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Chapter 9 Cellular Respiration.notebook February 22, 2016 Chapter 9 Cellular Respiration Key Concepts What is cellular respiration? What happens during the process of glycolysis? What are the two main types of fermentation? How are chemical energy and food related? we get chemical energy from the food we eat food serves as a source of energy How much energy is actually in food? from one gram sugar (glucose C6H12O6) when burned in the presence of O2, releases 3811 calories of heat energy "burning calories" release energy from glucose and other food compounds Calorie amount of energy needed to raise the temperature of 1 gram of water 1 degree Celsius a unit of energy food labels "C" are actually a kilocalorie 250 cal candy bar = 250,000 calories to gain 1 lb of fat = 3500 extra calories above your needs Cellular Respiration process that releases energy by breaking down glucose and other food molecules in the PRESENCE of oxygen occurs in the cytoplasm and the mitochondria Equation 6O2 + C6H12O6 6CO2 + 6H2O + Energy Three stages to cellular respiration: Glycolysis, Krebs Cycle, Electron Transport Each of the three stages of cellular respiration captures some of the chemical energy available in food and uses it to produce ATP (the cell's basic energy source) 1. Glycolysis "breaking glucose" occurs in the cytoplasm breaks down 1 molecule of glucose in half, producing 2 molecules of pyruvic acid, a 3 carbon compound Where does it show energy being used? In the beginning to start glycolysis, 2 molecules of ATP are used creating 2 ADP. When glycolysis is complete, 4 ATP molecules have been produced which results in a net gain of 2 ATP. In glycolysis, highenergy electrons, are passed to an electron carrier called NAD+ to create a molecule of NADH. NADH will hold these electrons until it can be transferred to another molecule The process of glycolysis is so fast that cells can produce 1000's of ATP in a few milliseconds. We will be discussing the other two stages of Cellular Respiration in the next section Glycolisis occurs in a different manner when there is no O2. Anaerobic "not in air" rxn that can occur without oxygen http://www.ck12.org/biology/Fermentation/enrichment/Fermentation/?referrer=concept_details&conceptLevel=at+grade&conceptSource=ck12 Fermentation releases energy from food molecules by producing ATP in the absence of oxygen During fermentation, cells convert NADH to NAD+ by passing he electrons back to pyruvic acid so glycolysis can continue to happen to produce ATP. Two types: Alcoholic Fermentation produces alcohol and CO2 as waste products produces NAD+ as an electron carrier Equation pyruvic acid + NADH alcohol + CO2 + NAD+ Used by yeast and a few microorganisms When the yeast in the bread dough runs out of O2, it begins to ferment, which produce gas bubbles = CO2, alcohol is evaporated as something is baked Lactic Acid Fermentation pyruvic acid accumulates and due to glycolysis it produces lactic acid and renews NAD+ NAD+ needed so glycolysis can continue Equation pyruvic acid + NADH lactic acid + NAD+ When your muscles use up the oxygen in your muscles, your body can not produce enough ATP that is needed. That is why you breathe harder when you are working out. Your body is trying to keep up with the supply of oxygen that is needed. Your body now produces ATP through lactic acid fermentation. The product of latic acid fermentation is ATP and latic acid which caused the pain in your muscles. You may feel this pain for only a few seconds or for a few days. The pain goes away when the oxygen is replenished. Why is lactic acid fermentation considered anaerobic and glycolysis is not? Lactic acid occurs without oxygen while glycolysis can occur with oxygen. Dec 228:53 AM 1 Chapter 9 Cellular Respiration.notebook February 22, 2016 92 The Krebs Cycle and Electron Transport Key Concepts What happens during the Krebs cycle? How are highenergy electrons used by the electron transport chain? https://www.youtube.com/watch?v=F6vQKrRjQcQ Anaerobic = no oxygen Aerobic = oxygen The Krebs Cycle Most of energy (about 90%) from the glucose is unused and locked into the he electrons of pyruvic acid. To extract this energy the cell uses O2 as a electron acceptor. Oxygen is required for the final steps of cellular respiration. Citric acid is the first compound produced in the Krebs Cycle, so it is also known as the Citric Acid Cycle. Summary: In the presence of oxygen, pyruvic acid produced in glycolysis is passed to the second stage of cellular respiration, the Krebs Cycle. Pyruvic acid is broken down into carbon dioxide in a series of energyextracting reactions. Krebs Cycle occurs in mitochondrial matrix. Steps in the Krebs Cycle 1. Pyruvic acid from glycolsis enters the mitochondrion. 2. One Carbon from pyruvic acid becomes part of the molecule CO2, which will be released into the air later. 3. The other 2 carbon atoms are used to create a compound called coenzyme A. 4. Coenzyme A joins a 2 carbon molecule to form acetylCoA. 5. The actyl group adds 2 carbon to a 4 carbon molecule which produces a 6 carbon molecule called citric acid. 6. Now, CO2 is released. 7. Electrons are added changing NAD+ to NADH. 8. Citric acid is broken down into a 5carbon compound. 9. Once again C is removed to form CO2 and it is released. 10. Electrons join with NAD+ and FAD. 11. 1 molecule of ATP is formed. 12. 5 different spots 2 he electrons are accepted by he carriers changing NAD+ to NADH and FAD to FADH2. The Krebs Cycle produces all of the CO2 that is exhaled from your breathing. All of the electrons are used to create huge amounts of ATP. Electron Transport The third and final stage of cellular respiration, the electron uses he electrons from the Krebs cycle to convert ADP to ATP. This takes place in the inner membrane of the mitochondrion. He electrons are passed from NADH and FADH2 to the electron transport chain from one carrier protein to the next. At the end of chain is an enzyme that combines electrons with hydrogen ions and oxygen to form H2O which is a waste product. The enzyme ATP synthase in the membrane turns ADP into ATP. Glycolysis produces just 2 ATP molecules per molecule of glucose in the presence of O2. Energy is used to import the NADHs from glycolysis from the cytoplasm into the mitochondrion. Total ATP created through 3 stages of cellular respiration = 36 Figure 98 shows production process of ATP totals. Jan 68:57 AM 2