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Nature Rev.Genet. 8
Nature Rev.Genet. 8

... The AS-ICR is nonfunctional in males allowing the PWS-ICR to activate nearby genes The PWS-ICR promotes expression of an antisense Ube3a transcript in males ...
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... distince 5’ and 3’ ends, based on the deoxyribose sugar base-pairing (G to C and A to T) holds two strands together in an antiparallel arrangement ...
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... correspond to the nitrogenous base sequence of mRNA. ...
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DNA PPT - McKinney ISD Staff Sites
DNA PPT - McKinney ISD Staff Sites

... Cytosine ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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