Download Glycolysis Puzzle: Concept Map of "Splitting of Glucose"

Glycolysis Puzzle: Concept Map of "Splitting of Glucose"
Glucose = 6 carbon sugar. This 6 C compound is made possible by photosynthesis!
Glucose
1
A phosphorylation reaction adds a_____ group to the
glucose.
This reaction uses ____ ATP
[delta G = -8.0 kcal/mol]
2
2
This 6 C compound undergoes an enzyme catalyzed
isomerization, i.e., a rearrangement of functional groups.
[delta G = -0.6 kcal/mole]
3
Phosphorylation reaction uses ________ for substrate level
phosphorylation.
[delta G = -5.3 kcal/mole]
In this reaction, the 6 C sugars is split into 2,
3 carbon compounds.
[delta G = -5.3 kcal/mole]
4
5
In this reaction, isomerase converts 1 of 3C molecules so
that there are two molecules of glyceraldehydes 3phosphate
[delta G = +0.6 kcal/mole]
Only one of two
molecules of
glyceraldehydes is
shown here.
Recognize that the
following
reactions happen
to the other
molecule.
6
In reaction 6, the enzyme catalyzes two sequential
reactions:
(1) The glyceraldehyde 3 phosphate is oxidized. The
energy resulting from the oxidation of this 3 C compound
is conserved by the reduction of the coenzyme
_______________ to form
____________________.
This coenzyme has "reducing potential."
6
7
(2) In place of the H that is removed, an inorganic
PO4 group is added, producing a 3C compound that
has _______ PO4 groups.
[delta G = -0.4 kcal/mole]
The phosphate group added above is transferred at
this reaction step to ADP to produce ATP via
substrate level phosphorylation.
[delta G = +0.3 kcal/mole]
At this point in glycolysis, _________ATP’s have
been used and ________ATP’s have been produced
8
This 3 C compound now has ______PO4 group(s).
This 3 C compound undergoes an isomerization
reaction which relocates PO4 group from the 3rd to
2nd carbon
[delta G = + 0.2 kcal/mole]
9
A molecule of water is removed causing a double
bond to form within the C backbone. In this
chemical state, the phosphate bond isdestabilized,
which facilitates the next reaction.
[delta G = -0.8 kcal/mole
10
The PO4 group is removed and transferred to ADP
resulting in the production an ______molecule via
substrate level phosphorylation.
[delta G = -4.0 kcal/mole]
The end product of glycolysis is called pyruvate.
For every one molecule of glucose, there are
__________________ molecules of pyruvate
produced.
Identify which reactions (by number) that are exergonic:
Identify which reactions (by number) that are endergonic:
Is the overall glycolysis reaction an exergonic or endergonic reaction?
Pyruvate has two biochemical fates, depending upon whether or not oxygen is present.
In the absence of oxygen, anaerobic respiration (fermentation) occurs.
In animal cells ________________________ is reduced to lactic acid (lactate)
By the oxidation of the coenzyme __________________________
In yeast cells, a two step reaction occurs in which _______________________ is
reduced to ethanol, and generates CO2.
For both types of cells, the main purpose of anaerobic respiration is to regenerate the
oxidized state of the coenzyme _________________________, which then can be used
in ___________________(Hint” “splitting sugar reaction”), resulting in ____________
net molecules of ATP.
Anaerobic respiration buys some time for animal cells.
"Happy hour" is made possible through the anaerobic respiration of yeast!