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Transcript
Active Transport &
Homeostasis
Life Science: Molecular
Membrane Proteins
Transporters are transmembrane proteins
that use energy to move molecules across a
membrane.
Active Transport
Active transport is the movement
of molecules through a membrane
against a concentration difference.
Low
Concentration
Cell
Membrane
High
Concentration
Low
Concentration
Cell
Membrane
High
Concentration
Transmembrane Pumps
Protein pumps use energy to move
molecules such as calcium, potassium, and
sodium ions across the membrane against a
concentration gradient.
– sodium-potassium pump
• pumps sodium out
• pumps potassium in
Active Transport
Active Transport
Larger molecules can be transported by movements
of the cell membrane known as bulk transport.
– Endocytosis is the process of taking material into the
cell by infolding of the cell membrane.
• phagocytosis - cell eating
• pinocytosis - cell drinking
– Exocytosis is a process of releasing large amounts of
materials from the cell.
Active Transport
Homeostasis
• Homeostasis means maintaining a constant
internal environment.
• Cells need to maintain a narrow range of
conditions to stay alive.
–
–
–
–
–
temperature
pH
salinity
minerals
glucose
Hypothalamus
• Hypothalamus = master nerve control center
➡ receives information about internal conditions from
nervous system
➡ releases hormones to maintain homeostasis
• Pituitary gland = master endocrine gland
➡ secretes broad range of hormones
to regulate other glands
hypothalamus
in the body
pituitary
Chemical Controls
Neurotransmitters released by neurons
➡ Hormones released by endocrine glands
➡
endocrine gland
neurotransmitter
axon
hormone
carried by blood
receptor proteins
receptor proteins
target cell
Feedback
• There are two ways to maintain homeostasis
– Positive feedback
– Negative feedback
Maintaining Homeostasis
hormone 1
lowers
body condition
gland
high
specific body condition
low
raises
body condition
gland
hormone 2
Negative Feedback
Model
Blood Osmolarity
ADH
pituitary
promotes
water
reabsorption
osmoreceptors in
hypothalamus
high salt
increase
thirst
nephron
Osmoregulation
low blood pressure
nephron
adrenal
gland
promotes
sodium
reabsorption
nephron
(JGA)
renin
aldosterone
angiotensin
JuxtaGlomerular
Apparatus