
Glycolysis and Gluconeogenesis
... hypoxia-inducible transcription factor stimulates synthesis of many glycolytic enzymes and GLUT-1 and 3 also stimulates vascular endothelial growth factor ...
... hypoxia-inducible transcription factor stimulates synthesis of many glycolytic enzymes and GLUT-1 and 3 also stimulates vascular endothelial growth factor ...
Urea cycle
... The activity of urea cycle is regulated at two levels: • Dietary intake is primarily proteins much urea (amino acids are used for fuel) • Prolonged starvation breaks down of muscle proteins much urea also • The rate of synthesis of four urea cycle enzymes and carbamoyl phosphate synthetase I ( ...
... The activity of urea cycle is regulated at two levels: • Dietary intake is primarily proteins much urea (amino acids are used for fuel) • Prolonged starvation breaks down of muscle proteins much urea also • The rate of synthesis of four urea cycle enzymes and carbamoyl phosphate synthetase I ( ...
Chapter 8
... • During each turn of the cycle, three carbon atoms enter (as pyruvate) and three leave as three carbon dioxide molecules ...
... • During each turn of the cycle, three carbon atoms enter (as pyruvate) and three leave as three carbon dioxide molecules ...
Relationship between Human Adipose Tissue Agouti and - Zen-Bio
... The human homologue of agouti, unlike its murine counterpart, is expressed in adipose tissue (Kwon et al. 1994), indicating a possible physiologic role for agouti in human adipose tissue. We showed previously that the FAS mRNA level is significantly higher in adipose tissue from obese Avy mice than ...
... The human homologue of agouti, unlike its murine counterpart, is expressed in adipose tissue (Kwon et al. 1994), indicating a possible physiologic role for agouti in human adipose tissue. We showed previously that the FAS mRNA level is significantly higher in adipose tissue from obese Avy mice than ...
Lipid Biosynthesis
... XI. Ask yourself “What If Questions”; e.g., Why does an individual with prolonged excess calorie intake but low cholesterol intake have high cholesterol levels? Background Fatty acid biosynthesis occurs when the body is energy rich. Postprandial, ATP is generated by glycolysis and the final common ...
... XI. Ask yourself “What If Questions”; e.g., Why does an individual with prolonged excess calorie intake but low cholesterol intake have high cholesterol levels? Background Fatty acid biosynthesis occurs when the body is energy rich. Postprandial, ATP is generated by glycolysis and the final common ...
Answer Set 2
... b. 5 mCi/mmol. The specific activity is halved because the number of moles of product (pyruvate) is twice that of the labeled substrate (glucose). GG18-3. Increased [ATP], [citrate], or [glucose-6-phosphate] inhibits glycolysis. Increased [AMP], [fructose-1,6-bisphosphate], and [fructose-2,6-bisphos ...
... b. 5 mCi/mmol. The specific activity is halved because the number of moles of product (pyruvate) is twice that of the labeled substrate (glucose). GG18-3. Increased [ATP], [citrate], or [glucose-6-phosphate] inhibits glycolysis. Increased [AMP], [fructose-1,6-bisphosphate], and [fructose-2,6-bisphos ...
Functional foods against metabolic syndrome
... Cocoa powder supplementation reduced body weight gain, obesity-related inflammation, insulin resistance, fatty liver disease and down-regulated the pro-inflammatory gene expression in the white adipose tissues (WAT) of high-fat diet mice (Gu, Yu, & Lambert, 2013). Cocoa extract reduced postprandial ...
... Cocoa powder supplementation reduced body weight gain, obesity-related inflammation, insulin resistance, fatty liver disease and down-regulated the pro-inflammatory gene expression in the white adipose tissues (WAT) of high-fat diet mice (Gu, Yu, & Lambert, 2013). Cocoa extract reduced postprandial ...
PHARMACOLOGY (and other important compounds) Hey, Here is a
... - in the subendothelial cell matrix, exposed when injured - platelets have receptor that binds collagen -aggregation around exposed collagen - collagen is highly thrombogenic ...
... - in the subendothelial cell matrix, exposed when injured - platelets have receptor that binds collagen -aggregation around exposed collagen - collagen is highly thrombogenic ...
CH 2
... double bond and two hydroxyl groups) intermediate, as the enzyme takes advantage of the dissociability of the hydrogen on the terminal hydroxyl group to generate an oxyanion and move the C=O double bond to the terminal carbon, producing the aldehyde and reducing the ketone to an alcohol. ...
... double bond and two hydroxyl groups) intermediate, as the enzyme takes advantage of the dissociability of the hydrogen on the terminal hydroxyl group to generate an oxyanion and move the C=O double bond to the terminal carbon, producing the aldehyde and reducing the ketone to an alcohol. ...
Chapter 17 - FIU Faculty Websites
... enhancing aerobic glycolysis. Mutations in isocitrate dehydrogenase result in the synthesis of 2-hydroxyglutarate, which modifies methylation patterns in DNA. This modification alters gene expression and promotes rapid cell growth. ...
... enhancing aerobic glycolysis. Mutations in isocitrate dehydrogenase result in the synthesis of 2-hydroxyglutarate, which modifies methylation patterns in DNA. This modification alters gene expression and promotes rapid cell growth. ...
Fatty acid synthesis
... • Reduced importance in humans • Critical diseases of this pathway has not been reported because of this. • Variation in its activity between individuals may have an effect on the nature and extent of obesity. • Inhibition of lipogenesis is the lesion in Type I diabetes mellitus ...
... • Reduced importance in humans • Critical diseases of this pathway has not been reported because of this. • Variation in its activity between individuals may have an effect on the nature and extent of obesity. • Inhibition of lipogenesis is the lesion in Type I diabetes mellitus ...
Special aspects of renal metabolism
... The extracellular concentration of free amino is significantly lower than inside the cells The concentration gradient is maintained through active transport (requires ATP) that moves amino acids into cells Seven different transport systems are known that have overlapping specificities for diff ...
... The extracellular concentration of free amino is significantly lower than inside the cells The concentration gradient is maintained through active transport (requires ATP) that moves amino acids into cells Seven different transport systems are known that have overlapping specificities for diff ...
connective tissue [ppt]
... • Tropocollagen is synthesized by fibroblasts and released into extracellular space where they get polymerized to form collagen fibrils • Collagen on boiling gives gelatin ...
... • Tropocollagen is synthesized by fibroblasts and released into extracellular space where they get polymerized to form collagen fibrils • Collagen on boiling gives gelatin ...
Lesson 12. Hormones
... Insulin is a polypeptide hormone synthesized in the pancreas by β-cells, which construct a single chain molecule called proinsulin. Enzymes excise a portion of the proinsulin molecule called the C peptide, producing the actual insulin molecule. When in demand, the β-cells will release insulin togeth ...
... Insulin is a polypeptide hormone synthesized in the pancreas by β-cells, which construct a single chain molecule called proinsulin. Enzymes excise a portion of the proinsulin molecule called the C peptide, producing the actual insulin molecule. When in demand, the β-cells will release insulin togeth ...
Chapter 7A- Cellular Respiration: Glycolysis - TJ
... chain, pyruvate, mitochondrion, citric acid cycle, glycolysis, cytoplasm, glucose, 2 NADH, 6 NADH, 2 FADH2, 2 ATP, 34 ATP, 38 ATP. ...
... chain, pyruvate, mitochondrion, citric acid cycle, glycolysis, cytoplasm, glucose, 2 NADH, 6 NADH, 2 FADH2, 2 ATP, 34 ATP, 38 ATP. ...
Διαφάνεια 1 - Provincia di Foggia
... All of these additives function by addition to the end of the resin after preparation, or by addition to the glue-mix before resin application ...
... All of these additives function by addition to the end of the resin after preparation, or by addition to the glue-mix before resin application ...
ASPECTS OF ANAEROBIC METABOLISM IN
... Anodonta. At the higher pH [PEP]0.5 of three tissues of Anodonta is still lower, by about 50~, than the active variant of Mytilus adductor muscle. The effect of decreasing pH is much less in Anodonta than in Mytilus. The same holds for the effect of alanine. These findings fit well into the spectrum ...
... Anodonta. At the higher pH [PEP]0.5 of three tissues of Anodonta is still lower, by about 50~, than the active variant of Mytilus adductor muscle. The effect of decreasing pH is much less in Anodonta than in Mytilus. The same holds for the effect of alanine. These findings fit well into the spectrum ...
Metabolomic Profiling Identifies Biomarkers Associated
... – For use in models with other metabolites and metabolic parameters for: l The prediction of type 2 diabetes l Monitoring interventions in diabetes and prediabetes ...
... – For use in models with other metabolites and metabolic parameters for: l The prediction of type 2 diabetes l Monitoring interventions in diabetes and prediabetes ...
Biosynthesis of Amino Acids
... acids from their diet. Humans can only synthesize about half of the twenty amino acids. • In general, the more complex amino acids are essential amino acids in humans as they require enzymes that have been lost from the human genome over evolutionary time. • Most animals are much more restricted in ...
... acids from their diet. Humans can only synthesize about half of the twenty amino acids. • In general, the more complex amino acids are essential amino acids in humans as they require enzymes that have been lost from the human genome over evolutionary time. • Most animals are much more restricted in ...
Biochemistry Key Answers
... functions and deficiency manifestations of Vitamin-B12. 2. Describe how cholesterol is synthesized in our body. What are the products formed from Cholesterol? Write Short notes on: 1. Active form of Vitamin D and its biochemical role. 2. Catabolism of Hemoglobin. 3. Protein energy malnutrition 4. Ke ...
... functions and deficiency manifestations of Vitamin-B12. 2. Describe how cholesterol is synthesized in our body. What are the products formed from Cholesterol? Write Short notes on: 1. Active form of Vitamin D and its biochemical role. 2. Catabolism of Hemoglobin. 3. Protein energy malnutrition 4. Ke ...
Intro to Metabolism II and Glycolysis
... i. Capable of phosphorylating ADP ATP XXIV. Transfer of the phosphoryl group from phosphoenolpyruvate to ADP [S24] a. Irreversible reaction b. Notice again the name of the enzyme is for that of the reverse reaction. c. Pyruvate is the end product of glycolysis. d. 2 more ATP produced, to bring the ...
... i. Capable of phosphorylating ADP ATP XXIV. Transfer of the phosphoryl group from phosphoenolpyruvate to ADP [S24] a. Irreversible reaction b. Notice again the name of the enzyme is for that of the reverse reaction. c. Pyruvate is the end product of glycolysis. d. 2 more ATP produced, to bring the ...
Carnitine-acylcarnitine translocase deficiency: metabolic
... Glucose is the major source of energy for the fetus [1]. Immediately after birth free fatty acids are mobilized from adipose tissue stores. A rapid increase in the activity of carnitine palmitoyltransferase I and II and a rise in the capacity to oxidize fatty acids is found in liver [2] and in heart ...
... Glucose is the major source of energy for the fetus [1]. Immediately after birth free fatty acids are mobilized from adipose tissue stores. A rapid increase in the activity of carnitine palmitoyltransferase I and II and a rise in the capacity to oxidize fatty acids is found in liver [2] and in heart ...
Glyceroneogenesis

Glyceroneogenesis is a metabolic pathway which synthesizes glycerol 3-phosphate or triglyceride from precursors other than glucose. Usually glycerol 3-phosphate is generated from glucose by glycolysis, but when glucose concentration drops in the cytosol, it is generated by another pathway called glyceroneogenesis. Glyceroneogenesis uses pyruvate, alanine, glutamine or any substances from the TCA cycle as precursors for glycerol 3-phophate. Phosphoenolpyruvate carboxykinase (PEPC-K), which is an enzyme that catalyses the decarboxylation of oxaloacetate to phosphoenolpyruvate is the main regulator for this pathway. Glyceroneogenesis can be observed in adipose tissue and also liver. It is a significant biochemical pathway which regulates cytosolic lipid levels. Intense suppression of glyceroneogenesis may lead to metabolic disorder such as type 2 diabetes.