Download LICEO SCIENTIFICO FRANCESCO REDI

LICEO SCIENTIFICO
FRANCESCO REDI
Z E N K E R ’ S D E G E N E R AT I O N
TEACHER:
VA N N U C C I N I E L I S A
S T U D E N T: M E N C U C C I M A R C O
MUSCLE
It’s a soft tissue found in most animals. Muscle cells contain protein
filaments of actin and myosin then slide past one another, producing
a contraction.
MUSCLE’S TYPES:
INVOLUNTARY
A muscle that contracts without
conscious control.
Ex.: stomach
VOLUNTARY
Muscle whose action is normally controlled by an individual’s will
Ex.: biceps and triceps
A tissue can incur in a
DEGENERATION
That could be:
 True degeneration: when there is actual chemical change of the tissue
itself;
 Infiltration: when the change consists of the deposit of abnormal
matter in the tissues.
WHO IS FRIEDRICH ALBERT VON ZENKER?
Zenker
(13
March
1825,Dresden-13
June
1898,
Mecklenburg) was a German pathologist and physician,
celebrated for his discoveries in the diseases’s field.
ZENKER’S DEGENERATION
It’s a severe hyaline degeneration or necrosis of skeletal muscles, and
occurs in severes cases of toxaemia as typhoid fever.
NECROSIS
It’s a form of cell injury wich results in the premature death of cells in
living tissue by autolysis.
 ONCOSIS: it is an accidental necrosis.
 APOPTOSIS: a voluntary necrosis.
CAUSES OF ZENKER’S DEGENERATION
 Thoxemia: presence of toxins in the blood (commonly called
bacteremia), wich is normally a sterile environment.
 By the action of lactic acid wich is formed by the living muscle under
the stimolation of infecting bacteria, and the accumulation of this
acid could be helped by a defective circulation
TREATMENT:
 Debridement: removal of dead tissue by surgical or non surgical
means, and in extremes cases there could be the amputation of
affected limbs.
 Some treatments involve identification of the harmful agent followed
by the use of immunosuppresive therapies.
 Stamina cells, wich are used just in sperimentals treatments.