375 Na+/Ca2+ ANTIPORT IN THE MAMMALIAN HEART
... The reasons for the existence of tissue-specific isoforms are uncertain, especially since the kinetic properties of the antiporter are not likely to be affected by alterations in the hydrophilic domain (Matsuoka et al. 1993). However, as discussed below, interactions with the cytoskeleton may be imp ...
... The reasons for the existence of tissue-specific isoforms are uncertain, especially since the kinetic properties of the antiporter are not likely to be affected by alterations in the hydrophilic domain (Matsuoka et al. 1993). However, as discussed below, interactions with the cytoskeleton may be imp ...
Spectrin functions upstream of ankyrin in a spectrin cytoskeleton
... 2004c). From these results, the authors concluded that ankyrin was upstream of spectrin in the spectrin cytoskeleton assembly pathway and that its function was independent of spectrin. However, a study of βIV spectrin knockout mice revealed that βIV spectrin and ankyrin-G are dependent on one anothe ...
... 2004c). From these results, the authors concluded that ankyrin was upstream of spectrin in the spectrin cytoskeleton assembly pathway and that its function was independent of spectrin. However, a study of βIV spectrin knockout mice revealed that βIV spectrin and ankyrin-G are dependent on one anothe ...
The role of c-di-GMP signaling in an Aeromonas veronii biovar
... niches (hospital sewage water, lagoon where duckweed is grown for sewage water purification, fish culture pond where sewage-grown duckweed was used as fish feed and control environmental pond). MT-G was not only detected 2007 Federation of European Microbiological Societies Published by Blackwell Pu ...
... niches (hospital sewage water, lagoon where duckweed is grown for sewage water purification, fish culture pond where sewage-grown duckweed was used as fish feed and control environmental pond). MT-G was not only detected 2007 Federation of European Microbiological Societies Published by Blackwell Pu ...
Evaluating rRNA as an indicator of microbial activity in
... breaks down altogether. For example, the relationship between growth rate and rRNA content is not linear or consistent across all measured growth rates. Under balanced growth conditions, Synechococcus and Prochlorococcus strains can have a three-phase relationship between growth and rRNA concentrati ...
... breaks down altogether. For example, the relationship between growth rate and rRNA content is not linear or consistent across all measured growth rates. Under balanced growth conditions, Synechococcus and Prochlorococcus strains can have a three-phase relationship between growth and rRNA concentrati ...
Regulation of reactive oxygen species homeostasis
... that AHK3 and ARR2 mediate t-Z- and flg22-induced ROS accumulation in guard cells. We also observed higher levels of ROS in guard cells of IPT3 and ARR2 overexpression lines as compared to Col-0 WT (Figure 3B and Supplemental Figure 3A), which could explain their constitutive closed stomata phenotyp ...
... that AHK3 and ARR2 mediate t-Z- and flg22-induced ROS accumulation in guard cells. We also observed higher levels of ROS in guard cells of IPT3 and ARR2 overexpression lines as compared to Col-0 WT (Figure 3B and Supplemental Figure 3A), which could explain their constitutive closed stomata phenotyp ...
Calcium Oscillations and its Functional Significance in
... DNA cleavage and contribute to cell killing80, Uncontrolled steady-state rise of [Ca2+]i can also induce Ca2+dependent activation of several genes that characterize many types of acute lethal injury. These genes can be induced within 15 min or less, as in the case of c-fos66 and c-jun, to trigger ad ...
... DNA cleavage and contribute to cell killing80, Uncontrolled steady-state rise of [Ca2+]i can also induce Ca2+dependent activation of several genes that characterize many types of acute lethal injury. These genes can be induced within 15 min or less, as in the case of c-fos66 and c-jun, to trigger ad ...
Regulation of Nerve Growth Factor Receptor Gene Expression by
... postnatal days 2-11, and isolated RNA from the superior cervical ganglia (SCG) at postnatal day 12. Northern blot analysis revealed that levels of NGF receptor mRNA increased 5-10-fold relative to total RNA synthesis in NGF-treated versus control SCG (Fig. 1 a). No significant differences were obser ...
... postnatal days 2-11, and isolated RNA from the superior cervical ganglia (SCG) at postnatal day 12. Northern blot analysis revealed that levels of NGF receptor mRNA increased 5-10-fold relative to total RNA synthesis in NGF-treated versus control SCG (Fig. 1 a). No significant differences were obser ...
Donohoe, B.S., B. - University of Colorado-MCDB
... is actively producing COPII buds and vesicles for export to the Golgi. To this end, budding COPII vesicles are born within a 40 nm thick scaffold layer that contains Atp115 (Arabidopsis ortholog of p115/Uso1) and appears to have an affinity for the cis-side of the Golgi-encompassing Golgi scaffold/m ...
... is actively producing COPII buds and vesicles for export to the Golgi. To this end, budding COPII vesicles are born within a 40 nm thick scaffold layer that contains Atp115 (Arabidopsis ortholog of p115/Uso1) and appears to have an affinity for the cis-side of the Golgi-encompassing Golgi scaffold/m ...
Evidence for chloroplast control of external Ca -induced
... transit peptide were fused to the GFP protein and expressed transiently in Arabidopsis protoplasts. Confocal microscopy revealed co-localization of GFP fluorescence with chlorophyll autofluorescence in chloroplasts (Figure 2a), suggesting that the N-terminal sequence of CAS acts as a chloroplast tra ...
... transit peptide were fused to the GFP protein and expressed transiently in Arabidopsis protoplasts. Confocal microscopy revealed co-localization of GFP fluorescence with chlorophyll autofluorescence in chloroplasts (Figure 2a), suggesting that the N-terminal sequence of CAS acts as a chloroplast tra ...
Aalborg Universitet AVP-induced increase in AQP2 and p
... Heart failure (HF) is associated with activation of the renin-angiotensin system (RAS) and sustained increased vasopressin (AVP) release from the pituitary gland [1–5]. RAS and AVP have been shown to play a role in the kidneys by taking part in the development of hyponatremia and water retention. Hy ...
... Heart failure (HF) is associated with activation of the renin-angiotensin system (RAS) and sustained increased vasopressin (AVP) release from the pituitary gland [1–5]. RAS and AVP have been shown to play a role in the kidneys by taking part in the development of hyponatremia and water retention. Hy ...
Epithelium and mucus
... bacteria, making it a protective barrier for the enormous bacterial load. The mucus is through this mechanism a part of the innate immunity to keep the homeostasis in colon. The protective function of mucus argues for that defects in the mucus can be a cause of inflammation. In fact, mice with the M ...
... bacteria, making it a protective barrier for the enormous bacterial load. The mucus is through this mechanism a part of the innate immunity to keep the homeostasis in colon. The protective function of mucus argues for that defects in the mucus can be a cause of inflammation. In fact, mice with the M ...
Figure 17. Ptc1 expression in Tulp3 mutant limb buds
... 4.3 Analysis of limb patterning in Tulp3-/- embryos .................................................................. 93 4.3.1 Loss of Tulp3 affects formation of the ZPA but the AER appears intact ..................... 93 4.3.2 Altered A-P patterning of the autopod in Tulp3 mutant limb buds........ ...
... 4.3 Analysis of limb patterning in Tulp3-/- embryos .................................................................. 93 4.3.1 Loss of Tulp3 affects formation of the ZPA but the AER appears intact ..................... 93 4.3.2 Altered A-P patterning of the autopod in Tulp3 mutant limb buds........ ...
Identification of proteins localized to the contractile vacuole of
... bloodstream, acidic phagolysosomes, and host cell cytosol. Thus, the parasites have mechanisms to respond to both hypo-osmotic and hyper-osmotic stresses. The contractile vacuole complex is an osmoregulatory organelle, which controls intracellular water balance by accumulating excess water and expel ...
... bloodstream, acidic phagolysosomes, and host cell cytosol. Thus, the parasites have mechanisms to respond to both hypo-osmotic and hyper-osmotic stresses. The contractile vacuole complex is an osmoregulatory organelle, which controls intracellular water balance by accumulating excess water and expel ...
Penetration of human skin by the cercariae of
... penetration (Wilson & Lawson, 1980; Wilson, 1987; Wilson et al., 1990; Fusco et al., 1993). Results from these experiments cannot, however, be directly extrapolated to the events that occur on the surface of human skin, because the skin of other mammals is very different from human skin in terms of ...
... penetration (Wilson & Lawson, 1980; Wilson, 1987; Wilson et al., 1990; Fusco et al., 1993). Results from these experiments cannot, however, be directly extrapolated to the events that occur on the surface of human skin, because the skin of other mammals is very different from human skin in terms of ...
Superinfection Exclusion by P22 Prophage in Lysogens of Salmonella typhimurium. II. Genetic Evidence for Two Exclusion Systems.
... only if the cultures are started by inoculation with colonies taken from solid media; if liquid cultures are serially subcultured, they rapidly accumulate high levels of free phage, many of which are clear-plaque, virulent mutants. These virulent mutants apparently arise during growth of the primary ...
... only if the cultures are started by inoculation with colonies taken from solid media; if liquid cultures are serially subcultured, they rapidly accumulate high levels of free phage, many of which are clear-plaque, virulent mutants. These virulent mutants apparently arise during growth of the primary ...
Aalborg Universitet
... Heart failure (HF) is associated with activation of the renin-angiotensin system (RAS) and sustained increased vasopressin (AVP) release from the pituitary gland [1–5]. RAS and AVP have been shown to play a role in the kidneys by taking part in the development of hyponatremia and water retention. Hy ...
... Heart failure (HF) is associated with activation of the renin-angiotensin system (RAS) and sustained increased vasopressin (AVP) release from the pituitary gland [1–5]. RAS and AVP have been shown to play a role in the kidneys by taking part in the development of hyponatremia and water retention. Hy ...
PDF Version - Weizmann Institute of Science
... the earliest stages of embryogenesis. Lines with ubiquitous Cre activity will be also useful to process transgenic or targeted mutations by genetic crosses instead of in vitro transfection. This is an advantage, because protracted culture endangers the pluripotentiality of recombinant ES cells and d ...
... the earliest stages of embryogenesis. Lines with ubiquitous Cre activity will be also useful to process transgenic or targeted mutations by genetic crosses instead of in vitro transfection. This is an advantage, because protracted culture endangers the pluripotentiality of recombinant ES cells and d ...
C-terminal processing of yeast Spt7 occurs in the absence of
... export machinery [35] suggesting that SAGA may have a broader role in nuclear processes than previously envisioned. Two forms of Spt7 have been described. The full-length protein of 1332 amino acid residues is found within the SAGA complex [2]. The second, a C-terminally truncated form likely arisin ...
... export machinery [35] suggesting that SAGA may have a broader role in nuclear processes than previously envisioned. Two forms of Spt7 have been described. The full-length protein of 1332 amino acid residues is found within the SAGA complex [2]. The second, a C-terminally truncated form likely arisin ...
Liposomal Formulations for Nucleic Acid Delivery
... Liposomes have received attention not only for their utility as model membrane systems, but also for use in drug delivery. Typically, liposomes are used as drug carriers, with the solubilized drug encapsulated in the internal aqueous space formed by the liposomal lamellae. Liposomal drug formulation ...
... Liposomes have received attention not only for their utility as model membrane systems, but also for use in drug delivery. Typically, liposomes are used as drug carriers, with the solubilized drug encapsulated in the internal aqueous space formed by the liposomal lamellae. Liposomal drug formulation ...
Meclofenamic acid selectively inhibits FTO demethylation of m A
... make FTO an increasingly interesting target with respect to its functional links to human diseases. Another member of the AlkB family, ALKBH5, was also identified as an m6 A demethylase of mRNA using Fe2+ and cofactor 2OG, which together function to oxidatively remove the methyl group in m6 A-contai ...
... make FTO an increasingly interesting target with respect to its functional links to human diseases. Another member of the AlkB family, ALKBH5, was also identified as an m6 A demethylase of mRNA using Fe2+ and cofactor 2OG, which together function to oxidatively remove the methyl group in m6 A-contai ...
The Cultural, Spiritual and Ethical Aspects of Xenotransplantation
... a person who has died as a result of brain damage, for example through a stroke or accident, but it may also be a living donor who has donated, for example, a kidney or some bone marrow. This type of transplant, where the donor and the recipient are both of the same species (in this case human), is ...
... a person who has died as a result of brain damage, for example through a stroke or accident, but it may also be a living donor who has donated, for example, a kidney or some bone marrow. This type of transplant, where the donor and the recipient are both of the same species (in this case human), is ...