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Muddashetty RS, Nalavadi VC, Gross C, Yao X, Xing L, Laur O, Warren ST, and Bassell GJ. Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling. Molecular Cell 42: 673-688 (June 2011).
Muddashetty RS, Nalavadi VC, Gross C, Yao X, Xing L, Laur O, Warren ST, and Bassell GJ. Reversible Inhibition of PSD-95 mRNA Translation by miR-125a, FMRP Phosphorylation, and mGluR Signaling. Molecular Cell 42: 673-688 (June 2011).

... from neurons stimulated with DHPG (Figure 1B). A similar DHPGinduced decrease in the association with AGO2 was also observed for endogenous PSD-95 mRNA (61% ± 20%) (Figure 1B), while endogenous b-actin mRNA was unaffected (see Figure S1C available online). Treatment with DHPG had no apparent effect ...
Steroid Hormone Induction Of Temporal Gene Expression
Steroid Hormone Induction Of Temporal Gene Expression

... that larvae express Cas and Svp in type I or type II neuroblasts prior to 48h (timing is relative to larval hatching ...
In vivo quantification of peroxisome tethering to chloroplasts in
In vivo quantification of peroxisome tethering to chloroplasts in

... 2008; Sparkes et al., 2008). Tubular emanations termed peroxules (Scott et al., 2007) ...
PDF
PDF

... of nitrification, play an important role in biological wastewater treatment systems. Nitrosomonas mobilis is an important and dominant AOB in various wastewater treatment systems. However, the detailed physiological and genomic properties of N. mobilis have not been thoroughly investigated because o ...
Novel leader exons of the cyclic adenosine 3 ,5
Novel leader exons of the cyclic adenosine 3 ,5

... expression pattern is very similar between the rodent and the primate testis (Behr and Weinbauer, 1999). CREM expression attains peak levels in those stages associated with the formation of the acrosome (Russell et al., 1990), and vanishes at the initiation of nuclear elongation. CREM expression has ...
Mitochondrial trafficking and anchoring in neurons
Mitochondrial trafficking and anchoring in neurons

... Correspondence to Zu-Hang Sheng: [email protected] Abbreviations used in this paper: KIF5, kinesin-1 family; MT, microtubule. ...
Analysis of exocyst subunit EXO70 family reveals
Analysis of exocyst subunit EXO70 family reveals

... We previously discovered the exocyst complex in plants (Eliáš et al., 2003) and have unraveled some of its functions like pectin deposition in seed coats (Kulich et al., 2010), recycling of auxin transporters (Drdová EJ et al., 2013), cell plate initiation and maturation during cytokinesis (Fendrych ...
pdf file - John Innes Centre
pdf file - John Innes Centre

... greatest in nitrogen-sufficient conditions (14). These data suggested that GlnK bound to AmtB when the cellular nitrogen status reached a certain level, so as to inhibit further ammonium transport. In this paper we now demonstrate that the two proteins do indeed form a complex. To be of physiologica ...
VegT initiates mesoderm induction - Development
VegT initiates mesoderm induction - Development

... has been challenged, however, by two recent observations. Firstly, heterochronic Nieuwkoop recombination experiments indicate that vegetal cells are competent to induce mesodermal tissue only after the mid-blastula transition, not before zygotic ...
Roles of Arabidopsis PARC6 in Coordination of
Roles of Arabidopsis PARC6 in Coordination of

... well as to test the interactions with and effects of putative FtsZ assembly regulators (Srinivasan et al., 2007, 2008; TerBush and Osteryoung, 2012; Zhang et al., 2013). When expressed alone in S. pombe, PARC677-573mCherry fluorescence appeared diffusely localized in the cytosol (Fig. 3A), similar to ...
Minireview: Lipid Droplets in Lipogenesis and Lipolysis
Minireview: Lipid Droplets in Lipogenesis and Lipolysis

... ATGL, adipocyte triglyceride lipase; CDS, Chanarin-Dorfman syndrome; CGI-58, Comparative Gene Identification-58; DAG, diacylglycerol; ER, endoplasmic reticulum; GLUT4, glucose transporter 4; HSL, hormone-sensitive lipase; LSDP5, lipid storage droplet protein 5; MLDP, ...
Mechanical motion promotes expression of Prg4
Mechanical motion promotes expression of Prg4

Macrophages from Vacuoles in Activated monocytogenes Listeria
Macrophages from Vacuoles in Activated monocytogenes Listeria

... macrophage by phagocytosis. During a successful infection, Lm perforates the membranous vacuole that contains it and escapes into the macrophage cytoplasm. There it can grow, divide, and eventually nucleate host cell actin in a process that facilitates transfer to neighboring cells (1). However, if ...
Jelena Raspopovic Molecular basis for digit patterning in the vertebrate limb
Jelena Raspopovic Molecular basis for digit patterning in the vertebrate limb

... 1.1.7) Experimental evidence for the Positional Information model. .................... 15 1.1.8) Turing model versus Positional Information model. .................................... 17 1.2 Mouse limb development: a model system for patterning and morphogenesis ... 18 1.2.1) Anatomy of the skeleta ...
Concomitant appearance of intrinsic
Concomitant appearance of intrinsic

... of isogenic diploid 5. cerevisiae strains was generated to facilitate further testing of whether trehalose functions in intrinsic stress tolerance. Both isogenic strains inherited a partially reverted c i f l phenotype, designated CPR, from the trehalose-deficient progenitor that had been used in co ...
Muscle length and myonuclear position are
Muscle length and myonuclear position are

... have studied the role of Dynein during muscle morphogenesis in Drosophila. We establish muscle length, which is an aspect of muscle size, and myonuclear positioning as independent aspects of muscle morphogenesis. We further show that the microtubule cytoskeleton contributes to both processes. Specif ...
Week 5 Day 2
Week 5 Day 2

... Some members of the pumpkin family produce roots capable of storing large amounts of water. Some of these roots have a mass of about 30 kg. In which type of environment are these plants most likely found? F Aquatic G Dry H Cold J Humid ...
PureLink® RNA Mini Kit - Thermo Fisher Scientific
PureLink® RNA Mini Kit - Thermo Fisher Scientific

... For expected RNA yields of 100 μg or less, perform one elution using 30–100 μL RNase–Free Water or Tris buffer. For large samples and for expected RNA yields >100 μg, perform sequential 100 μL elutions on your sample using RNase-Free Water or Tris buffer. For example, to obtain RNA yields of 100–500 ...
thesis - BORA
thesis - BORA

... with sclerotomal origin. The nucleation and growth pattern of hydroxyapatite crystals were similar in both type I and type II collagen matrices. The crystals always grew as thin flakes along the long axis of the collagen fibrils, while the production of major collagen transcripts significantly decr ...
Lesions of and Surgical Approaches to the Petrous Apex
Lesions of and Surgical Approaches to the Petrous Apex

... 4-7% of pneumatized apices are asymmetrical ...
Spatial Reorganization of Glycogen Synthase upon Activation in 3T3
Spatial Reorganization of Glycogen Synthase upon Activation in 3T3

... the activation of glycogen synthase in a variety of cell types (reviewed in Ref. 1). To investigate whether the insulininduced glycogen synthase redistribution in 3T3-L1 adipocytes required increased glucose utilization, extracellular glucose conditions were varied. 3T3-L1 adipocytes were seeded on ...
Roles of Long Non-coding RNAs in X
Roles of Long Non-coding RNAs in X

... repeated sequence at its 50 end (Grant et al. 2012). This apparent functional conservation without sequence similarity suggests that ncRNA-mediated regulation of dosage compensation arose at least twice during mammalian evolution, highlighting the general utility of this regulatory strategy for the ...
Thermogenesis in Muscle
Thermogenesis in Muscle

... production independent of contractile activity usually focus on mammals where extensive reviews exist (44, 46, 47, 83, 86, 95). Despite major efforts to understand howmuscle contributes to basal metabolic rate (BMR) and to cold-induced thermogenesis in endotherms, the mechanistic basis of such activ ...
The Copper Efflux Regulator CueR Is Subject to ATP
The Copper Efflux Regulator CueR Is Subject to ATP

... homeostasis (Lu and Solioz, 2001; Solioz, 2002; Lu et al., 2003; Solioz and Stoyanov, 2003; Liu et al., 2007; Pruteanu et al., 2007; Pruteanu and Baker, 2009). Regulated proteolysis is a universal post-translational strategy adapting the existing protein pool to the cellular demand. In E. coli five ...
The intercalated disc-associated Xin family of proteins in cardiac
The intercalated disc-associated Xin family of proteins in cardiac

... leads to cardiac morphological defects, diastolic dysfunction and heart failure, which lead to severe growth retardation and early postnatal lethality. I also showed that mXinβ might be involved in a number of cell signaling pathways and provide multiple lines of evidence to support mXinβ’s roles in ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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