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Honors Biology Final Exam Review Sheet 1. Protein Synthesis base triplets/codons/anticodons: what are they?, what type of information do they represent?, to what molecules do these terms refer to? redundancy of the DNA code: what advantage does having multiple codons for a single amino acid give when a mutation occurs? amino acid sequence in determining protein type: why is it important? transcription and mRNA processing: what happens during transcription?, where does it occur?, what happens during mRNA processing? translation and protein synthesis: what happens during translation?, where does it occur? mutations and mutagens: definitions, types of mutations, examples of mutagens, effect on protein formed and overall effect on organism (relationship of genotype to phenotype or in other words the relationship of DNA→gene→protein→phenotype) effect of point mutations on DNA : why is the order of amino acids important in protein structure?, what can happen in point mutations top affect that order? 2. Mendelian genetics associated terms: be able to define genotype, phenotype, homozygous, heterozygous, alleles, etc. one trait crosses/ monohybrid crosses: be able to complete assorted problems, analyze Punnett square information incomplete dominance: what is it?, how would you recognize inheritance by incomplete dominance?, how would you set up a problem using Punnett squares? two trait crosses and dihybrid crosses: be able to solve these types of problems sex-linked traits and examples: be able to solve these types of problems, what makes them different from traits carried on autosomes?, what is different in the inheritance pattern of these traits? pedigree charts: be able to analyze Mendel’s rules: paraphrase the concepts of dominance, segregation and independent assortment Punnett squares: be able to set up and work through them, explain how these model events in meiosis multiple alleles: what does it mean when a trait is inherited by multiple alleles?, give an example. prenatal genetic testing methods: provide some examples and be able to evaluate them (what are the advantages and disadvantages of each?, what information do these tests provide? karyotyping: what is it?, what information does it provide?, be able to analyze a karyotype chromosomal abnormalities (your projects): be able to recognize a karyotype for each of these: Klinefelter’s Syndrome, Turner’s Syndrome, Down Syndrome, what event causes each of these? 3. Mitosis/Meiosis stages in each/major events in these stages: go back to the animations online for these---review as many times as needed for understanding of these processes! homologous chromosomes: what are they? What happens to them in mitosis? in meiosis? outcome in terms of chromosome number and genetics of new daughter cells: do the chromosome numbers remain the same or do they change?, if they change-how do they change?, are the daughter cells the same as each other and than parent cell or are they different from each other and the parent cell? method of reproduction associated with each: when is mitosis used? meiosis? unique events associated with meiosis: what sets meiosis apart from mitosis? 4. Biotechnology DNA fingerprinting: how is it done?, be able to analyze DNA fingerprints, what information can it and can’t it tell you? PCR: what is it?, when might it be needed? gel electrophoresis: what is it?, how are the fragments separated? terms: restriction enzymes, plasmids, transgenic, clone, GMO gene therapy: how is it accomplished? creating a recombinant plasmid: how is this done? 5. Evolution by Means of Natural Selection definition of evolution: why is it important to understand this process?, how do we use this understanding today? indirect and direct evidence of evolution: how do we know evolution has occurred?, process of natural selection: how does it work?, what are some misconceptions of natural selection? factors contributing to speciation: how are new species formed?, how do we know when a new species is formed? Hardy-Weinberg principle and associated equations (bring calculator): what does hardy-Weinberg tell us?, what are the equations?, be able to work through the equations.