business organizations deals these kind of process first by sending invoice to the customers and accordingly customers will pay the bills as ...
Deconstructing host-pathogen interactions in Drosophila
... recessive mutations (or mutants with opposing phenotypes) in a given pathway to determine the sequence in which genes act in that pathway. These versatile tools, combined with the rapid Drosophila life cycle, allow detailed genetic analysis of virulence factors that act on tissues or organs; such ex ...
... recessive mutations (or mutants with opposing phenotypes) in a given pathway to determine the sequence in which genes act in that pathway. These versatile tools, combined with the rapid Drosophila life cycle, allow detailed genetic analysis of virulence factors that act on tissues or organs; such ex ...
Aucun titre de diapositive - Universidad Nacional De Colombia
... Build clusters of genes and mRNAs (GenBank). Add ESTs to previous clusters (megablast). ESTs that join two clusters of genes/mRNAs are discarded. Any resulting cluster without a polyadenylation signal or at least two 3’ ESTs is discarded. The resulting clusters are called anchored clusters since the ...
... Build clusters of genes and mRNAs (GenBank). Add ESTs to previous clusters (megablast). ESTs that join two clusters of genes/mRNAs are discarded. Any resulting cluster without a polyadenylation signal or at least two 3’ ESTs is discarded. The resulting clusters are called anchored clusters since the ...
Fulltext PDF - Indian Academy of Sciences
... Heritable information in plants consists of genomic information in DNA sequence and epigenetic information superimposed on DNA sequence. The latter is in the form of cytosine methylation at CG, CHG and CHH elements (where H = A, T or C) and a variety of histone modifications in nucleosomes. The epial ...
... Heritable information in plants consists of genomic information in DNA sequence and epigenetic information superimposed on DNA sequence. The latter is in the form of cytosine methylation at CG, CHG and CHH elements (where H = A, T or C) and a variety of histone modifications in nucleosomes. The epial ...
Virp1 Is a Host Protein with a Major Role in Potato - IMBB
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
... Viroids are small, circular, single-stranded RNA molecules that, while not coding for any protein, cause several plant diseases. Viroids rely for their infectious cycle on host proteins, most of which are likely to be involved in endogenous RNA-mediated phenomena. Therefore, characterization of host ...
Gene Section ID4 (inhibitor of DNA binding 4, dominant negative helix-loop-helix protein)
... Hypermethylation of ID4 promoter and ID4 mRNA suppression was found in breast cancer cell lines as well as in primary breast cancers. In one study, it was a significant risk factor for nodal metastasis (Umetani et al., 2006). In another study, BRCA1, ER (estrogen receptor), and ID4 were found expres ...
... Hypermethylation of ID4 promoter and ID4 mRNA suppression was found in breast cancer cell lines as well as in primary breast cancers. In one study, it was a significant risk factor for nodal metastasis (Umetani et al., 2006). In another study, BRCA1, ER (estrogen receptor), and ID4 were found expres ...
Class17 1-31 Win16 Cell Cycle Notes
... following promoters is more likely to give high expression levels: ATTGGTGATC or AGTGCTTATT? (only one strand is shown) What are the molecular interactions that determine the level of expression in either [high glucose, high lactose] or [low glucose, low lactose]? – Why do these make logical sense ...
... following promoters is more likely to give high expression levels: ATTGGTGATC or AGTGCTTATT? (only one strand is shown) What are the molecular interactions that determine the level of expression in either [high glucose, high lactose] or [low glucose, low lactose]? – Why do these make logical sense ...
Package `BitSeq`
... Maximum number of threads to be used. The program will not use more threads that there are MCMC chains. Advanced options: ...
... Maximum number of threads to be used. The program will not use more threads that there are MCMC chains. Advanced options: ...
Figure S1. Interactions between AS1 and CO proteins that contains
... Twenty four-day-old plants grown on soil in short days were harvested at ZT 4. ACT2 was used as an internal control. The means and S.D. were based on three independent experiments. ...
... Twenty four-day-old plants grown on soil in short days were harvested at ZT 4. ACT2 was used as an internal control. The means and S.D. were based on three independent experiments. ...
Methods for detection of point mutations
... fragment, assay performance is dependent on the concentration of glycerol within the gel and the constancy of temperature during gel electrophoresis. Except for G to T transversions, there appears to be no significant effect of the type of base exchange on sensitivity [21]. In comparison with DNA-SS ...
... fragment, assay performance is dependent on the concentration of glycerol within the gel and the constancy of temperature during gel electrophoresis. Except for G to T transversions, there appears to be no significant effect of the type of base exchange on sensitivity [21]. In comparison with DNA-SS ...
A Tn 10-lacZ-kanR-URA3 Gene Fusion Transposon for Insertion Mutagenesis and Fusion Analysis of Yeast and Bacterial Genes.
... cloned yeast genes; it can equally well be used for analysis of prokaryotic genes. We have applied this element to analysis of the LEU2, RADSO, and CDC48 genes of Saccharomyces cerevisiae. This transposon, nicknamed mini-Tn 10-LUK, contains a lacZ gene without efficient transcription or translation ...
... cloned yeast genes; it can equally well be used for analysis of prokaryotic genes. We have applied this element to analysis of the LEU2, RADSO, and CDC48 genes of Saccharomyces cerevisiae. This transposon, nicknamed mini-Tn 10-LUK, contains a lacZ gene without efficient transcription or translation ...
PDF
... Orientation of the field is another possible variable. Horizontal magnets induce horizontal magnetic dipole in the bead (Figure 2A). Such beads follow the magnets as the magnets are rotated. This configuration is required if one is interested in twisting macromolecules. Vertical orientation of the f ...
... Orientation of the field is another possible variable. Horizontal magnets induce horizontal magnetic dipole in the bead (Figure 2A). Such beads follow the magnets as the magnets are rotated. This configuration is required if one is interested in twisting macromolecules. Vertical orientation of the f ...
A disproportionate role for mtDNA in DobzhanskyMuller
... Dobzhansky–Muller (DM) model nicely accounts for the evolution of such incompatibilities. Although DM incompatibilities were originally conceived as resulting of interactions between nuclear genes, recent studies have documented cases where incompatibilities have arisen between nuclear and mitochond ...
... Dobzhansky–Muller (DM) model nicely accounts for the evolution of such incompatibilities. Although DM incompatibilities were originally conceived as resulting of interactions between nuclear genes, recent studies have documented cases where incompatibilities have arisen between nuclear and mitochond ...
No Slide Title
... • Anomalies may be detected molecularly providing new tools for cancer screening or detection of relapse • Since the cell-cycle is essential for cell-proliferation, inhibitors of the cell-cycle are anti-proliferative agents useful in a variety of clinical settings (cancer, inflammation, re-stenosis ...
... • Anomalies may be detected molecularly providing new tools for cancer screening or detection of relapse • Since the cell-cycle is essential for cell-proliferation, inhibitors of the cell-cycle are anti-proliferative agents useful in a variety of clinical settings (cancer, inflammation, re-stenosis ...
Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.