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Leukocyte lipid bodies — Biogenesis and functions in inflammation
Leukocyte lipid bodies — Biogenesis and functions in inflammation

... [21,22], and TIP 47 (tail-interacting protein of 47 kDa) [23]. These proteins have been implicated in lipid body assembly and biogenesis [21,22,24,25]. By using techniques of protein identification in subcellular lipid body-enriched fractionation combined with immunodetection of proteins by EM or li ...
Decision making by p53: life, death and cancer
Decision making by p53: life, death and cancer

... phosphorylation of p53 on serine 46 will bias the transcriptional repertoire of p53 towards proapoptotic genes, thereby favoring death. An additional twist is introduced by the finding that PPM1D/Wip1, a phosphatase that inhibits serine 46 phosphorylation, is a positive transcriptional target of p53 ...
Retention in the Golgi apparatus and expression on the cell surface
Retention in the Golgi apparatus and expression on the cell surface

Universitat Autònoma de Barcelona
Universitat Autònoma de Barcelona

... Microbial Cell Factories, May 2012;11(1):55 2. Aggregation of the neuroblastoma-associated mutant (S120G) of the human nucleoside diphosphate kinase-A/NM23-H1 into amyloid fibrils Georgescauld F, Sabaté R, Espargaró A, Ventura S, Chaignepain S, Lacombe ML, Lascu I Naunyn Schmiedeberg’s Archives of P ...
Sleep and Host Defenses: A Review
Sleep and Host Defenses: A Review

... transformed cell lines maintained continuously by in essential for the development of gut T lymphocytes in vitro passage, but the relevance of this type of assay the mouse (9). Development of intestinal T cells furto in vivo situations has also not been well established. ther depends on local produc ...
C/EBPα triggers proteasome‐dependent degradation of cdk4 during
C/EBPα triggers proteasome‐dependent degradation of cdk4 during

1-Michelle_Stone_thesis
1-Michelle_Stone_thesis

... daughter  Emma  for  all  the  joy  she  brings  to  my  life.   ...
Glycogen Synthase Sensitivity to Insulin and Glucose-6
Glycogen Synthase Sensitivity to Insulin and Glucose-6

... important for regulation of glycogen synthase (4). At the NH2terminus, both Ser-7 (site 2) and Ser-10 (site 2a) influence glycogen synthase activity (5,6). Insulin administration causes dephosphorylation of glycogen synthase and, consequently, activation of the enzyme. In one study, insulin treatmen ...
Biogenesis and multifaceted roles of outer membrane
Biogenesis and multifaceted roles of outer membrane

... found to release spherical membrane-bound vesicles which were produced by pinching off of the OM (Chatterjee & Das, 1967). It was also observed that the density of some granular material was higher near the site where the ‘pinching off’ event was taking place on the OM, and some granules were enteri ...
PDF
PDF

... and most of the mesothorax, are a classical system in which to study the allocation of different subsets of cells to diverse developmental fates, i.e. body wall (dorsal mesothorax) or appendage (wing). Although we still lack a comprehensive picture of the genetic processes governing the development ...
Linkage Novel Type of Antigen with an Isopeptide Peptide Splicing
Linkage Novel Type of Antigen with an Isopeptide Peptide Splicing

... The proteasome is able to create spliced Ags, in which two distant parts of a protein are excised and ligated together to form a novel peptide, for presentation by MHC class I molecules. These noncontiguous epitopes are generated via a transpeptidation reaction catalyzed by the proteasomal active si ...
PIN-Dependent Auxin Transport: Action, Regulation
PIN-Dependent Auxin Transport: Action, Regulation

... members of the family, and look at the family from an evolutionary perspective. Next, we cover the cell biological and molecular aspects of PIN function, in particular the establishment of their polar subcellular localization. Hormonal and environmental inputs into the regulation of PIN action are s ...
The Role of Auxin in Abscission of Organs and Tissues
The Role of Auxin in Abscission of Organs and Tissues

... Whitelaw, 2001). Two types of AZs have been reported, the primary and secondary AZ. Primary AZs differentiate early in development, simultaneously with the development of the lateral organ at a predefined position (Addicott, 1982; Osborne & Morgan, 1989; Taylor & Whitelaw, 2001). By contrast, second ...
Comparison of induction during development between Xenopus
Comparison of induction during development between Xenopus

... of chd at 10 ng/ml of activin in Xenopus tropicalis was higher than that observed in Xenopus laevis , although the dose of activin that induces the genes expression is the same. In particular, the expression of chd was 5 times higher at 10 ng/ml of activin in Xenopus tropicalis than at the same dose ...
Maternal mRNAs are regulated by diverse P body
Maternal mRNAs are regulated by diverse P body

... particles in the cytoplasm of developing oocytes (Fig. 2 B). In arrested fog-2(q71) oocytes, the developmental expression pattern was not altered, but PUF-5 became tightly localized to large cytoplasmic foci (Fig. 2 C). Wild-type hermaphrodites depleted of sperm formed similar large particles, where ...
Identification of core functional region of murine IL-4 using
Identification of core functional region of murine IL-4 using

... had different sequences, all of them were able to bind to 11B.11 as determined by ELISA. It is reasonable to assume that the positive clones have peptide sequences similar to the epitopes of IL-4. In this case, they could effectively compete with IL-4 for binding to 11B.11 mAb. To address this quest ...
lysis strategy of streptococcus pneumoniae bacteriophages
lysis strategy of streptococcus pneumoniae bacteriophages

... detected. The overwhelming majority of phages of other bacterial species are absolutely incapable of bacterial lysis, trapping the phage progeny within the host cell, when the genes encoding lysins are deleted. Moreover, those rare mutants that bring about lysis depend only on phage-encoded factors. ...


... fluorescent protein) construct were obtained. FHT temporal and spatial profiles in normal and mechanically injured tissues are reported. The results show that FHT is specifically expressed in cells undergoing suberization and that it is induced by wounding and regulated by ABA and salicylic acid (SA ...
ภาพนิ่ง 1
ภาพนิ่ง 1

... vp) that are blocked at other steps in the carotenoid pathway also have reduced levels of ABA and exhibit ...
Phloem transport: a review of mechanisms and
Phloem transport: a review of mechanisms and

... this widely accepted Münch theory has required remarkably few adaptations, but the debate on alternative and additional hypotheses is still ongoing. Recently, a possible shortcoming of the Münch theory has been pointed out, suggesting that the Münch pressure flow is more suitable for herbs than for ...
Phloem transport: A review of mechanisms and controls (PDF
Phloem transport: A review of mechanisms and controls (PDF

... this widely accepted Münch theory has required remarkably few adaptations, but the debate on alternative and additional hypotheses is still ongoing. Recently, a possible shortcoming of the Münch theory has been pointed out, suggesting that the Münch pressure flow is more suitable for herbs than for ...
Serine Residues 286, 288, and 293 within the CIITA: A
Serine Residues 286, 288, and 293 within the CIITA: A

... initiating immune responses by activating the expression of the MHC class II genes and associated molecules (1– 6). MHC class II proteins facilitate the presentation of exogenously derived antigenic peptides on the surface of APCs, leading to recognition by CD4⫹ T cells and subsequent activation of ...
Formation of a highly peptide-receptive state of class II MHC.
Formation of a highly peptide-receptive state of class II MHC.

... This tyrosine is the most important MHC contact of the HA peptide (Stern et al., 1994). Discussion In this report we deduce the existence of two isomers of empty class II MHC that have very different peptide binding capacities. One isomer (active) binds peptide rapidly at endosomal pH (kon ≈ 105 M21 ...
Mechanisms of Early Microbial Establishment on Growing Root
Mechanisms of Early Microbial Establishment on Growing Root

... attaching on a root surface proliferate rapidly and form microcolonies and biofilms. Here, identical strains of Pseudomonas fluorescens expressing different fluorescent proteins are grown on tomato (Solanum lycopersicum L. ) plants. After 5 d of growth, microcolonies of identical colors are formed, ...
special paper calcium function and distribution during fertilization in
special paper calcium function and distribution during fertilization in

... styles of tobacco, pollen tube growth also required supplemental calcium in the medium (Tian and Russell, 1997b). When the external calcium concentration exceeds 5 3 106 M, actin filaments in the pollen tube of Lilium longiflorum become fragmented and cytoplasmic streaming stops (Kohno and Shimmen, ...
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Amitosis

Amitosis (a- + mitosis) is absence of mitosis, the usual form of cell division in the cells of eukaryotes. There are several senses in which eukaryotic cells can be amitotic. One refers to capability for non-mitotic division and the other refers to lack of capability for division. In one sense of the word, which is now mostly obsolete, amitosis is cell division in eukaryotic cells that happens without the usual features of mitosis as seen on microscopy, namely, without nuclear envelope breakdown and without formation of mitotic spindle and condensed chromosomes as far as microscopy can detect. However, most examples of cell division formerly thought to belong to this supposedly ""non-mitotic"" class, such as the division of unicellular eukaryotes, are today recognized as belonging to a class of mitosis called closed mitosis. A spectrum of mitotic activity can be categorized as open, semi-closed, and closed mitosis, depending on the fate of the nuclear envelope. An exception is the division of ciliate macronucleus, which is not mitotic, and the reference to this process as amitosis may be the only legitimate use of the ""non-mitotic division"" sense of the term today. In animals and plants which normally have open mitosis, the microscopic picture described in the 19th century as amitosis most likely corresponded to apoptosis, a process of programmed cell death associated with fragmentation of the nucleus and cytoplasm. Relatedly, even in the late 19th century cytologists mentioned that in larger life forms, amitosis is a ""forerunner of degeneration"".Another sense of amitotic refers to cells of certain tissues that are usually no longer capable of mitosis once the organism has matured into adulthood. In humans this is true of various muscle and nerve tissue types; if the existing ones are damaged, they cannot be replaced with new ones of equal capability. For example, cardiac muscle destroyed by heart attack and nerves destroyed by piercing trauma usually cannot regenerate. In contrast, skin cells are capable of mitosis throughout adulthood; old skin cells that die and slough off are replaced with new ones. Human liver tissue also has a sort of dormant regenerative ability; it is usually not needed or expressed but can be elicited if needed.
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