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HERE
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File - Wk 1-2
File - Wk 1-2

... products of the cycle and the role of the cycle in providing reducing equivalents for the electron transport chain. The citric acid cycle (Krebs cycle) occurs in the mitacholdria of the cell and occurs in the presence of oxygen (aerobic pathway). Pyruvic acid from glycolysis first needs to be conver ...
BIO121_Chapter 6
BIO121_Chapter 6

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... Glutathione is the main intercellular antioxidant of the liver. Evaluation of the use of glutathione is of great utility when judging liver function. A number of urine markers can help make this evaluation. A low sulfate reveals a need to replenish sulfur containing amino acids. Glutathione administ ...
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Lecture 28 - Citrate Cycle
Lecture 28 - Citrate Cycle

... • The primary function of the citrate cycle is to convert energy available from the oxidization acetyl-CoA into 3 moles of NADH, 1 mole of FADH2 and 1 mole of GTP during each turn of the cycle. • The citrate cycle is a "metabolic engine" in which all eight of the cycle intermediates are continually ...
Unit Title:
Unit Title:

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intermediary metabolism

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... 2. During glycolysis, how many ADP molecules are converted to ATP. Explain this answer with regard to your answer to #1. 4 ADP molecules are converted into ATP. There is a net gain of only 2 ATP molecules because 2 are consumed during the first stage of glycolysis. 3. What are the three metabolicall ...
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PDF

... et al., 2007), which is similar to the 3HOP bi-cycle and uses the same carbon assimilation enzymes (e.g., acetyl-CoA carboxylase and propionyl-CoA carboxylase), the dicarboxylate/4HOB cycle (Huber et al., 2008), and the reductive acetyl-CoA pathway (Ljungdahl, 1986; Wood, 1991) have not yet been rep ...
PDF
PDF

... et al., 2007), which is similar to the 3HOP bi-cycle and uses the same carbon assimilation enzymes (e.g., acetyl-CoA carboxylase and propionyl-CoA carboxylase), the dicarboxylate/4HOB cycle (Huber et al., 2008), and the reductive acetyl-CoA pathway (Ljungdahl, 1986; Wood, 1991) have not yet been rep ...
ATP Synthesis
ATP Synthesis

... In the so-called “binding change” mechanism, each of the three αβ catalytic protomers of the α3β3 subunits of F1 component is envisioned to adopt three distinct conformations designated O, L and T that are in equilibrium exchange with each other: O  catalytically-inactive / low affinity for ligands ...
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Molecular Biology of the Cell

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Microbial metabolism



Microbial metabolism is the means by which a microbe obtains the energy and nutrients (e.g. carbon) it needs to live and reproduce. Microbes use many different types of metabolic strategies and species can often be differentiated from each other based on metabolic characteristics. The specific metabolic properties of a microbe are the major factors in determining that microbe’s ecological niche, and often allow for that microbe to be useful in industrial processes or responsible for biogeochemical cycles.== Types of microbial metabolism ==All microbial metabolisms can be arranged according to three principles:1. How the organism obtains carbon for synthesising cell mass: autotrophic – carbon is obtained from carbon dioxide (CO2) heterotrophic – carbon is obtained from organic compounds mixotrophic – carbon is obtained from both organic compounds and by fixing carbon dioxide2. How the organism obtains reducing equivalents used either in energy conservation or in biosynthetic reactions: lithotrophic – reducing equivalents are obtained from inorganic compounds organotrophic – reducing equivalents are obtained from organic compounds3. How the organism obtains energy for living and growing: chemotrophic – energy is obtained from external chemical compounds phototrophic – energy is obtained from lightIn practice, these terms are almost freely combined. Typical examples are as follows: chemolithoautotrophs obtain energy from the oxidation of inorganic compounds and carbon from the fixation of carbon dioxide. Examples: Nitrifying bacteria, Sulfur-oxidizing bacteria, Iron-oxidizing bacteria, Knallgas-bacteria photolithoautotrophs obtain energy from light and carbon from the fixation of carbon dioxide, using reducing equivalents from inorganic compounds. Examples: Cyanobacteria (water (H2O) as reducing equivalent donor), Chlorobiaceae, Chromatiaceae (hydrogen sulfide (H2S) as reducing equivalent donor), Chloroflexus (hydrogen (H2) as reducing equivalent donor) chemolithoheterotrophs obtain energy from the oxidation of inorganic compounds, but cannot fix carbon dioxide (CO2). Examples: some Thiobacilus, some Beggiatoa, some Nitrobacter spp., Wolinella (with H2 as reducing equivalent donor), some Knallgas-bacteria, some sulfate-reducing bacteria chemoorganoheterotrophs obtain energy, carbon, and reducing equivalents for biosynthetic reactions from organic compounds. Examples: most bacteria, e. g. Escherichia coli, Bacillus spp., Actinobacteria photoorganoheterotrophs obtain energy from light, carbon and reducing equivalents for biosynthetic reactions from organic compounds. Some species are strictly heterotrophic, many others can also fix carbon dioxide and are mixotrophic. Examples: Rhodobacter, Rhodopseudomonas, Rhodospirillum, Rhodomicrobium, Rhodocyclus, Heliobacterium, Chloroflexus (alternatively to photolithoautotrophy with hydrogen)
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