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Transcript
Immun 441 Practice Questions Set #1 AB Discussion section 1. What is the evolutionary purpose of having both an innate and adaptive immune system that function as they do in humans? 2. Name 3 different types of barriers (mechanical, chemical, and microbial) that protect us from pathogens and list the key features for each category. 3. A dendritic cell phagocytoses a gram-negative bacteria. Which PAMP(s) may be detected? Which innate immune receptor will be detecting the PAMP(s)? 4. What type of pathogens do surface TLRs recognize? Endosomal TLRs? 5. Why is it logical that the TLRs are located where they are? 6. What cellular mechanisms and gene expression programs do TLRs activate? 7. Which cells are considered to be Professional Antigen Presenting (APC) cells and what differentiates them from ‘non-professional’ antigen presenting cells. 8. Describe the similarities and differences between the three types of programmed cell death. 9. Give examples of pathogens that would undergo the Classical, Lectin, and Alternative pathways. 10. Name 3 forms of regulation within the complement cascade.