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Define the following terms or describe their role in the immune system: HERD IMMUNITY EPIDEMIC ENDEMIC PANDEMIC Vaccination Explain how a vaccine leads to the change in antibody production shown on the diagram below. B cells T cells Use this area to draw a flow chart to show how B Use this area to draw a flow chart to show how T cells produce the humoral response. Include the cells produce cell mediated immunity. Include the following terminology: specific binding, clonal following terminology: antigen presentation, selection, clonal expansion, plasma cells, memory specific binding, clonal selection, clonal expansion, cells. T killer cells, T helper cells and T memory cells. Types of immunity Define the following terms or describe their role in the immune system: Fill in the table below to give some examples of different types of immunity ANTIBODY Active PLASMA CELLS Passive Natural ANTIGEN PRESENTATION Artificial CLONAL SELECTION CLONAL EXPANSION Antibodies VACCINATION Draw a diagram of an antibody and label the following parts, giving ATTENUATED their function where appropriate: heavy chain, light chain, disulphide links, variable region, constant region, hinge. Phagocytosis Finish this diagram to show how a macrophage engulfs and digests a pathogen (and its antigens). Label the diagram with the words: phagosome, lysosome, phagolysosome, exocytosis. Antibody effects Antibodies meet with an antigen and bind with it. Give three ways that the antibody can deal with the antigen. 1. 2. 3.