DORNRÖSCHEN is a direct target of the auxin response factor
... event between the linked mp and drn loci, and progeny of the resulting mpS319/+, drn/drn lines were subjected to detailed phenotypic and genetic analyses in the F3 generation. The primers used for genotyping are included in Table 1. Paired Student’s t-tests were performed on select phenotypic data t ...
... event between the linked mp and drn loci, and progeny of the resulting mpS319/+, drn/drn lines were subjected to detailed phenotypic and genetic analyses in the F3 generation. The primers used for genotyping are included in Table 1. Paired Student’s t-tests were performed on select phenotypic data t ...
Posttranslational Modification of MDM2
... the amino terminal 115 residues (which, incidentally, contain only one SQ motif, located at position 17; 35, 36). Interestingly, however, although physiological phosphorylation of ser-17 has yet to be confirmed, the phosphorylation site itself has been reported to have a significant impact on the ab ...
... the amino terminal 115 residues (which, incidentally, contain only one SQ motif, located at position 17; 35, 36). Interestingly, however, although physiological phosphorylation of ser-17 has yet to be confirmed, the phosphorylation site itself has been reported to have a significant impact on the ab ...
E7.5 endoderm induction by adjacent germ layers
... stomach, pancreas and duodenum (Fig. 1A,B; regions I and III). In situ expression of Pdx1 in E9.5 embryos containing a lac Z reporter integrated into a Pdx1 allele verifies that Pdx1 expression (in blue) is restricted to pancreatic regions I and III (Fig. 1A, E9.5). NeuroD and SS are also expressed ...
... stomach, pancreas and duodenum (Fig. 1A,B; regions I and III). In situ expression of Pdx1 in E9.5 embryos containing a lac Z reporter integrated into a Pdx1 allele verifies that Pdx1 expression (in blue) is restricted to pancreatic regions I and III (Fig. 1A, E9.5). NeuroD and SS are also expressed ...
Calcium and Plant Development - Labs
... of plants as we realize the importance of calcium ions (Ca2+) in mediating many different processes. The function of Ca2+ as a "second messenger" in ...
... of plants as we realize the importance of calcium ions (Ca2+) in mediating many different processes. The function of Ca2+ as a "second messenger" in ...
Reabsorption of the Nephrotoxin Ochratoxin A Along the Rat
... proportional to the concentration of OTA. Thus, the FR determined during infusion with 1026 mol/liter is the same as for lower concentrations that occur during natural exposure (Kuiper-Goodman and Scott, 1989). Furthermore, manipulation of OTA reabsorption (as discussed below) should be a tool to in ...
... proportional to the concentration of OTA. Thus, the FR determined during infusion with 1026 mol/liter is the same as for lower concentrations that occur during natural exposure (Kuiper-Goodman and Scott, 1989). Furthermore, manipulation of OTA reabsorption (as discussed below) should be a tool to in ...
Microtubule Reconfiguration during Axonal Retraction Induced by
... remnant (white arrowheads), and sinusoidal bends along the axonal shaft (black arrowheads). D, The percentages of different axonal behaviors after NOC-7 treatment, compared with the percentages for control cultures (for more details, see Results). Scale bar, 20 m. ...
... remnant (white arrowheads), and sinusoidal bends along the axonal shaft (black arrowheads). D, The percentages of different axonal behaviors after NOC-7 treatment, compared with the percentages for control cultures (for more details, see Results). Scale bar, 20 m. ...
Auxin transport routes in plant development
... The plant hormone auxin (the predominant form of which is indole3-acetic acid; IAA) is a major coordinating signal in the regulation of plant development. Many aspects of auxin action depend on its differential distribution within plant tissues, where it forms local maxima or gradients between cells ...
... The plant hormone auxin (the predominant form of which is indole3-acetic acid; IAA) is a major coordinating signal in the regulation of plant development. Many aspects of auxin action depend on its differential distribution within plant tissues, where it forms local maxima or gradients between cells ...
Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA
... (Suzuki et al., 2000). This autoinhibited BAX monomer may be further stabilized by associated proteins (Reed, 2006). By contrast, the C-terminal a9 helix of BAK is constitutively inserted in the MOM, and its activity is inhibited by a mammalian restricted VDAC isoform, VDAC2, which occupies the dime ...
... (Suzuki et al., 2000). This autoinhibited BAX monomer may be further stabilized by associated proteins (Reed, 2006). By contrast, the C-terminal a9 helix of BAK is constitutively inserted in the MOM, and its activity is inhibited by a mammalian restricted VDAC isoform, VDAC2, which occupies the dime ...
SOX9 specifies the pyloric sphincter epithelium
... The function of SOX9 was recently shown to be dependent and regulated by its nuclear-cytoplasmic hindgut and in the midgut (Fig. 2A). At this stage, SOX9 translocation in the developing gonad (de Santa Barbara et al., expression in the esophageal epithelium is high at the base of 2000; Gasca et al., ...
... The function of SOX9 was recently shown to be dependent and regulated by its nuclear-cytoplasmic hindgut and in the midgut (Fig. 2A). At this stage, SOX9 translocation in the developing gonad (de Santa Barbara et al., expression in the esophageal epithelium is high at the base of 2000; Gasca et al., ...
Lysis-deficient phages as novel therapeutic agents for controlling
... determination in clinical situations. A phage that kills the target cell but is incapable of host cell lysis would alleviate these concerns without compromising efficacy. Results: We developed a recombinant lysis-deficient Staphylococcus aureus phage P954, in which the endolysin gene was rendered no ...
... determination in clinical situations. A phage that kills the target cell but is incapable of host cell lysis would alleviate these concerns without compromising efficacy. Results: We developed a recombinant lysis-deficient Staphylococcus aureus phage P954, in which the endolysin gene was rendered no ...
Collagen Diversity, Synthesis and Assembly
... IX, XI, XII and XIII), further diversity in the ␣ chains is introduced at the transcriptional level through the formation of alternatively spliced variants. Collagen VI molecules assemble into the so-called beaded filaments, with a periodicity of 110 nm (Fig. 2.3). Unlike fibrillar collagens, there ...
... IX, XI, XII and XIII), further diversity in the ␣ chains is introduced at the transcriptional level through the formation of alternatively spliced variants. Collagen VI molecules assemble into the so-called beaded filaments, with a periodicity of 110 nm (Fig. 2.3). Unlike fibrillar collagens, there ...
Stability of a promiscuous plasmid in different hosts: no
... time series data. First, a simple difference equation model was formulated that assumes that at any generation, the abundance of the plasmid-free cells (m) increases due to (1) plasmid loss of the wildtype cells (n) at a segregation frequency l, and (2) growth of segregants by a factor of 21+s, wher ...
... time series data. First, a simple difference equation model was formulated that assumes that at any generation, the abundance of the plasmid-free cells (m) increases due to (1) plasmid loss of the wildtype cells (n) at a segregation frequency l, and (2) growth of segregants by a factor of 21+s, wher ...
Functional analysis of parvin and different modes of IPP
... (CH) domains separated by a linker sequence, and a less-well conserved N-terminal region. In vivo structure–function analysis revealed that all the domains are essential for parvin function, whereas recruitment at integrin adhesion sites is mediated by two localization signals: one located within th ...
... (CH) domains separated by a linker sequence, and a less-well conserved N-terminal region. In vivo structure–function analysis revealed that all the domains are essential for parvin function, whereas recruitment at integrin adhesion sites is mediated by two localization signals: one located within th ...
OglIb~3 Integrin Dissociation Induced by EDTA Results in
... pentalaminar interplatelet structures. EDTA treatment is known to induce an irreversible loss of platelet aggregability which is due to irreversible dissociation of the membrane GPl/b-lIIa complexes. In the present study, we looked for involvement of GPIIb-IIIa in the formation of these pentalaminar ...
... pentalaminar interplatelet structures. EDTA treatment is known to induce an irreversible loss of platelet aggregability which is due to irreversible dissociation of the membrane GPl/b-lIIa complexes. In the present study, we looked for involvement of GPIIb-IIIa in the formation of these pentalaminar ...
2004__MORRIS_et_al_Transpor... - Institute of Experimental Botany
... Auxin exported by the apical tissues of intact dicotyledonous plants moves downwards through the stem and root by a mechanism that has all the characteristics of the slow, polar transport first described from coleoptile and stem segments (33, 59). In stems, this transport occurs basipetally, but not ...
... Auxin exported by the apical tissues of intact dicotyledonous plants moves downwards through the stem and root by a mechanism that has all the characteristics of the slow, polar transport first described from coleoptile and stem segments (33, 59). In stems, this transport occurs basipetally, but not ...
Pulmonary Surfactant Protein A Activates a
... Jason Lees,* Eric Tibesar,* and Larry S. Schlesinger2† Surfactant protein A (SP-A), a major component of lung surfactant, binds to macrophages and has been shown to alter several macrophage biological functions, including up-regulation of macrophage mannose receptor (MR) activity. In the present stu ...
... Jason Lees,* Eric Tibesar,* and Larry S. Schlesinger2† Surfactant protein A (SP-A), a major component of lung surfactant, binds to macrophages and has been shown to alter several macrophage biological functions, including up-regulation of macrophage mannose receptor (MR) activity. In the present stu ...
The scaffolding protein Cnk Interacts with Alk to Promote Visceral
... present affiliation: Department of Biology, Faculty of Science, University of Antwerp, Groenenborgerlaan 171, BE- ...
... present affiliation: Department of Biology, Faculty of Science, University of Antwerp, Groenenborgerlaan 171, BE- ...
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic
... remodeling of the Ca2+ signaling components [4]. The heart is a highly plastic organ that undergoes hypertrophy in response to different types of stimuli [5,6]. The remodeling responsible for cardiac hypertrophy is a compensatory mechanism that increases the stroke volume to meet the work demand of ...
... remodeling of the Ca2+ signaling components [4]. The heart is a highly plastic organ that undergoes hypertrophy in response to different types of stimuli [5,6]. The remodeling responsible for cardiac hypertrophy is a compensatory mechanism that increases the stroke volume to meet the work demand of ...
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... fusion between two separate cell populations whose mitochondrial matrix is labeled in a different manner (i.e., with green and red mitochondrial-targeted fluorescent proteins). The distinct mitochondrial labels in fused cells (polykarions) colocalize only when there are mitochondrial fusion events t ...
... fusion between two separate cell populations whose mitochondrial matrix is labeled in a different manner (i.e., with green and red mitochondrial-targeted fluorescent proteins). The distinct mitochondrial labels in fused cells (polykarions) colocalize only when there are mitochondrial fusion events t ...
Redefining the role of ectoderm in somitogenesis
... Fgf signalling (Diez del Corral et al., 2003) and somite anteriorposterior polarity is established (Saga and Takeda, 2001). Furthermore, the first signs of morphological somite formation occur as peripheral PSM cells undergo a mesenchymal-to-epithelial transition (Duband et al., 1987; Kulesa and Fra ...
... Fgf signalling (Diez del Corral et al., 2003) and somite anteriorposterior polarity is established (Saga and Takeda, 2001). Furthermore, the first signs of morphological somite formation occur as peripheral PSM cells undergo a mesenchymal-to-epithelial transition (Duband et al., 1987; Kulesa and Fra ...
The Histone Variant H2A.W Defines Heterochromatin and Promotes
... at heterochromatin marked by H3K9me2 (Loyola and Almouzni, 2007). Although H2A.Z and H3.3 are predominantly linked to transcriptional activation, they are also associated with heterochromatin maintenance. In yeast, H2A.Z is enriched in subtelomeric regions and prevents spreading of telomeric heteroc ...
... at heterochromatin marked by H3K9me2 (Loyola and Almouzni, 2007). Although H2A.Z and H3.3 are predominantly linked to transcriptional activation, they are also associated with heterochromatin maintenance. In yeast, H2A.Z is enriched in subtelomeric regions and prevents spreading of telomeric heteroc ...
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... specified early during animal embryogenesis. In vertebrates, this process of axes formation is initiated by bcatenin, a transcriptional effector of Wnt signaling, which marks the prospective dorsal side. Thus far, all known regulators of axis specification that affect b-catenin include components of ...
... specified early during animal embryogenesis. In vertebrates, this process of axes formation is initiated by bcatenin, a transcriptional effector of Wnt signaling, which marks the prospective dorsal side. Thus far, all known regulators of axis specification that affect b-catenin include components of ...
The Neuronal Endomembrane System
... was circular in a manner analogous to chromosomal variations seen in highly mitotic tissues. For the sake of discussion, five distinctly different form categories were established. Some forms contained structures that are described herein for the first time. Most notable among these is the cis tubul ...
... was circular in a manner analogous to chromosomal variations seen in highly mitotic tissues. For the sake of discussion, five distinctly different form categories were established. Some forms contained structures that are described herein for the first time. Most notable among these is the cis tubul ...