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Organic Compounds Overview a.k.a. Biomolecules Overview Basics • Organic compounds contain carbon (C) and hydrogen (H) • In living things, they are also called “biomolecules.” • 4 main types: – – – – Carbohydrates Proteins Lipids Nucleic Acids Carbohydrates (polymers) • Monomers (building blocks) =monosaccharides =Single sugars Ex) glucose, fructose, ribose • 2 monosaccharides make a disaccharide. (ex. sucrose, lactose) • 3+ make a polysaccharide (ex. starch) Chemical Makeup • Carbon (C), Hydrogen (H) and Oxygen (O) in a 1:2:1 ratio • Standard chemical formula (for monosaccharides): CxH2xOx • Ex) Glucose=C6H12O6 Functions • Short term energy storage – Raw fuel for cellular respiration • Structure (in plants’ cell walls, in animals=chitin (exoskeletons) Examples • In animals: – Glucose – Glycogen (a polysaccharide that provides longer energy storage.) – Chitin (compound in exoskeletons) • In plants: – Glucose & Fructose – Starch – Cellulose (in cell walls) Other info: • Smaller molecules are more soluble in water than larger ones. • Deoxyribose & ribose are sugars in nucleic acids (DNA & RNA) Proteins (polymers) • Building blocks =amino acids (20) • 12 amino acids can be produced by the body. • 8 must be obtained from food (essential amino acids) • Amino acid chain=polypeptide Chemical Makeup • Carbon, Oxygen, Hydrogen, Nitrogen • All have an amino group (NH2) • Complex! Structure (see p. 45) • Have 3-dimensional structure • 4 levels: – Primary (single chain) – Secondary (alpha helix or pleated sheet) – Tertiary (globular or fibrous) caused by hydrophobic/hydrophillic interactions or by disulfide bonds – Quaternary (2 or more polypeptides fit together) Functions • • • • • • • Structural (hair, ligaments) Contractile (muscles) Enzymes Defensive (immune system) Signal (coordinate body functions) Receptor (on cell membranes) Transport (hemoglobin carries oxygen) Lipids (polymers) • Monomers (building blocks) =1 glycerol + 3 fatty acid chains • They are hydrophobic (water-”fearing”) Chemical makeup • Carbon, Hydrogen, and Oxygen • Glycerol is an alcohol w/ 3 -OH groups. • Fatty acid is a hydrocarbon chain with a -COOH group Lipids-Examples & Functions • Fat (long term energy storage, insulation, cushioning) • Phospholipids (cell membranes)--have 2 fatty acids + phosphate group (PO4) • Cholesterol (animal cell membranes, starting point for other steroids, incl. sex hormones) More about fats • Saturated fats – solid at room temperature – From animals – Contain the maximum # of hydrogens (i.e. no double bonds) • Unsaturated fats – Liquid at room temperature – From plants – Contain less than the max. # of H (due to double bonds.) Nucleic Acids (polymer) • Monomers (building blocks)= Nucleotides • Nucleotide= – 5-carbon sugar (deoxyribose or ribose) – Phosphate group – Nitrogenous base (A, C, T (or U), G) Nitrogenous Bases • • • • • • A=Adenine T=Thymine U=Uracil C=Cytosine G=Guanine Pairing: – A & T, C & G (in DNA) – A & U, C & G (in RNA) 2 types of nucleic acids • DNA (deoxyribonucleic acid) – Form genes, which code for proteins (function) – Double stranded (double helix) – A, C, T, G • RNA (ribonucleic acid) – Used to help make proteins (function) – Single helix – A, C, U, G