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GENES AND CHROMOSOMES I. Interpretation of Mendel’s laws with reference to meiosis. A. alleles carried on homologs (sketch these) 1. homologs segregate during meiosis 2. gametes carry one allele or the other, but not both B. when two pairs of alternate alleles carried on two pairs of homologs 1. homologs separate during meiosis I 2. chromatids separate during meiosis II 3. alleles assort independently II. Linkage A. definition of linked genes: B. relation to Mendel’s 2nd Law: C. crossing over and genetic recombination 1. parental genotypes and nonparental genotypes 2. genetic maps based on frequency of crossing over III. Sex chromosomes and linkage A. X and Y chromosomes 1. relation to males and females 2. difference in genetic information content B. Effect of Y chromosome on phenotype of male 1. lack of dominance effect 2. examples of mutations showing sex linkage a. b. IV. Mutation A. definition B. types 1. point: deletion, insertion 2. chromosomal rearrangements (aberrations): inversion, translocation