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Coeffecient of relatedness and predictions of complex genetic influences The coefficient of relatedness (r) between two individuals is defined as the percentage of genes that those two individuals share by common descent. •MZ twins = 1.0 •DZ twins = 0.5 •Siblings = 0.5 •Parents & offspring = 0.5 •Grandparents & grand children =0.25 If a behavioral trait is under complete genetic control would we predict that r =total variability in the trait? Environmental hypothesis Two major approaches used by behavior geneticists to study relative contributions of genes & environment in the development of behavior •Hold genetic make-up constant to study effects of the environment alone (VT=VE) •cross-fostering experiments & twin studies •Hold environment constant & explore effects of genes alone (VT=VG) •selective breeding experiments •use of genetic “knock-outs” Keep in mind: •Genetic effects are usually complex, involving Pleiotropic and Polygenic effects •Environmental effects are complex involving multiple environmental factors •Complex genetic and environmental effects will be further complicated by gene/environment interactions. Taken from Personality and Individual Differences, Vol. 23, No. 1 (July 1997), pp. 169-180 Heritability: A measure of how strongly a phenotype is influenced by genetics Total phenotypic variation=VT=VG+VE+VI where: VT= total phenotypic variation observed in a (behavioral) trait VG= variation in population due to genotype VE =variation in population due to environment VI = variation in population due to interaction of VG with VE (i.e. VGxVE) Heritability (H2) H2=VG/(VG+VE+VI) = VG/VT Characteristics of H2 Heritability is standardized variance ranging from 0.0-1.0 Indicates what fraction of the total variance in a trait is due to variation in genes: •H2=0: None of the variance in the trait is influenced by genes •H2=1:Taken All of the variance in the trait is determined from Personality and Individual Differences, Vol. 23, No. 1 (July 1997), pp. 169-180 by genes Philippe Rushton Primary research interest is altruism and social learning of generosity More controversial is on race differences Rushton Phillip Psychology 1/19 /05 14 3.0 3.1 Heritability (H2) of IQ = 0.70 Average IQ by Ethnic group: African Americans 85 Latino 89 White 103 Asian 106 Jewish Americans 115 Correlation between IQ and head/brain size = 0.40 (MRI normal adults) 0.24 (MRI clinical adults) Taken from Personality and Individual Differences, Vol. 23, No. 1 (July 1997), pp. 169-180 Brain size Brain size and race Population Cubic inches Cubic centimeters 87 87 86 85 84 83 1427 1427 1410 1394 1378 1361 Mongolians Modern Caucasians Native Americans Malays Ancient Caucasians Africans Brain size and SES Men •Unskilled •Professional 1,324cc 1,468cc Women •Unskilled •Professional 1256cc 1264cc Brain size and sex •Men •Women ***However no difference in IQ ??? 1325g 1144g Taken from Personality and Individual Differences, Vol. 23, No. 1 (July 1997), pp. 169-180 1 of 6 warbler species that regularly winter in the British Isles, 4 of which are migratory Chiffchaff, Blackcap, Firecrest and Goldcrest winter Atlas 1981-1984, estimates 3,000 Blackcaps Quantifying intended flight direction