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Guilfoyle Course - AP Bio EQ: Relationships are very important in biology, how many relationships can you identify/explain within the characteristics of life? Elaborate on the need for these relationships? Predict how they evolved. Steps Focus Catalyst Goal/Objective Common Core 21st Century Skill STEM Technology Goal/Objective Wednesday February 25 Catalyst - Heredity Olympics See Separate Sheet for Unit Goal/Objectives (College Board and NCSCOS) W1 - Write arguments to support claims with clear reasons and relevant evidence W4 - Produce clear and coherent writing W7 - Research R1 - Cite textual evidence Team work Deductive reasoning Promethean board See Separate Sheet for Unit Goal/Objectives (College Board and NCSCOS): Big Idea 3 - Genetics: Living systems store, retrieve, transmit and respond to information essential to life processes. EU 3.A: Heritable information provides for continuity of life. EK 3.A.2: In eukaryotes, heritable information is passed to the next generation via processes that include the cell cycle and mitosis or meiosis plus fertilization. EK 3.A.3: The chromosomal basis of inheritance provides an understanding of the pattern of passage (transmission) of genes from parent to offspring. EK 3.A.4: The inheritance pattern of many traits cannot be explained by simple Mendelian genetics. LO 3.10 represent the connection between meiosis and increased genetic diversity necessary for evolution. LO 3.11 evaluate evidence provided by data sets to support the claim that heritable information is passed from one generation to another generation through mitosis, or meiosis followed by fertilization. LO 3.12 construct a representation that connects the process of meiosis to the passage of traits from parent to offspring. LO 3.13 pose questions about ethical, social or medical issues surrounding human genetic disorders. LO 3.14 apply mathematical routines to determine Mendelian patterns of inheritance provided by dat LO 3.15 explain deviations from Mendel’s model of the inheritance of traits. LO 3.16 explain how the inheritance patterns of many traits cannot be accounted for by Mendelian genetics. LO 3.17 describe representations of an appropriate example of inheritance patterns that cannot be explained by Mendel’s model of the inheritance of traits. State that meiosis is a reduction division of a diploid nucleus to form haploid nuclei. Define homologous chromosomes . Define gene , allele and genome . Outline the process of meiosis, including pairing of homologous chromosomes and crossing over, followed by two divisions, which results in four haploid cells. Describe the behaviour of the chromosomes in the phases of meiosis. Outline the formation of chiasmata in the process of crossing over. Explain how crossing over between non-sister chromatids of a homologous pair in prophase I can result in an exchange of alleles. Explain how meiosis results in an effectively infinite genetic variety in gametes through crossing over in prophase I and random orientation in metaphase I. Distinguish between autosomes and sex chromosomes . State Mendel’s law of independent assortment. Explain the relationship between Mendel’s law of independent assortment and meiosis. State that, karyotyping, chromosomes in pairs according using to their sizecollected and structure Explain theinprocess of karyotyping; Stateare thatarranged karyotyping is performed cells by chorionic villus sampling or amniocentesis, for pre-natal diagnosis of chromosome abnormalities SWBAT - APICA SWBAT - APICA Agenda Independent Work CFU Closure Homework Self-Reflection Explain that non-disjunction can lead to changes in chromosome number, illustrated by reference to Down syndrome (trisomy 21) Analyse a human karyotype to determine gender and whether non-disjunction has occurred Define genotype , phenotype , dominant allele , recessive allele , codominant alleles , locus , homozygous , heterozygous , carrier and test cross . Determine the genotypes and phenotypes of the offspring of a monohybrid cross using a Punnett grid. Calculate and predict the genotypic and phenotypic ratios of offspring of dihybrid crosses involving unlinked autosomal genes. Outline the use of the chi-squared test in analyzing monohybrid and dihybrid crosses using given values. Use chi square analysis to analyze data from monohybrid and dihybrid crosses to determine "goodness of fit" Calculate and predict the genotypic and phenotypic ratio of offspring of dihybrid crosses involving unlinked autosomal genes. Describe incomplete dominance as a mode of inheritance Describe ABO blood groups as an example of codominance and multiple alleles. State that some genes have more than two alleles (multiple alleles). Define sex linkage . Describe the inheritance of color blindness and hemophilia as examples of sex linkage. State that a human female can be homozygous or heterozygous with respect to sex-linked genes. Explain that female carriers are heterozygous for X-linked recessive alleles. Predict the genotypic and phenotypic ratios of offspring of monohybrid crosses involving any of the above patterns of inheritance. Define polygenic inheritance . Explain that polygenic inheritance can contribute to continuous variation using two examples, one of which must be human skin colour. Define linkage group . Explain an example of a cross between two linked genes. Identify which of the offspring are recombinants in a dihybrid cross involving linked genes. Explain how the sex chromosomes control gender by referring to the inheritance of X and Y chromosomes in humans. State that some genes are present on the X chromosome and absent from the shorter Y chromosome in humans. Define sex linkage . Describe the inheritance of adrenoleukodystropy as an example of sex linkage. State that a human female can be homozygous or heterozygous with respect to sex-linked genes. Explain that female carriers are heterozygous for X-linked recessive alleles. Predict the genotypic and phenotypic ratios of offspring of monohybrid crosses involving sex linkage. Deduce the genotypes and phenotypes of individuals in pedigree charts. Catalyst - Heredity Olympics Flipchart - Heredity Olympics Enrichment and formatives embedded in flipchart Activity - Heredity Olympics TOTD - Meiosis Quest Corrections reviews and enrichment Individual consultations during the independent practice portion of the lesson TOTD - Todays Meet Reading log and Biolog