By I\ 0. BOWER, M.A., Camb., Assistant to the Professor of Botany in
... how in the lower portions of the main root the two originally separate protoxylem masses unite centrally to form a single xylem plate, but that for some distance below the point of transition from root to stem this coalescence does not take place, the centre of the root being occupied by a mass of p ...
... how in the lower portions of the main root the two originally separate protoxylem masses unite centrally to form a single xylem plate, but that for some distance below the point of transition from root to stem this coalescence does not take place, the centre of the root being occupied by a mass of p ...
Renal tubular Sirt1 attenuates diabetic albuminuria by
... We further investigated the effects of Sirt1 overexpression in PT in another diabetic model and 5/6 nephrectomized (5/6Nx) mice. We crossed our Sirt1 TG mice with obese db/db mice and produced Sirt1 TG-db/db mice (TG-db/db). Plasma glucose concentrations and body weights were significantly greater i ...
... We further investigated the effects of Sirt1 overexpression in PT in another diabetic model and 5/6 nephrectomized (5/6Nx) mice. We crossed our Sirt1 TG mice with obese db/db mice and produced Sirt1 TG-db/db mice (TG-db/db). Plasma glucose concentrations and body weights were significantly greater i ...
The yolk syncytial layer regulates myocardial
... heart malformations and subsequently determined that the 124H4 clone is identical to the previously reported transcription factor gene mtx1 (Hirata et al., 2000). mtx1 is a Mix-type homeobox gene that is expressed exclusively in the YSL from the oblong stage (3.7 hpf) until 80% epiboly (8.3 hpf) (Hi ...
... heart malformations and subsequently determined that the 124H4 clone is identical to the previously reported transcription factor gene mtx1 (Hirata et al., 2000). mtx1 is a Mix-type homeobox gene that is expressed exclusively in the YSL from the oblong stage (3.7 hpf) until 80% epiboly (8.3 hpf) (Hi ...
EC 3.4.22.32 - Bio
... of signaling by extracellular regulated kinase (ERK)-2 and p21ras. It is speculated that the possible protective effect of bromelain in murine EAE (experimental allergic encephalomyelitis), the animal model of multiple sclerosis, is due to proteolytic cleavage of accessory molecules involved in the ...
... of signaling by extracellular regulated kinase (ERK)-2 and p21ras. It is speculated that the possible protective effect of bromelain in murine EAE (experimental allergic encephalomyelitis), the animal model of multiple sclerosis, is due to proteolytic cleavage of accessory molecules involved in the ...
Nkx2-5 mutation causes anatomic hypoplasia of the cardiac
... washed, and imaged by standard methods using 32P-labeled probes for Nkx2-5 or GAPDH. β-Gal staining and assay. Hearts that expressed minK-lacZ were stained with X-gal for examination of the conduction system as previously described (13). Microscopic sections were obtained from stained hearts embedde ...
... washed, and imaged by standard methods using 32P-labeled probes for Nkx2-5 or GAPDH. β-Gal staining and assay. Hearts that expressed minK-lacZ were stained with X-gal for examination of the conduction system as previously described (13). Microscopic sections were obtained from stained hearts embedde ...
... conditions, the contribution of these cells to the inflammatory reaction may be moderate. However, under conditions of bone marrow impairment, local proliferation may be intensified replacing systemic reactions to a certain degree, a mechanism which has been shown to occur similarly in the liver of ...
Lipoprotein Lipase in the Arterial Wall
... The initial step in the development of atherosclerotic lesions is suggested to be the retention of LDL.13–15 Kinetic studies have provided evidence for sequestration of LDL in the normal arterial wall in a pool that exchanges slowly with plasma LDL. In atherosclerosis-prone areas, ie, in branch poin ...
... The initial step in the development of atherosclerotic lesions is suggested to be the retention of LDL.13–15 Kinetic studies have provided evidence for sequestration of LDL in the normal arterial wall in a pool that exchanges slowly with plasma LDL. In atherosclerosis-prone areas, ie, in branch poin ...
Negative regulators of integrin activity - Journal of Cell Science
... leucocytes, there is compelling evidence that a clasp formed by a salt-bridge between the a- and b-tails is crucial for maintaining these receptors in their inactive conformation (Springer and Dustin, 2012; Ye et al., 2012). For the b1 integrins, which predominantly facilitate matrix binding of adhe ...
... leucocytes, there is compelling evidence that a clasp formed by a salt-bridge between the a- and b-tails is crucial for maintaining these receptors in their inactive conformation (Springer and Dustin, 2012; Ye et al., 2012). For the b1 integrins, which predominantly facilitate matrix binding of adhe ...
Expression, purification and characterization of azurin derived
... Azurin is a low molecular weight protein member of the cupredoxin family and produced by Pseudomonas aeruginosa. Several studies (Chaudhari et al., 2006; Chaudhari et al., 2007; Yamada et al., 2002b) demonstrated that azurin has anticancer, antiparasitic and antiviral activity and that azurin behave ...
... Azurin is a low molecular weight protein member of the cupredoxin family and produced by Pseudomonas aeruginosa. Several studies (Chaudhari et al., 2006; Chaudhari et al., 2007; Yamada et al., 2002b) demonstrated that azurin has anticancer, antiparasitic and antiviral activity and that azurin behave ...
Induction and Fixation of Polarity -Early Steps in Plant Morphogenesis
... polarity is aligned correctly (39). This phenomenon resembles the situation in Hydra and is consistent with the idea of an all-or-none polarity. Irradiation with strong polarized light can cause doubling of the rhizoid pole (53),which suggests that polarity is induced de novo and is not inherited. T ...
... polarity is aligned correctly (39). This phenomenon resembles the situation in Hydra and is consistent with the idea of an all-or-none polarity. Irradiation with strong polarized light can cause doubling of the rhizoid pole (53),which suggests that polarity is induced de novo and is not inherited. T ...
Presynaptic Inhibition by GABA Is Mediated via Two Distinct GABA
... Cl conductance in bipolar-cell synaptic terminals was activated by muscimol (Fig. 2A), and 50-200 FM picrotoxin was able to abolish the conductance change produced by l-5 FM GABA (Fig. 4A). As shown in Figure 4B, however, bicuculline had little effect. This was true of bicuculline itself and of the ...
... Cl conductance in bipolar-cell synaptic terminals was activated by muscimol (Fig. 2A), and 50-200 FM picrotoxin was able to abolish the conductance change produced by l-5 FM GABA (Fig. 4A). As shown in Figure 4B, however, bicuculline had little effect. This was true of bicuculline itself and of the ...
Lateral root initiation is a probabilistic event whose frequency is set
... that are treated with auxin or that overproduce it form more LRs, while plants that are impaired in auxin signalling form fewer (for a review, see Fukaki et al., 2007). The role of auxin, however, is not simple. Auxin is involved in ...
... that are treated with auxin or that overproduce it form more LRs, while plants that are impaired in auxin signalling form fewer (for a review, see Fukaki et al., 2007). The role of auxin, however, is not simple. Auxin is involved in ...
Downloaded - The Journal of Cell Biology
... The Rockefeller University Press, 0021-9525/2003/03/433/17 $8.00 The Journal of Cell Biology, Volume 160, Number 3, February 3, 2003 433–449 http://www.jcb.org/cgi/doi/10.1083/jcb.200211083 ...
... The Rockefeller University Press, 0021-9525/2003/03/433/17 $8.00 The Journal of Cell Biology, Volume 160, Number 3, February 3, 2003 433–449 http://www.jcb.org/cgi/doi/10.1083/jcb.200211083 ...
Myosin V Plays an Essential Role in the Thyroid Hormone
... microfilaments and activates actin-based endocytosis of D2containing vesicles, leading to a rapid fall in D2 levels in the cell activity (5, 8, 9). Importantly, repolymerization of the microfilaments in the absence of thyroid hormone does not alter D2 turnover or activate the actin-based endocytosis ...
... microfilaments and activates actin-based endocytosis of D2containing vesicles, leading to a rapid fall in D2 levels in the cell activity (5, 8, 9). Importantly, repolymerization of the microfilaments in the absence of thyroid hormone does not alter D2 turnover or activate the actin-based endocytosis ...
history and scope of microbiology
... Pathogen must be isolated and grown in lab in pure culture Pathogen from pure cultures must cause disease when inoculated into healthy, susceptible lab animal Same pathogen must be isolated from the diseased lab animal ...
... Pathogen must be isolated and grown in lab in pure culture Pathogen from pure cultures must cause disease when inoculated into healthy, susceptible lab animal Same pathogen must be isolated from the diseased lab animal ...
Zinc transporters that regulate vacuolar zinc storage in
... Studies of the yeast Saccharomyces cerevisiae have led to rapid progress in understanding zinc homeostasis at the molecular level (Guerinot and Eide, 1999). Zinc uptake in S.cerevisiae is mediated primarily by two different systems in the plasma membrane: a high af®nity system encoded by ZRT1 (Zhao ...
... Studies of the yeast Saccharomyces cerevisiae have led to rapid progress in understanding zinc homeostasis at the molecular level (Guerinot and Eide, 1999). Zinc uptake in S.cerevisiae is mediated primarily by two different systems in the plasma membrane: a high af®nity system encoded by ZRT1 (Zhao ...
Receptors Distinct Parasite Molecules and Host Chemoattractant
... that trigger MyD88-dependent signaling cascades. Moreover, our data reveal a hitherto unknown underlying complexity to MyD88dependent signaling, in that multiple pathways leading to distinct outcomes can be triggered dependent upon upstream receptor-ligand interactions. ...
... that trigger MyD88-dependent signaling cascades. Moreover, our data reveal a hitherto unknown underlying complexity to MyD88dependent signaling, in that multiple pathways leading to distinct outcomes can be triggered dependent upon upstream receptor-ligand interactions. ...
Peer-Review Draft: Report on Carcinogens Monograph on
... for a disease to occur describes a complete causal effect. However, this is not a practical definition for infectious diseases that emerge from complex interactions of multiple factors and may be caused by more than a single agent. An important consideration regarding multicausality is that most of ...
... for a disease to occur describes a complete causal effect. However, this is not a practical definition for infectious diseases that emerge from complex interactions of multiple factors and may be caused by more than a single agent. An important consideration regarding multicausality is that most of ...
... RNS production correlates well with histopathological mucosal damage and with bacterial load[14,15]. The permanent recruitment of inflammatory cells to infectious foci results in progressive tissue damage. Asymptomatic H. pylori-infected individuals likely develop very weak gastric inflammation in r ...
Chapter 1: Overview - Worcester Polytechnic Institute
... admirable, and I thank you for that. I wish there were words to express my gratitude for supporting and guiding me throughout these past four years. I only hope that I have reached all your expectations and if not, you have me for the next ten years. These past few years you became more than an advi ...
... admirable, and I thank you for that. I wish there were words to express my gratitude for supporting and guiding me throughout these past four years. I only hope that I have reached all your expectations and if not, you have me for the next ten years. These past few years you became more than an advi ...
- Wiley Online Library
... humans upon ingestion of contaminated food. Listeriosis involves self-limiting gastrointestinal symptoms in otherwise healthy individuals but can also develop into more systemic conditions, primarily affecting the brain as well as the fetus in pregnant women (Allerberger and Wagner, 2010). In such s ...
... humans upon ingestion of contaminated food. Listeriosis involves self-limiting gastrointestinal symptoms in otherwise healthy individuals but can also develop into more systemic conditions, primarily affecting the brain as well as the fetus in pregnant women (Allerberger and Wagner, 2010). In such s ...