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1 BIOLOGY Genetics Chp 11 (& some 14) REPRODUCTION: process of producing _________ 2 types 1) ASEXUAL--- production of ________ from only _____ parent--- Offspring will be ___________ ______________ to the parent Advantage: Disadvantage: types-- Binary fission--used in ____________ cells-- parent cell ______ into ____ cells Fragmentation---many small ______ of the adult form into ______ organisms (starfish, planarian) Budding----new individual _______ off the original organism (hydra, yeast) Parthenogenesis---female creates a viable ______ cell without being _________ (some reptiles) 2) SEXUAL--- production of ________ from the union of _____ parent cells ( ______) forms a ________ male= _______ Female=__ Germ cells---Somatic cells--Offspring contain the genetic material from _______ parents Advantage: Disadvantage: type--- Fertilization---Every organism has its own chromosome number--** the Chromosome number ________ ________ reflect____________ Human chromosome number is ______(Diploid______ ) Haploid (__)= ___ 2 Homologous Chromosomes---Karyotype: Autosomes: Sex Chromosomes: Genetic Variations Very important for a _______________ of individuals --- allows for ________ Made possible due to ___________ reproduction----due to ________ Main Items that contribute to this variation--1) CROSSING OVER---during ___________ when the _______are formed and the ______ is shared. Makes the Homologous chromosomes no longer ___ 2) Independent assortment---during ________ and ______ when the ________ and the ________ line-up and then separate---no _____________ each gamete receives 1 chromosome from each of the 23 pairs 2 23 possible combinations within each gamete = _________________ 3) Random Fertilization---- any ________ might be fertilized by any _____ possible outcomes 2 23 x 2 23 = __________________ 3 Genetics : the science of ____________ which studies the mechanisms by which ______ are passed from _________ to __________ Heredity : The ________ of genetic _______ from _________ to ___________ Trait: a genetically determined ______________ Gregor Mendel (1860’s) is considered the ____________ he was a __________ lived in Austria worked with _________studied their many traits-Pollination: Self-pollination cross-pollination— Hybrid: He learned that he could __________ the offspring by controlling which __________ fertilized the female plants PROBABILITY: the __________ that a __________ event will __________ Examples -Flip 1 coin =what’s the chance of landing on heads? Flip 2 coins--Chance they both land on heads? Roll a 3 on a die Roll 2 dice & both land on 3? 4 Roll an 11 on 2 dice ? Within a population--- if this information is given… 45/ 100 people have type O blood 40/100 people have type A blood 10/100 people have type B blood 5/ 100 people have type AB blood What’s the chance of a couple being AB & O blood types? What’s the chance of having the man be type A & the woman type A ? MENDEL’S PREDICTIONS FROM THE PEA PLANTS Monohybrid Cross--- (page 269) Generation: P generation: f1 generation (f= filial, latin son/daughter) Ratio that he found---- 5 Genetics governed by _____ Principles 1. Principle of ____________& ____________ Dominant trait: _______________________________________ Recessive trait :____________________________________ *The ____________trait will always _________(hide) the _________ *In order for the ____________trait to show through on the offspring _______ parents must ______it to their ____________ Each version of a gene is called an _________________ 2. Principle of _____________---1 ______(factor) must come from ____________ & the other from ___________ 3. Principle of ______________ _____________ Every __________(factor) is separate from the other ___ Gene:____________________________________________________ --Each gene controls a particular ___________ --Genes always appear in __________ ---Each member of the pair is called an ______________ Your genes determine what you look like on the outside & on the inside. PHENOTYPE :___________________________________________ GENOTYPE :_____________________________________________ When both _________are the ________ = ________________ When the ___________are __________ = _________________ 6 PREDICTING the results of a MONOHYBRID cross-- ___ Trait T = Tall which is ___________ t = Short which is __________ Predict the genotypic & phenotypic ratios for a TT x tt cross Genotypes Homozygous Dominant =____ Heterozygous = _____ Homozygous Recessive = ____ Ratio= ___ ___ ___ Phenotypes & ____ are BOTH Tall = ____ = Short _____ Ratio= INCOMPLETE DOMINANCE :__________________________________ CODOMINANCE:__________________________________________________ * there will be ____ Phenotypes Example --Red flowers=___- White=___ Pink= ____ Cross a Red flower with a pink flower Phenotypes Red=___ Pink=____ White=___ Genotypes RR=___ Rr=_____ rr=____ Polygenic character: _____________________________________________________ examples--- ________ color and ______ color and __________ 7 Predicting results of a dihybrid cross---_____ traits * 2 ways to do it---2 Punnett squares or 1 16 square Punnett square H = Hiker’s thumb A=attached ears Show cross between AAHH x AaHh Phenotypes--4 possible Attached Hikers=___ Unattached stub=___ Attached stub=____ unattached Hikers=____ Genotypes--9 possible AAHH AaHH aaHH AAHh AaHh aaHh AAhh Aahh aahh Multiple Alleles: ________________________________ Best example is blood types Blood type A = _____ or _____ Blood type B = ______ or _____ Blood type AB = ______ Blood type O = _________ Cross dad with type O with mom who is type A & her father is type O 8 Many Genetic studies done on ___________:___________ 1st to use was __________________ he discovered AUTOSOMES:_________________________ Sex Chromosomes:_______________________________ XX = ______ XY=______--only____can pass the Y SEX-LINKED traits:____________________________________ examples--color blindness, hemophiliacs -the trait is only carried on the ____ The Y does ____ - So the trait is passed to the _____by the ______ colorblindness-- _____% males <____females Cross a color-blind male with a carrier female **Results determined by question if how many kids than out of___ if out of males than out of ____ if out of females than out of ___ Hemophiliac---lack blood-clotting protein Males either have it ____ or they don’t _____ Females can have it _____, not have it_____ carry it____ What % of the kids in a marriage between a man whose mother didn’t have it but his maternal grandmother did with a woman who is a hemophiliac. Sex-influenced traits:_______________________________ Example:_______________---- Dominant in ________ --- Recessive in _______ bb--___________ BB-- _______________ Bb--__________________________ 9 Human genetic traits In humans there are ____chromosomes= __________genes there are problems in studying human genes 1. 2. 3. Some ways we study the human population for genetics are... 1. 2. 3. Genetic Diseases Huntington disease--_________trait --don’t know you have it until ________after ______ Today we have the ________________ so you can be tested when _________ & counseled if you want to have ________ Sickle –Cell anemia---- found mainly in __________ Errors in Chromosome Sorting--Nondisjunction conditions---___________________________ Polyploidy---one egg with ______ another egg with ______ this can cause an embryo ... ________ 1 too many ________ 1 too less ________ won’t develop If extra chromosome is in the _____ pair it is _____________ -If extra is in the 23rd pair --- _______ called ____________ If the 23rd pair is missing one ---______ called __________ 10 Ways we can study embyro before it is born.... 1. Karyotype-_______________________________ 2. Amniocentesis-_______________________________ 3.Fetoscopy-_______________________________ 4. Ultrasound-_______________________________ 5. Chorion villi sampling-___________________________