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Glycolysis and Gluconeogenesis
Glycolysis and Gluconeogenesis

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... XI. Ask yourself “What If Questions”; e.g., Why does an individual with prolonged excess calorie intake but low cholesterol intake have high cholesterol levels? Background Fatty acid biosynthesis occurs when the body is energy rich. Postprandial, ATP is generated by glycolysis and the final common ...
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Carnitine-acylcarnitine translocase deficiency: metabolic

... Glucose is the major source of energy for the fetus [1]. Immediately after birth free fatty acids are mobilized from adipose tissue stores. A rapid increase in the activity of carnitine palmitoyltransferase I and II and a rise in the capacity to oxidize fatty acids is found in liver [2] and in heart ...
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Glyceroneogenesis



Glyceroneogenesis is a metabolic pathway which synthesizes glycerol 3-phosphate or triglyceride from precursors other than glucose. Usually glycerol 3-phosphate is generated from glucose by glycolysis, but when glucose concentration drops in the cytosol, it is generated by another pathway called glyceroneogenesis. Glyceroneogenesis uses pyruvate, alanine, glutamine or any substances from the TCA cycle as precursors for glycerol 3-phophate. Phosphoenolpyruvate carboxykinase (PEPC-K), which is an enzyme that catalyses the decarboxylation of oxaloacetate to phosphoenolpyruvate is the main regulator for this pathway. Glyceroneogenesis can be observed in adipose tissue and also liver. It is a significant biochemical pathway which regulates cytosolic lipid levels. Intense suppression of glyceroneogenesis may lead to metabolic disorder such as type 2 diabetes.
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