The G-protein regulator LGN modulates the activity of the NO
... (soluble guanylate cyclase) (also called GTP pyrophosphatelyase). These effects include regulation of smooth muscle cell relaxation, neurotransmission, platelet function, mitochondrial biogenesis and cell proliferation [1,2]. sGC converts GTP into the second messenger cGMP, resulting in activation o ...
... (soluble guanylate cyclase) (also called GTP pyrophosphatelyase). These effects include regulation of smooth muscle cell relaxation, neurotransmission, platelet function, mitochondrial biogenesis and cell proliferation [1,2]. sGC converts GTP into the second messenger cGMP, resulting in activation o ...
estrogen receptor by cyclin D1 Ligand
... Cyclin D1 is induced in response to mitogenic stimulation of quiescent cells and acts as an activator of CDK4 and CDK6. These cyclin D1/CDK complexes are key regulators of progression through the G1 phase of the cell cycle and are involved in functional inactivation of the retinoblastoma family prot ...
... Cyclin D1 is induced in response to mitogenic stimulation of quiescent cells and acts as an activator of CDK4 and CDK6. These cyclin D1/CDK complexes are key regulators of progression through the G1 phase of the cell cycle and are involved in functional inactivation of the retinoblastoma family prot ...
Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function
... purified ManLAM was efficiently bound by DC-SIGN, in contrast to AraLAM (Fig. 1 c), demonstrating that DCSIGN specifically interacts with the mono-, di-, and trimers of -d-mannoses of ManLAM. Even at high concentrations, DC-SIGN did not bind AraLAM, demonstrating a high specificity for ManLAM and i ...
... purified ManLAM was efficiently bound by DC-SIGN, in contrast to AraLAM (Fig. 1 c), demonstrating that DCSIGN specifically interacts with the mono-, di-, and trimers of -d-mannoses of ManLAM. Even at high concentrations, DC-SIGN did not bind AraLAM, demonstrating a high specificity for ManLAM and i ...
Self-Incompatibility-induced Programmed Cell
... Robinson, 1998). There has been much debate about the cytosolic pH gradient, comprising an apical domain ~pH 6.8 and a subapical alkaline band ~pH 7.2 to 7.8 in lily pollen tubes (Fricker et al., 1997; Messerli and Robinson, 1998; Feijo et al., 2001; Lovy-Wheeler et al., 2006). Oscillations of [pH] ...
... Robinson, 1998). There has been much debate about the cytosolic pH gradient, comprising an apical domain ~pH 6.8 and a subapical alkaline band ~pH 7.2 to 7.8 in lily pollen tubes (Fricker et al., 1997; Messerli and Robinson, 1998; Feijo et al., 2001; Lovy-Wheeler et al., 2006). Oscillations of [pH] ...
Short- and long-range functions of Goosecoid in
... of the organizer is to repress factors secreted from ventral regions of the embryo (Niehrs, 2004). Secreted ventralizing factors of the BMP, Wnt and Nodal families function in gradients in the early embryo and organizer-derived molecules attenuate the activity of these factors (Niehrs, 2004). Ventra ...
... of the organizer is to repress factors secreted from ventral regions of the embryo (Niehrs, 2004). Secreted ventralizing factors of the BMP, Wnt and Nodal families function in gradients in the early embryo and organizer-derived molecules attenuate the activity of these factors (Niehrs, 2004). Ventra ...
ERROR-PRONE REPAIR DNA POLYMERASES IN PROKARYOTES
... do exhibit error-prone behavior. These polymerases include the four founding Y-family members and their human homologs, along with errant fellow travelers such as pol , an enzyme that prefers to incorporate G rather than A opposite T. We also describe the properties of several repair polymerases th ...
... do exhibit error-prone behavior. These polymerases include the four founding Y-family members and their human homologs, along with errant fellow travelers such as pol , an enzyme that prefers to incorporate G rather than A opposite T. We also describe the properties of several repair polymerases th ...
Physiology and molecular biology of petal senescence
... contents, and might therefore be due to ongoing remobilization, but might also occur independently of the remobilization process. Several factors that control programmed death of animal cells, such as caspases, proteins released by mitochondria, and proteins that control the release of compounds thr ...
... contents, and might therefore be due to ongoing remobilization, but might also occur independently of the remobilization process. Several factors that control programmed death of animal cells, such as caspases, proteins released by mitochondria, and proteins that control the release of compounds thr ...
EIR 18 - Universitätsklinikum Tübingen
... This year´s issue of EIR contains eight scientific articles, six of which are concerned with Exercise Immunology itself while the last two have a decidedly clinical orientation. We would love to see this latter part increase a bit in future issues of EIR. It must however be acknowledged that all of ...
... This year´s issue of EIR contains eight scientific articles, six of which are concerned with Exercise Immunology itself while the last two have a decidedly clinical orientation. We would love to see this latter part increase a bit in future issues of EIR. It must however be acknowledged that all of ...
Assessing the Flexibility of Intermediate Filaments by Atomic Force
... M.E. Müller Institute for Structural Biology Biozentrum, University of Basel, Klingelbergstr. 70 4056 Basel, Switzerland ...
... M.E. Müller Institute for Structural Biology Biozentrum, University of Basel, Klingelbergstr. 70 4056 Basel, Switzerland ...
Auxin transport – shaping the plant
... Two theoretical concepts have greatly in¯uenced the way that we think about auxin and its action: the concepts of a hormones and a morphogen. The mammalian hormone concept de®nes hormones as extracellular signaling molecules, which act on target cells distant from their localized site of synthesis [ ...
... Two theoretical concepts have greatly in¯uenced the way that we think about auxin and its action: the concepts of a hormones and a morphogen. The mammalian hormone concept de®nes hormones as extracellular signaling molecules, which act on target cells distant from their localized site of synthesis [ ...
Author`s post-print - Cardiff Metropolitan University
... Medihoney™ on existing biofilm (Fig. 2a) because both bacteria dispersed from the biofilm and adherent bacteria contributed to density. ...
... Medihoney™ on existing biofilm (Fig. 2a) because both bacteria dispersed from the biofilm and adherent bacteria contributed to density. ...
Arabidopsis VILLIN4 is involved in root hair growth through
... cells (Klahre et al., 2000). The full length of AtVLN3 and the headpiece domains of AtVLN1 to AtVLN3, when fused with green fluorescent protein (GFP), decorate actin filaments in plant and animal cells, thus demonstrating that these AtVLNs bind to actin filaments in vivo (Klahre et al., 2000). The b ...
... cells (Klahre et al., 2000). The full length of AtVLN3 and the headpiece domains of AtVLN1 to AtVLN3, when fused with green fluorescent protein (GFP), decorate actin filaments in plant and animal cells, thus demonstrating that these AtVLNs bind to actin filaments in vivo (Klahre et al., 2000). The b ...
![[pdf]](http://s1.studyres.com/store/data/008788365_1-2fc4648a6271254a8daa6f8a037dd81c-300x300.png)
[pdf]
... are less dramatic but similar to those observed after injection of a dominant-negative mutant of the APC/C-specific E2, UbcH10C114S. By contrast, overexpression or injection of WT ubiquitin does not affect the degradation of APC/C substrates, progression through the cell cycle, or development of emb ...
... are less dramatic but similar to those observed after injection of a dominant-negative mutant of the APC/C-specific E2, UbcH10C114S. By contrast, overexpression or injection of WT ubiquitin does not affect the degradation of APC/C substrates, progression through the cell cycle, or development of emb ...
Mouse Embryology Module, Woods Hole 2010
... Alcian Blue does not readily dissolve in 70% ETOH, but does dissolve in 50% ETOH. To make 100 ml of 0.4% Alcian Blue stock, add 0.4g Alcian Blue to 10 ml 50% ETOH in a 250 ml bottle. Swirl and place in 37°C water bath. Swirl occasionally. When dissolved, add 25 ml water and 65 ml 95% ...
... Alcian Blue does not readily dissolve in 70% ETOH, but does dissolve in 50% ETOH. To make 100 ml of 0.4% Alcian Blue stock, add 0.4g Alcian Blue to 10 ml 50% ETOH in a 250 ml bottle. Swirl and place in 37°C water bath. Swirl occasionally. When dissolved, add 25 ml water and 65 ml 95% ...
O A RIGINAL RTICLES
... has been observed following a lengthy intake of antibiotics or in the case of diarrhea. This can result in a reduction of the protective functions of these substances for the body. In order to obtain a regular absorption of isoflavones, the intake isoflavones rich foods or isoflavones supplements mu ...
... has been observed following a lengthy intake of antibiotics or in the case of diarrhea. This can result in a reduction of the protective functions of these substances for the body. In order to obtain a regular absorption of isoflavones, the intake isoflavones rich foods or isoflavones supplements mu ...
A Receptor-Like Kinase Mediates Ammonium
... Institute of Plant Stress Biology, State Key Laboratory of Cotton Biology, Department of Biology, Henan University, Kaifeng 475001, China ...
... Institute of Plant Stress Biology, State Key Laboratory of Cotton Biology, Department of Biology, Henan University, Kaifeng 475001, China ...
1 Ratio of mutant JAK2-V617F to wild type Jak2 determines the MPD
... JAK2-V617F mutation could represent the primary causative lesion in MPD. While the JAK2-V617F mutation is found in approximately 95% of patients with polycythemia vera (PV), it is also detectable in about 50% of patient with primary myelofibrosis (PMF) and essential thrombocythemia (ET).2,5 It remai ...
... JAK2-V617F mutation could represent the primary causative lesion in MPD. While the JAK2-V617F mutation is found in approximately 95% of patients with polycythemia vera (PV), it is also detectable in about 50% of patient with primary myelofibrosis (PMF) and essential thrombocythemia (ET).2,5 It remai ...
Human Eosinophils from Transport-Mediated Release of Preformed
... 4) brefeldin A (0.1 and 1 g/ml; Biomol, Plymouth Meeting, PA). Statis- ...
... 4) brefeldin A (0.1 and 1 g/ml; Biomol, Plymouth Meeting, PA). Statis- ...
Barley Aleurone Cells Contain Two Types of
... Figure 1 shows that barley aleurone cells contain protein storage vacuoles and a distinctly different kind of organelle, which we have called secondary vacuoles. Differential interference contrast (DIC) microscopy showed that these two types of vacuole occur in both GA- and ABA-treated aleurone prot ...
... Figure 1 shows that barley aleurone cells contain protein storage vacuoles and a distinctly different kind of organelle, which we have called secondary vacuoles. Differential interference contrast (DIC) microscopy showed that these two types of vacuole occur in both GA- and ABA-treated aleurone prot ...
Endoplasmic reticulum localization of the low density lipoprotein
... initiated in the secretory pathway. Here, we evaluated the ability of several LDLR variants that are stalled within the secretory pathway to regulate apoB secretion. Both a naturally occurring mutant LDLR and an LDLR consisting of only the ligand-binding domains and a C-terminal endoplasmic reticulu ...
... initiated in the secretory pathway. Here, we evaluated the ability of several LDLR variants that are stalled within the secretory pathway to regulate apoB secretion. Both a naturally occurring mutant LDLR and an LDLR consisting of only the ligand-binding domains and a C-terminal endoplasmic reticulu ...
The functional relationship between ectodermal and mesodermal
... ectoteloblasts, while others do not. Moreover, the number of ectoteloblasts varies between species. Conservation of mesoderm segmentation is consistent with a critical developmental function, such as providing an instructive signal to the segmental ectoderm. To test the hypothesis that the mesoderm ...
... ectoteloblasts, while others do not. Moreover, the number of ectoteloblasts varies between species. Conservation of mesoderm segmentation is consistent with a critical developmental function, such as providing an instructive signal to the segmental ectoderm. To test the hypothesis that the mesoderm ...
Discrete Domains Mediate the Light-Responsive
... and DET1, which are nuclear-targeted proteins whose interactions with the COP9-containing complex remain to be resolved (Pepper et al., 1994; von Arnim and Deng, 1994). Overexpression of the COP1 protein in transgenic Arabidopsis induces features of the etiolation pathway under light conditions, mos ...
... and DET1, which are nuclear-targeted proteins whose interactions with the COP9-containing complex remain to be resolved (Pepper et al., 1994; von Arnim and Deng, 1994). Overexpression of the COP1 protein in transgenic Arabidopsis induces features of the etiolation pathway under light conditions, mos ...
Investigations on Mitochondrial Pleomorphy and
... fluctuations in light, sugar and O2. Light and sugar are shown to induce fission whereas a greento-red photo-convertible mEos fluorescent protein targeted to mitochondria (mitoEos) reveals that hypoxia induces fusion, leading to giant mitochondria. The endoplasmic reticulum (ER) is shown to be a med ...
... fluctuations in light, sugar and O2. Light and sugar are shown to induce fission whereas a greento-red photo-convertible mEos fluorescent protein targeted to mitochondria (mitoEos) reveals that hypoxia induces fusion, leading to giant mitochondria. The endoplasmic reticulum (ER) is shown to be a med ...
1 - The Mostowy Lab
... Non-canonical autophagy is a new and developing concept, and can be characterized by features that are different from those in canonical autophagy [3]. In particular, non-canonical autophagy is: A mechanism in which the double-membraned autophagosome does not require all of the ATG proteins to for ...
... Non-canonical autophagy is a new and developing concept, and can be characterized by features that are different from those in canonical autophagy [3]. In particular, non-canonical autophagy is: A mechanism in which the double-membraned autophagosome does not require all of the ATG proteins to for ...
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... nothing was known of cell volume regulation in oocytes before fertilization. We show here that GLYT1 is quiescent in mouse germinal-vesicle-stage oocytes but becomes fully activated within hours after ovulation is triggered. This initiates accumulation of substantial amounts of intracellular glycine ...
... nothing was known of cell volume regulation in oocytes before fertilization. We show here that GLYT1 is quiescent in mouse germinal-vesicle-stage oocytes but becomes fully activated within hours after ovulation is triggered. This initiates accumulation of substantial amounts of intracellular glycine ...