1 Title: Evidence for large domains of similarly expressed genes in
... These insulators seem to function, not by deactivating cis-modules, but by preventing their influence from being propagated along the chromosome. It is unknown how ...
... These insulators seem to function, not by deactivating cis-modules, but by preventing their influence from being propagated along the chromosome. It is unknown how ...
Drosophila Genetics Simulation
... Genetics is the scientific study of heredity. Scientists substitute simple organisms for humans when studying inherited diseases and disorders. About 60% of the genes that are known to cause human disease have a recognizable match in the genetic code of the common fruit fly (Drosophila melanogaster) ...
... Genetics is the scientific study of heredity. Scientists substitute simple organisms for humans when studying inherited diseases and disorders. About 60% of the genes that are known to cause human disease have a recognizable match in the genetic code of the common fruit fly (Drosophila melanogaster) ...
Structural and Functional Studies of Insertion Element IS200
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
... The nucleotide sequence of the insertion element 15200 has been determined partially, including the junctions between the element and the host chromosome at the insertion site, At most, two bases (A-A) are found repeated at the junctions and could be duplications of host sequences generated by the i ...
Epigenetic inheritance of acquired traits through sperm RNAs and
... paternal germline inheritance could be environmentally induced aberrant DNA methylation patterns that are maintained in the sperm and escape at least two waves of epigenetic reprogramming 13, resulting in the persistence of these patterns in the offspring. Evidence supporting the escape of DNA methy ...
... paternal germline inheritance could be environmentally induced aberrant DNA methylation patterns that are maintained in the sperm and escape at least two waves of epigenetic reprogramming 13, resulting in the persistence of these patterns in the offspring. Evidence supporting the escape of DNA methy ...
Accepted Version - CSIRO Research Publications Repository
... chromatin structure plays an important role in gene expression: Gene expression can be controlled by changes in the structure of chromatin without changing the DNA sequence, and this phenomenon is termed “epigenetic” control. Recently, there have been many reports indicating that epigenetic change c ...
... chromatin structure plays an important role in gene expression: Gene expression can be controlled by changes in the structure of chromatin without changing the DNA sequence, and this phenomenon is termed “epigenetic” control. Recently, there have been many reports indicating that epigenetic change c ...
Bio 125 Lab Week 9: Relating Changes in Form to Changes in Genes
... organized; for today, you can probably keep all your data in one session. To choose a particular session, go to the Preferences page, click the button beside the session you want (at the bottom of the page), and click on the RESUME button. The highlighted session is your current session. 2. In order ...
... organized; for today, you can probably keep all your data in one session. To choose a particular session, go to the Preferences page, click the button beside the session you want (at the bottom of the page), and click on the RESUME button. The highlighted session is your current session. 2. In order ...
Natural variation in nucleolar dominance reveals
... distinct differences in the NOR chromatin organization in interphase nuclei of LC1 and 9502 (Fig. 5). In LC1, A. arenosalike NORs show partial decondensation at interphase, which is manifest in two ways. One manifestation is the appearance of FISH signal spots in excess of the number of NORs because ...
... distinct differences in the NOR chromatin organization in interphase nuclei of LC1 and 9502 (Fig. 5). In LC1, A. arenosalike NORs show partial decondensation at interphase, which is manifest in two ways. One manifestation is the appearance of FISH signal spots in excess of the number of NORs because ...
Книжечка
... 2. The nuclear region directs the activities of the cell. In bacteria, the genetic material is mostly included in a single, closed, circular molecule of DNA, which resides in a central portion of the cell, unbounded by membranes. In eukaryotes, by contrast, a double membrane – the nuclear membrane, ...
... 2. The nuclear region directs the activities of the cell. In bacteria, the genetic material is mostly included in a single, closed, circular molecule of DNA, which resides in a central portion of the cell, unbounded by membranes. In eukaryotes, by contrast, a double membrane – the nuclear membrane, ...
Pdf - Text of NPTEL IIT Video Lectures
... which single stranded D N A that provides the free three prime hydroxyl and required for the D N A replication to start noise. The leading and lagging strands the D N A polymerase can synthesize D N A only in five prime directions to three prime directions. Therefore, it is synthesizes one is strand ...
... which single stranded D N A that provides the free three prime hydroxyl and required for the D N A replication to start noise. The leading and lagging strands the D N A polymerase can synthesize D N A only in five prime directions to three prime directions. Therefore, it is synthesizes one is strand ...
MayerFrankiPoster
... Our group had genetically modified the cyanobacterium Synechococcus sp. PCC 7002 to produce isoprene. However, for this ‘photo-isoprene’ to become a marketable option for replacing petroleum products, there are many more modifications to be made. One of these involves the gene cpcB that codes for a ...
... Our group had genetically modified the cyanobacterium Synechococcus sp. PCC 7002 to produce isoprene. However, for this ‘photo-isoprene’ to become a marketable option for replacing petroleum products, there are many more modifications to be made. One of these involves the gene cpcB that codes for a ...
Genome position and gene amplification | SpringerLink
... oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how expression of an oncogene might be altered. Moreover, amplification is often associated with poor prognosis. Amplification is a reiterative process, in which multiple copies of ...
... oncogenes, suggesting that the particular types of genomic instability present in a tumor are important determinants of how expression of an oncogene might be altered. Moreover, amplification is often associated with poor prognosis. Amplification is a reiterative process, in which multiple copies of ...
Mef2 gene expression marks the cardiac and skeletal muscle
... MEF2 DNA-binding activity is upregulated during differentiation of established muscle cell lines and can be induced in nonmuscle cells by myogenin and MyoD (Cserjesi et al., 1991; Lassar et al., 1991), consistent with the notion that MEF2 lies in a regulatory pathway ‘downstream’ of these myogenic f ...
... MEF2 DNA-binding activity is upregulated during differentiation of established muscle cell lines and can be induced in nonmuscle cells by myogenin and MyoD (Cserjesi et al., 1991; Lassar et al., 1991), consistent with the notion that MEF2 lies in a regulatory pathway ‘downstream’ of these myogenic f ...
GCF (K-13): sc-133418 - Santa Cruz Biotechnology
... GCF (GC-rich sequence DNA-binding factor), also known as C2orf3 (chromosome 2 open reading frame 3), transcription factor 9 (TCF-9) or DNABF, is a 781 amino acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds the GC-rich sequences of β-Actin, EGFR and calciumdependent pr ...
... GCF (GC-rich sequence DNA-binding factor), also known as C2orf3 (chromosome 2 open reading frame 3), transcription factor 9 (TCF-9) or DNABF, is a 781 amino acid nuclear protein that belongs to the GCF family. Widely expressed, GCF binds the GC-rich sequences of β-Actin, EGFR and calciumdependent pr ...
You`re one in a googol: optimizing genes for protein expression
... Yarus 1989; Gutman & Hatfield 1989; Irwin et al. 1995; Boycheva et al. 2003; Moura et al. 2005; Buchan et al. 2006). Finally, and of particular relevance when high levels of heterologous protein are expressed, the concentrations of free amino acids and charged tRNA in the cell could change significant ...
... Yarus 1989; Gutman & Hatfield 1989; Irwin et al. 1995; Boycheva et al. 2003; Moura et al. 2005; Buchan et al. 2006). Finally, and of particular relevance when high levels of heterologous protein are expressed, the concentrations of free amino acids and charged tRNA in the cell could change significant ...
A new FISH protocol with increased sensitivity for
... This study worked on enhancing signal intensity, and within this parameter on optimizing target accessibility, labelling and hybridization conditions. The optimization of the technique was made possible because, under nonoptimal conditions, few spots were detectable and their number and intensity in ...
... This study worked on enhancing signal intensity, and within this parameter on optimizing target accessibility, labelling and hybridization conditions. The optimization of the technique was made possible because, under nonoptimal conditions, few spots were detectable and their number and intensity in ...
BioACTS Quarter THREE
... a nucleic acid is called a nucleotide. Nucleotides are made up of THREE parts—a phosphate group, a sugar (deoxyribose) and one of four nitrogen bases. Diagram I Draw and label ONE nucleotide using the highlighters below your entry task. ...
... a nucleic acid is called a nucleotide. Nucleotides are made up of THREE parts—a phosphate group, a sugar (deoxyribose) and one of four nitrogen bases. Diagram I Draw and label ONE nucleotide using the highlighters below your entry task. ...
The R2R3 MYB Transcription Factor GhMYB109 Is
... Cotton (Gossypium hirsutum L.) fibers are single highly elongated cells derived from the outer epidermis of ovules. A large number of genes are required for fiber differentiation and development, but so far, little is known about how these genes control and regulate the process of fiber development. ...
... Cotton (Gossypium hirsutum L.) fibers are single highly elongated cells derived from the outer epidermis of ovules. A large number of genes are required for fiber differentiation and development, but so far, little is known about how these genes control and regulate the process of fiber development. ...
Glycosylphosphatidyl inositol-anchored protein (GPI
... expressed genes. We validated the differential expression of several of the genes identified through Biochip analysis, by means of quantitative RT-PCR of RNA from 48 thymoma tumors. We found that GPI-80 was significantly higher in invasive thymoma (stage IV thymoma) than in stage I thymoma. It has p ...
... expressed genes. We validated the differential expression of several of the genes identified through Biochip analysis, by means of quantitative RT-PCR of RNA from 48 thymoma tumors. We found that GPI-80 was significantly higher in invasive thymoma (stage IV thymoma) than in stage I thymoma. It has p ...
Complete mitochondrial genome of a natural triploid
... Genome content and organization The total length of the mitochondrial genome was determined to be 16,576 bp with a standard set of 22 tRNAs, 2 rRNAs, and 13 typical vertebrate protein-coding genes, as well as a putative non-coding control region (Figure 1, Table 2). Most of the genes were encoded on ...
... Genome content and organization The total length of the mitochondrial genome was determined to be 16,576 bp with a standard set of 22 tRNAs, 2 rRNAs, and 13 typical vertebrate protein-coding genes, as well as a putative non-coding control region (Figure 1, Table 2). Most of the genes were encoded on ...
Acanthamoeba mitochondrial 16S rDNA sequences: inferred
... culbertsoni Diamond and A. royreba Oak Ridge both had mT4 genotypes. ...
... culbertsoni Diamond and A. royreba Oak Ridge both had mT4 genotypes. ...
PDF
... pCR2.1-ACF1-flag using the Site-directed Mutagenesis Kit (Stratagene). The following pairs of oligonucleotides were used to delete the PHD1 or PHD2, respectively: PHD1F, 5⬘-ACCAATAAGTCATTAGTCGACGTAAAGAGTCTGGGTCTCAGC-3⬘; PHD1R, 5⬘-ACCCAGACTCTTTACGTCGACTAATGACTTATTGGTGGAACGC-3⬘; PHD2F, 5⬘-GATGAGGAAAAG ...
... pCR2.1-ACF1-flag using the Site-directed Mutagenesis Kit (Stratagene). The following pairs of oligonucleotides were used to delete the PHD1 or PHD2, respectively: PHD1F, 5⬘-ACCAATAAGTCATTAGTCGACGTAAAGAGTCTGGGTCTCAGC-3⬘; PHD1R, 5⬘-ACCCAGACTCTTTACGTCGACTAATGACTTATTGGTGGAACGC-3⬘; PHD2F, 5⬘-GATGAGGAAAAG ...
Chromatin dynamics during cellular differentiation in the female
... most animals where meiosis directly produces gametes, plant meiosis entails the differentiation of a multicellular, haploid gametophyte, within which gametic as well as non-gametic accessory cells are formed. These observations raise the question of the factors inducing and modus operandi of cell fa ...
... most animals where meiosis directly produces gametes, plant meiosis entails the differentiation of a multicellular, haploid gametophyte, within which gametic as well as non-gametic accessory cells are formed. These observations raise the question of the factors inducing and modus operandi of cell fa ...
Epigenetic mechanisms regulate placental c-myc
... 2005; Chan et al., 2006), that can be used for physiological pregnancies but there is no known epigenetic marker specific for pathological pregnancies. Based on the previous literature, in this study we analyzed the mRNA expression of c-myc and hTERT in reference to the epigenetic mechanisms of DNA m ...
... 2005; Chan et al., 2006), that can be used for physiological pregnancies but there is no known epigenetic marker specific for pathological pregnancies. Based on the previous literature, in this study we analyzed the mRNA expression of c-myc and hTERT in reference to the epigenetic mechanisms of DNA m ...
Contribution of IKBKE and IFIH1 gene variants to SLE susceptibility
... Figure 1. The IKBKE SNV rs12142086 affects the binding of SF1 with DNA. (a) The SNV rs12142086 is predicted to be located in the binding motif of SF1. Introns are represented by grey horizontal lines and exons by vertical bars with numbers. The position of rs12142086 is highlighted with a star. In t ...
... Figure 1. The IKBKE SNV rs12142086 affects the binding of SF1 with DNA. (a) The SNV rs12142086 is predicted to be located in the binding motif of SF1. Introns are represented by grey horizontal lines and exons by vertical bars with numbers. The position of rs12142086 is highlighted with a star. In t ...
Primary transcript
A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.