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Transcript
Thymus Gland,It’s Hormones, Structure,Functions !! THYMUS GLAND Thymus is a specialized primary lymphoid organ of the immune system. It is very important in the maturation of T cells. This is responsible for the immune system. It is the link between the endocrine system and the immune system. LOCATION OF THYMUS GLAND The thymus gland is located just above the heart and posterior to the sternum. STRUCTURE OF THYMUS GLAND The thymus gland is distinguishable into an outer zone called cortex and an inner zone called medulla. The organ is composed of two types of cell called lymphocytes and reticular cells. The cortex is abundant with immature T cells which migrate to the medulla in order to mature. Other types of cells found in the thymus include small population of neutrophils, eosinophils, macrophages and B-lymphocytes. THYMUS HORMONES Thymus produces thymosin which stimulates the development of T cells. Thympoetin and thymulin makes it possible to distinguish T lymphocytes and enhances T cell Functions. Thymic humporal factor (THF) increase immune responses particularly to viruses. THYMUS GLAND FUNCTIONS Thymus provides the environment where the T cells are developed and trained to locate different antigen. The function of the thymus is to receive immature T cells that are produces in the red bone marrow and train them into functional, mature T cell that attack only foreign cell. T cell first resides within the cortex of thymus where they come in contact with epithelial cells presenting various antigens. The immature T cells that respond to the antigens are selected to survive and migrate to the medulla for apoptosis and are cleaned up by macrophages. This process is known as positive selection. Several hormone produces by thymus promote the maturation of the T cells prior to their release into the blood stream. Then the mature T cells circulate through the body where they recognized and kill pathogens, activate B cells and produce antibody. This is the general notes on Thymus Gland, It’s Structure and Functions. Thank you for reading.