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Cell Cycle
Cell Cycle

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Figure 9.8
Figure 9.8

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BIOCHEMISTRY 4.1 HOMEWORK

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Biology 303 EXAM II 3/14/00 NAME

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CB Mini-Practice Test for Unit 2
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... 12) When does DNA replicate? 13) Why is DNA replication described as semi conservative? Be able to list the base sequence of a strand of DNA when given a sequence from the opposite DNA strand. 15) List and describe the function of the 2 enzymes used in DNA replication we discussed in class. ...
ppt link
ppt link

... In circular chromosomes, such as E. coli, there is only one origin of replication. In circular chromosomes, unwinding and replication causes supercoiling, which may impede replication Topoisomerase – enzyme that relaxes supercoils by nicking strands ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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