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Chapter 2 The Anatomy of the Brain The Systems, Structures, and Cells that Make Up Your Nervous System This multimedia product and its contents are protected under copyright law. The following are prohibited by law: • any public performance or display, including transmission of any image over a network; • preparation of any derivative work, including the extraction, in whole or in part, of any images; • any rental, lease, or lending of the program. Copyright © 2007 by Allyn and Bacon General Layout of the Nervous System  Central Nervous System (CNS)  Brain (in the skull)  Spinal Cord (in the spine)  Peripheral Nervous System (PNS)  Located outside of the skull and spine  Serves to bring information into the CNS and carry signals out of the CNS Copyright © 2007 by Allyn and Bacon General Layout of the Nervous System  PNS – 2 divisions  Somatic   Nervous System Afferent nerves (sensory) Efferent nerves (motor)  Autonomic  Nervous System Sympathetic and parasympathetic nerves Copyright © 2007 by Allyn and Bacon Autonomic Nervous System Sympathetic  “fight or flight”  Second stage neurons are far from the target organ  Parasympathetic  “rest and restore”  Second stage neurons are near the target organ  Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon Meninges, Ventricles, and CSF  CNS - encased in bone and covered by three meninges  Dura mater - tough outer membrane membrane - weblike  Pia mater - sticks to CNS surface  Arachnoid  Cerebrospinal fluid (CSF)  Fluid serves as cushion Copyright © 2007 by Allyn and Bacon Protecting the Brain  Chemical protection blood-brain barrier – tightly-packed cells of blood vessel (endothelial cells) walls prevent entry of many molecules  The  Physical protection  Skull  Meninges  Cerebrospinal fluid (CSF) Copyright © 2007 by Allyn and Bacon Cells of the Nervous System Generally two types  Neurons – specialized for reception, conduction, and transmission  Glial cells – Support cells; outnumber neurons by 10 to 1.  Copyright © 2007 by Allyn and Bacon Anatomy of Neurons  Neurons     – structural classes Multipolar Unipolar Bipolar Interneurons Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon Anatomy of Neurons  Nuclei – clusters of cell bodies in the CNS  Ganglia – clusters of cell bodies in the PNS  Tracts – bundles of axons in the CNS  Nerves – bundles of axons in the PNS Copyright © 2007 by Allyn and Bacon Glial Cells: The Forgotten Majority  Myelin producers Oligodendrocytes (CNS) Schwann cells (PNS) – largest, many functions (composed the blood-brain barrier)  Microglia – smallest, involved in response to injury or disease  Astrocytes Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon Terminology Note CNS MyelinOligodendrocytes providing glia PNS Schwann Cells Clusters of Nuclei cell bodies (singular nucleus) Ganglia Bundles of Tracts axons Nerves (singular ganglion) Copyright © 2007 by Allyn and Bacon Neuroanatomical Directions Anterior (rostral) – towards the nose  Posterior (caudal) – towards the tail  Dorsal – towards the surface of the back or the top of the head  Ventral – towards the surface of the chest or the bottom of the head  Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon The Five Divisions of the Brain Copyright © 2007 by Allyn and Bacon Major Structures of the Brain  Myelencephalon = medulla  Composed largely of tracts  Origin of the reticular formation  Metencephalon  Many tracts  Pons – ventral surface  Cerebellum - coordination Copyright © 2007 by Allyn and Bacon Major Structures of the Brain  Mesencephalon  Tectum (dorsal surface) Inferior colliculi – audition Superior colliculi - vision  Tegmentum (ventral) – 3 ‘colorful’ structures Periaqueductal gray – analgesia Substantia nigra – sensorimotor Red nucleus– sensorimotor Copyright © 2007 by Allyn and Bacon Major Structures of the Brain  Diencephalon  Thalamus – sensory  Hypothalamus    relay nuclei Regulation of motivated behaviors Controls hormone release by the pituitary Telencephalon  Cerebral cortex  Limbic system  Basal ganglia Copyright © 2007 by Allyn and Bacon Telencephalon – Cerebral Cortex Convolutions serve to increase surface area.  Longitudinal fissure – a groove that separates right and left hemispheres  Corpus callosum – largest hemisphere-connecting tract  Copyright © 2007 by Allyn and Bacon Limbic System Regulation of motivated behaviors  “a circuit of midline structures that circle the thalamus”  Consists of   Primitive cortex - hippocampus and cingulated cortex  Subcortical structures - mammillary bodies, amygdala, fornix, septum Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon Copyright © 2007 by Allyn and Bacon