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Download Cellular Respiration Chapter 8 Outline Glycolysis Transition
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Outline Cellular Respiration Chapter 8 • • • • • • Mader: Biology 8th Ed. Mader: Biology 8th Ed. TA p132 Cellular Respiration • A cellular process that requires oxygen and gives off carbon dioxide. – Most often involves complete breakdown of glucose to carbon dioxide and water. ! Energy within a glucose molecule is released slowly so that ATP can be produced gradually. ! NAD+ and FAD are oxidation-reduction enzymes active during cellular respiration. Mader: Biology 8th Ed. Glycolysis Transition Reaction Citric Acid Cycle Electron Transport System Fermentation Metabolic Pool – Catabolism – Anabolism Fig. 8.1 Glucose Breakdown • • • • During glycolysis, glucose is broken down in cytoplasm to two molecules of pyruvate. During transition reaction, pyruvate is oxidized, NADH is formed, and waste carbon dioxide is removed. Citric acid cycle results in NADH and FADH2, release of carbon dioxide, and production of additional ATP. Electron transport chain produces 32 or 34 molecules of ATP. Mader: Biology 8th Ed. Glucose Breakdown Glycolysis • • Mader: Biology 8th Ed. Two ATP are used to activate glucose that splits into PGAL. Oxidation of PGAL and subsequent substrates results in four high-energy phosphate groups, which synthesize four ATP. – Substrate-Level Phosphorylation Mader: Biology 8th Ed. Glycolysis Inside the Mitochondria • Mader: Biology 8th Ed. Fig. 8.3 End product of glycolysis, pyruvate, enters the mitochondria, where it is oxidized to carbon dioxide during the transition reaction and citric acid cycle. – CO and ATP are transported out of 2 mitochondria into the cytoplasm. Mader: Biology 8th Ed. Fig. 8.4 Mitochondrion Structure and Function Transition Reaction • Mader: Biology 8th Ed. Mader: Biology 8th Ed. Citric Acid Cycle • Originally called Krebs cycle. Mader: Biology 8th Ed. Connects glycolysis to the citric acid cycle. Electron Transport System • As electrons pass down the electron transport system, energy is captured and ATP is produced. – Oxidative phosphorylation refers to the production of ATP as a result of energy released by the electron transport system. Mader: Biology 8th Ed. Fig. 8.8 Mader: Biology 8th Ed. Fig. 8.10 Fermentation • Glycolysis followed by reduction of pyruvate by NADH to either lactate or alcohol and carbon dioxide. – Anaerobic pathway. – Can provide rapid burst of ATP. ! Common in muscle cells. Mader: Biology 8th Ed. Fermentation Metabolic Pool • Mader: Biology 8th Ed. Carbohydrates, fats, and proteins can be used as energy sources. – Catabolism produces molecules that can also be used for anabolism and other compounds. ! All reactions in cellular respiration are part of a metabolic pool, and their substrates can be used for catabolism or anabolism. Mader: Biology 8th Ed. Fig. 8.11 Review • • • • • • Glycolysis Transition Reaction Citric Acid Cycle Electron Transport System Fermentation Metabolic Pool – Catabolism – Anabolism Mader: Biology 8th Ed. Mader: Biology 8th Ed.