My PP Genetics
... Copyright © 2007 Pearson Education, Inc., publishing as Pearson Addison-Wesley ...
... Copyright © 2007 Pearson Education, Inc., publishing as Pearson Addison-Wesley ...
Constitutive expression of catABC genes in the aniline
... The aniline-assimilating bacterium Rhodococcus sp. AN-22 was found to constitutively synthesize CatB (cis,cis-muconate cycloisomerase) and CatC (muconolactone isomerase) in its cells growing on non-aromatic substrates, in addition to the previously reported CatA (catechol 1,2-dioxygenase). The bacte ...
... The aniline-assimilating bacterium Rhodococcus sp. AN-22 was found to constitutively synthesize CatB (cis,cis-muconate cycloisomerase) and CatC (muconolactone isomerase) in its cells growing on non-aromatic substrates, in addition to the previously reported CatA (catechol 1,2-dioxygenase). The bacte ...
Towards identifying the full set of genes involved in post
... ascorbate and a guiacol peroxidase which ...
... ascorbate and a guiacol peroxidase which ...
20. Transposable Genetic Elements
... location to another. These findings were viewed with skepticism for many years, but it is now clear that such mobile elements are widespread in nature. A variety of colorful names (some of which help to describe their respective properties) have been applied to these genetic elements: controlling el ...
... location to another. These findings were viewed with skepticism for many years, but it is now clear that such mobile elements are widespread in nature. A variety of colorful names (some of which help to describe their respective properties) have been applied to these genetic elements: controlling el ...
Solid Tumour Section Mesothelioma: t(14;22)(q32;q12) in mesothelioma Atlas of Genetics and Cytogenetics
... number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DNA binding domain of YY1 and thus may act as ...
... number NM_013986 version 3; former exon 7 in sequence with accession number X66899) is fused to exon 2 of YY1 (nucleotide 1160 accession number NM_003403 version 3). The putative EWSR1-YY1 protein would contain the transactivation domain of EWSR1 and the DNA binding domain of YY1 and thus may act as ...
Price, DK, Zhang, F, Ashley, CT and Warren, ST: The chicken FMR1 gene is highly conserved containing a CTT 5\' untranslated repeat and encodes an RNA-binding protein. Genomics 31:3-12 (1996).
... Compared to human FMR1, the chicken nucleotide sequence was 85% identical within the coding region. Notably, identity within the 3* UTR was 81%, with highest levels of identity (ú94%) localized to two distinct blocks of 3* sequence located approximately 60 and 600 bp downstream of the translational ...
... Compared to human FMR1, the chicken nucleotide sequence was 85% identical within the coding region. Notably, identity within the 3* UTR was 81%, with highest levels of identity (ú94%) localized to two distinct blocks of 3* sequence located approximately 60 and 600 bp downstream of the translational ...
Interactions of Mitochondrial and Nuclear Genes
... the expected wild-type protein. A number of articles have appeared in which an abnormal gene or mtDNA arrangement has been detected in a collection of CMS lines but not in a collection of fertile lines. Without some corroboration, these differences cannot be concluded to be causal with respect to CM ...
... the expected wild-type protein. A number of articles have appeared in which an abnormal gene or mtDNA arrangement has been detected in a collection of CMS lines but not in a collection of fertile lines. Without some corroboration, these differences cannot be concluded to be causal with respect to CM ...
... novel junctions created by ligation of sequences that were in close proximity through specific interactions. To determine if the Kcnq1 promoter associated with specific DNA sequences in the neonatal heart, we performed an unbiased, systematic 3C scan extending 12.6 kb upstream of the promoter, spann ...
Evolutionary dynamics of RNA-like replicator systems
... Interestingly, a similar situation exists in RNA and DNA. RNA and DNA are chemically very similar to each other, the only difference being the presence or absence of one oxygen atom per nucleotide. Although RNA molecules are the only templates from which proteins are translated in the cell, DNA can ...
... Interestingly, a similar situation exists in RNA and DNA. RNA and DNA are chemically very similar to each other, the only difference being the presence or absence of one oxygen atom per nucleotide. Although RNA molecules are the only templates from which proteins are translated in the cell, DNA can ...
Structural maintenance of chromosome complexes and bone
... ATRX.15–16 Yet, the mechanism through which cohesin localizes to regulatory elements and affects gene expression is poorly understood. During development, sets of genes are activated or suppressed according to a precise program. Changes in the higher order of chromatin can affect gene expression lev ...
... ATRX.15–16 Yet, the mechanism through which cohesin localizes to regulatory elements and affects gene expression is poorly understood. During development, sets of genes are activated or suppressed according to a precise program. Changes in the higher order of chromatin can affect gene expression lev ...
CHAPTER 7 TUNING THE DRAGON PROMOTER FINDER SYSTEM FOR HUMAN PROMOTER RECOGNITION
... been published elsewhere, the tuning process of this complex system has not described previously. We thus present here the details of the tuning process for Dragon Promoter Finder system. The tuning process is performed using Gembicki’s goal attainment optimization process. Our sy ...
... been published elsewhere, the tuning process of this complex system has not described previously. We thus present here the details of the tuning process for Dragon Promoter Finder system. The tuning process is performed using Gembicki’s goal attainment optimization process. Our sy ...
Genetics - Muscular Dystrophy Canada
... First, the DNA sequence must be copied into a message. This message is the blueprint for protein. The building blocks of this blueprint, called messenger RNA or mRNA, are molecules called ribonucleic acid. The blueprint for protein is included in exons, and exons are separated by DNA sequences calle ...
... First, the DNA sequence must be copied into a message. This message is the blueprint for protein. The building blocks of this blueprint, called messenger RNA or mRNA, are molecules called ribonucleic acid. The blueprint for protein is included in exons, and exons are separated by DNA sequences calle ...
Probing b-Lactamase Structure and Function Using Random Replacement Mutagenesis.
... residue positions are actually important for the structure and function of the protein as well as where those important regions lie. Detailed information about the sequence requirements of individual residues is obtained by sequencing functional substitutions. The amino acid side chain characteristi ...
... residue positions are actually important for the structure and function of the protein as well as where those important regions lie. Detailed information about the sequence requirements of individual residues is obtained by sequencing functional substitutions. The amino acid side chain characteristi ...
The Genetics of SMA - Families of SMA Canada
... First, the DNA sequence must be copied into a message. This message is the blueprint for protein. The building blocks of this blueprint, called messenger RNA or mRNA, are molecules called ribonucleic acid. The blueprint for protein is included in exons, and exons are separated by DNA sequences calle ...
... First, the DNA sequence must be copied into a message. This message is the blueprint for protein. The building blocks of this blueprint, called messenger RNA or mRNA, are molecules called ribonucleic acid. The blueprint for protein is included in exons, and exons are separated by DNA sequences calle ...
Sequence of the Tribolium castaneum Homeotic Complex
... purified and sequenced by automated protocols at the Sequencing and Genotyping Facility in the Department of Plant Pathology at Kansas State University. Files containing Escherichia coli DNA sequence were removed from the data set and BAC contigs were constructed using PHRED, PHRAP, and CONSED (Ewin ...
... purified and sequenced by automated protocols at the Sequencing and Genotyping Facility in the Department of Plant Pathology at Kansas State University. Files containing Escherichia coli DNA sequence were removed from the data set and BAC contigs were constructed using PHRED, PHRAP, and CONSED (Ewin ...
Agarose Gel Electrophoresis
... An important feature to consider when selecting a mini- or midigel apparatus is the volume of buffer held by the gel tank. As smaller gels are typically run at high voltages (>10 V/cm), electrophoresis buffers are quickly exhausted, and it is therefore advantageous to choose a gel apparatus with a r ...
... An important feature to consider when selecting a mini- or midigel apparatus is the volume of buffer held by the gel tank. As smaller gels are typically run at high voltages (>10 V/cm), electrophoresis buffers are quickly exhausted, and it is therefore advantageous to choose a gel apparatus with a r ...
Parental Methamphetamine Exposure Affects Offspring`s Behavior and
... Environmetal intervention: Exposure to metamphetamine • Methamphetamine is a major drug of abuse in many parts of the world. Current use of METH surpasses the use of cocaine and opiates. • Methamphetamine addiction is associated with psychotic behavior and long term cognitive impairment. • Surveys ...
... Environmetal intervention: Exposure to metamphetamine • Methamphetamine is a major drug of abuse in many parts of the world. Current use of METH surpasses the use of cocaine and opiates. • Methamphetamine addiction is associated with psychotic behavior and long term cognitive impairment. • Surveys ...
The legal, social and ethical controversy of the collection and
... cells, tissues, organs, and body [4, p.8]. In short it can be likened to “God’s signature” [6, p.259]. Every single human has a unique composition, save for identical twins who share the same genotype but have subtly different phenotypes. When DNA samples are taken from blood cells, saliva or hair b ...
... cells, tissues, organs, and body [4, p.8]. In short it can be likened to “God’s signature” [6, p.259]. Every single human has a unique composition, save for identical twins who share the same genotype but have subtly different phenotypes. When DNA samples are taken from blood cells, saliva or hair b ...
brat regulates cell growth and rRNA synthesis
... importance. For example, the oncogenes Myc, Ras and Cyclin D (Prober and Edgar, 2001) and the tumor suppressors retinoblastoma (White, 1997) and Pten (Gao et al., 2000; Goberdhan et al., 1999; Huang et al., 1999) have all been shown to regulate cell growth. Although the factors that regulate cell di ...
... importance. For example, the oncogenes Myc, Ras and Cyclin D (Prober and Edgar, 2001) and the tumor suppressors retinoblastoma (White, 1997) and Pten (Gao et al., 2000; Goberdhan et al., 1999; Huang et al., 1999) have all been shown to regulate cell growth. Although the factors that regulate cell di ...
Biology 409 - CSU, Chico
... Compare genomes and offer explanations reflecting current hypotheses for differences in genome size. ...
... Compare genomes and offer explanations reflecting current hypotheses for differences in genome size. ...
Noise in transcription negative feedback loops
... in too high values for the final concentrations of TetR and GFP. Thus, we slightly altered the degradation rates of TetR and GFP in order to have approximately the same final numbers of molecules as found in this study (similar results were obtained if instead we slightly modified the production rates) ...
... in too high values for the final concentrations of TetR and GFP. Thus, we slightly altered the degradation rates of TetR and GFP in order to have approximately the same final numbers of molecules as found in this study (similar results were obtained if instead we slightly modified the production rates) ...
The Arabidopsis NAC Transcription Factor VNI2
... et al., 2010a). The Arabidopsis NAP (NAC-LIKE, ACTIVATED BY AP3/PI) gene is transcriptionally regulated during senescing process in Arabidopsis leaves (Guo and Gan, 2006). Whereas the NAP-deficient mutant exhibits delayed leaf senescence, premature senescence is induced in the transgenic plants over ...
... et al., 2010a). The Arabidopsis NAP (NAC-LIKE, ACTIVATED BY AP3/PI) gene is transcriptionally regulated during senescing process in Arabidopsis leaves (Guo and Gan, 2006). Whereas the NAP-deficient mutant exhibits delayed leaf senescence, premature senescence is induced in the transgenic plants over ...
Special Feature —Manipulating Genes to Understand
... of animal models of human diseases are but two examples of how this technology has affected medical science. Transgenic animals are defined as animals in which a segment of DNA has been physically integrated into the genome of all cells, including the germ line, so that it can be transmitted to offs ...
... of animal models of human diseases are but two examples of how this technology has affected medical science. Transgenic animals are defined as animals in which a segment of DNA has been physically integrated into the genome of all cells, including the germ line, so that it can be transmitted to offs ...
Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.