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Transcript
Biology 260 – Fall 2013
North Seattle Community College
GROUP QUIZ 06-07
NAME: __KEY answers are in blue______
(
/34 pts)
1. The general characteristics unique to eukaryotic cells include (1 pt)
A. a cell wall
B. a nucleus enclosed in a membrane
C. other organelles
D. other membrane bound organelles
E. a, b, and c
F. a, b, and d
G. b and d
2. Select the statement that is FALSE (1 pt)
A. Cilia are found on eukaryotic cells and beat in synchrony to help flush microbes out of the body.
They are not found on prokaryotic cells.
B. 80S ribosomes are found in the cytoplasm of eukaryotic cells, 70S ribosomes are found in prokaryotic
cells and in eukaryotic mitochondria.
C. Lysosomes contain anabolic enzymes that help build macromolecules.
D. The plasma membrane has many proteins embedded within it that act as transport proteins, receptor
proteins that sense the environment, and structural proteins.
3. Match the appropriate term with its definition (4 pts)
_B__ pinocytosis
_D__ receptor-mediated endocytosis
_A__ phagocytosis
_C__ secretion
A. ingestion of large particles such as debris or bacteria
B. ingestion of liquids
C. ribosomes synthesize proteins on the Rough Endoplasmic Reticulum and thread them into the lumen.
From there they are sent to the Golgi Apparatus where they are processed and sent in vesicles to
the outside of the cell.
D. cells take up materials that are bound to specific cytoplasmic receptors.
4. The first lines of defense of the innate immune response are (2 pts)
A. skin
B. mucous membranes
C. ciliated respiratory tract
D. secretions such as tears and saliva which contain enzymes
E. all of the above
5. The normal microbiota can never cause any infections in the host, these are healthy bacteria which keep the
host in a state of equilibrium. (1 pt)
A. TRUE
B. FALSE
6. The granulocytes important in the innate immune response are the neutrophils. (1 pt)
A. TRUE
B. FALSE
7. Macrophages are (2 pts)
A. the professional phagocyte, first to arrive at the scene of an infection
B. important in the process of inflammation
C. may be activated by T cells to form more potent chemicals to destroy bacteria, such as nitric oxide
D. drawn to an area of inflammation by chemokines or pro-inflammatory cytokines
E. all of the above
F. b and d
G. b, c, and d
8. Toll-like receptors (2 pts)
A. are used by cells to identify the presence of microbes
B. are pattern recognition receptors, bind specific parts that are unique to bacteria
C. when bound activate gene expression such as the production of cytokines
D. are only found in cells that are infected with virus, specifically RNA viruses
E. all of the above
F. a and b
G. a, b, and c
9. The complement system (2 pts)
A. consists of proteins that are found in the blood and tissues in an inactivated state until needed
B. can be activated by the presence of antibody bound to antigen
C. when activated results in cell lysis and inflammation
D. promotes the phagocytosis of bacteria by coating them in complement protein C3b
E. a and b
F. b and c
G. all of the above
10. If a body cell is producing interferons, then this cell may be infected with a single-stranded RNA animal
virus. (1 pt)
A. TRUE
B. FALSE
11. In the stages of phagocytosis (2 pts)
A. attachment of the phagocyte to the targeted pathogen is essential and may occur via binding to C3b
receptors
B. the fusion of the phagosome with the lysosome generates a structure called a phagolysosome
C. the lysosome contains digestive enzymes to degrade the ingested pathogen
D. pathogens which are able to prevent fusion of the phagosome and lysosome are resistant to
phagocytosis
E. a, b, and c
F. all of the above
12. The inflammation process (2 pts)
A. is designed to deliver the phagocytic cells to the site of injury
B. requires the production of cytokines to promote chemotaxis and diapedesis of phagocytes
C. may be activated by the complement system
D. always generates a fever response
E. a and b
F. a, b, and c
G. all of the above
13. An antigen is (1 pt)
A. a molecule that reacts specifically with an antibody or immune lymphocyte.
B. the variable region of an antibody.
C. the constant region of an antibody.
D. a cytokine.
E. None of these choices are correct.
14. Immunoglobulins (1 pt)
A. are proteins.
B. recognize and bind to foreign substances.
C. increase phagocytosis.
D. neutralize toxins.
E. All of these choices are correct.
15. Which of the following statements is FALSE? (1 pt)
A. T helper cells release cytokines.
B. T helper cells activate specific B cells.
C. T helper cells are antigen specific.
D. T helper cells kill virus-infected cells.
E. T helper cells have CD4 on the cell surface.
16. The humoral response of human immunity produces (1 pt)
A. neutrophils/polymorphonuclear cells.
B. antibody proteins.
C. complement proteins.
D. blood serum.
E. interferons
17. Which of the following is FALSE about B lymphocytes? (1 pt)
A. They develop in the bone marrow.
B. They are responsible for cell mediated immunity.
C. They are associated with antibodies.
D. Some B lymphocytes form memory cells.
E. All of these choices are true statements.
18. Dendritic cells and macrophages start the immune response by (1 pt)
A. degrading MHC class I proteins and presenting them on the surface of their cells.
B. degrading foreign proteins and presenting them on MHC class II proteins.
C. producing cytokines to recruit T helper cells.
D. activating B cells directly.
E. None of these choices are correct.
19. Clonal selection (1 pt)
A. affects only memory cells.
B. only happens to B cells as they become plasma cells.
C. occurs with both T cells and B cells.
D. happens only with B cells that produce IgE.
E. occurs in the blood stream.
20. ________________________ are descendants of activated lymphocytes with the ability to produce specific
cytokines or other protective substances. (1 pt)
A. Immature lymphocytes
B. Naive lymphocytes
C. Activated lymphocytes
D. Effector lymphocytes
E. Memory lymphocytes
21. Which of the following is NOT a feature of the cell-mediated immune response? (1 pt)
A. B cell involvement
B. MHC class I molecules
C. cytotoxic T cells
D. CD8 molecules
E. None of these are correct.
22. How long does it take for a substantial amount of antibody to accumulate after being exposed to an antigen
(1 pt)
for the first time?
A. Approximately 2 - 3 days.
B. Approximately 4 - 6 days.
C. Approximately 7 - 9 days.
D. Approximately 10 - 14 days.
E. Approximately 19 - 21 days.
23. Opsonization (1 pt)
A. is the killing of target cells by cytotoxic T cells.
B. is the secretory component of IgA.
C. helps improve phagocytosis of bacteria.
D. is the interaction that allows IgG to cross the placenta.
E. None of these choices are correct.
24. CD4 T cells are (1 pt)
A. T helper cells.
B. cytotoxic T cells.
C. macrophages.
D. B cells.
E. None of these choices are correct.
25. A plasma cell is a _____________ cell that has matured and produces _________. (1 pt)
A. T, cytokines
B. cytotoxic T, cell-killing
C. macrophage, antigens
D. B, antibodies
E. CD3, antibodies