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Factors that affect allele frequencies Genetic Variation • Most traits in a population vary from one extreme to another (eg. Height, weight) Allele Frequency • How often a particular allele appears in a population. 30% of us have the brown phenotype Homozygous Individuals carry two copies of the allele, while heterozygous individuals carry one. Gene Flow • Movement of individuals between populations moves the alleles carried by the individuals • Can change the allele frequency in both populations • Can also spread new alleles that arise in one population Gene Flow Migration between habitats Population: Population: 15 blue blue (65%) (75%) 13 Green (35%) (25%) 75 Green Population: 5 blue (35%) (25%) 7 15 Green (65%) (75%) 13 Genetic Drift • Genetic Drift – The gradual change in allele frequencies due to chance. Especially strong in small populations Genetic Drift Population 17 blue (85%) 3 green (15%) Random events cause the death of some individuals Population 15 blue (93.75%) 1 green (6.25%) Bottleneck • Bottleneck - occurs when a population’s size is reduced. • Because genetic drift acts more quickly to reduce genetic variation in small populations, undergoing a bottleneck can reduce a population’s genetic variation by a great deal Cheetah Cheetahs are so closely related to each other that they do not reject skin grafts www.petsdoc.com/pics/funpages/ wildlifephotos/cheeta Northern Elephant Seal Bottleneck Effect http://www.icsi.berkeley.edu/~dbailey/gallery/image/elephant.jpg - Reduced to 20 individuals in 1896 - Now 30,000 individuals, with no detectable genetic diversity Founder Effect • Founder Effect - If a population began with a few individuals, one or more of whom carried a particular allele, that allele may come to be represented in many of the descendants. Founder Effect Access to new habitat Population 13 15 Blue (82%) (75%) 35 Green (18%) (25%) Some individuals migrate Genetic makeup of that group populate new habitat Population 82 Blue (50%) 82 Green (50%) Founder Effect • In the 1680s Ariaantje and Gerrit Jansz emigrated from Holland to South Africa, one of them bringing along an allele for the mild metabolic disease porphyria. • Today more than 30000 South Africans carry this allele and, in every case examined, can trace it back to this couple — a remarkable example of the founder effect Tristan de Cunha Islands An 1814, 15 British colonists founded a settlement on Tristan da Cunha, a group of small islands in the Atlantic Ocean, midway between Africa and South America One of the early colonists apparently carried a recessive allele for retinitis pigmentosa, a progressive form of blindness that afflicts homozygous individuals. Of the founding colonists' 240 descendants on the island in the late 1960s, 4 had retinitis pigmentosa. The frequency of the allele that causes this disease is ten times higher on Tristan da Cunha than in the populations from which the founders came.