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Transcript
(1) DIVISION AND
DIFFERENTIATION IN HUMAN CELLS
(F) Cancer
Cells
(A)
Somatic
cells
(B)
Differentiation
in cells
Human
Cells
(C) Stem
cells
(E) Uses
of stem
cells
(D)
Germline
cells
DIVISION AND DIFFERENTIATION
IN HUMAN CELLS (F)
 Define
how cancer develops in the
body
 Define how a tumour can develop in
the body
 State 2 characteristics of a tumour
 State the consequence of one of
these features
UNCONTROLLED CELL DIVISION
Normal cell division
Cancerous cell division
Day 1
Day 2
Day 3
Day 4
cells
cells
cells
cells
Day 1
Day 2
Day 3
Day 4
cells
cells
cells
cells
Day 5
cells
Day 5
cells
Cancer: Unregulated Cell Division - YouTube
• They do not respond to normal regulatory signals that
would instruct them to stop dividing when necessary.
• They lose the molecules on their surface that would
normally hold them in place and can therefore be
detached from their neighbours, causing the cells to
spread (malignant tumour).
DIFFERENCES BETWEEN CANCER AND NORMAL CELLS
WHAT
HAPPENS WHEN CELL DIVISION
GOES WRONG?
Cell division is very strictly controlled by genes.
However, if the gene that controls cell division is
incorrectly triggered, then cell division can occur
uncontrollably.
 This means cells will continue to grow and grow and
grow. This is cancer.
 Cancer cells divide excessively to produce a mass
of abnormal cells (called a tumour).

These cells do not respond to regulatory signals and
 May fail to attach to each other.


If the cancer cells fail to attach to each other
they can spread through the body to form
secondary tumours.
CANCER – SUMMARY VIDEO (5 MINUTES)

Cancer: from a healthy cell to a cancer cell