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The Endocrine System The Endocrine System Function of the Endocrine System To regulate, coordinate and control your body functions using hormones. Examples of Body Functions: Growth Fertility Metabolism What are Hormones? Chemical messengers Secreted (released) by Glands into bloodstream. Proteins with a specific shape. Target Cells and Receptors All cells are exposed to hormones, but not all cells react. Target Cells – cells that have special receptors that the hormone fits in to, causing a response in that cell. Target Cells and Receptors endocrine system Gland: Pituitary Location: Brain Hormones Secreted: Growth Stimulating Hormone- stimulates elongation of the bones. Thyroid Stimulating Hormone- causes the thyroid to produce its hormone. Follicle Stimulating Hormone- stimulates development of testes and ovaries. MALFUNCTION: Gigantism- due to an oversecretion of growth hormone. Gland: Pituitary Location: Brain Gland: Thyroid Location: Neck Hormones Secreted: Thyroxin- regulates metabolism. MALFUNCTION: Goiter- enlargement of the thyroid gland due to a lack of iodine in the diet. Gland: Parathyroid Location: In the Thyroid Hormone Secreted: Parathormoneregulates calcium metabolism which is necessary for nerve function, blood clotting and proper growth of teeth and bones. Gland: Adrenals Location: On top of Kidneys Hormone secreted: Adrenalin- increases blood sugar level and accelerates heart and breathing rates during times of emergency. Fight or flight Gland: Pancreas Hormones secreted: Insulin- lowers blood sugar levels (excess glucose gets stored in the liver as glycogen). Glucagon- raises blood sugar levels (stimulates the release of sugar from the liver). MALFUNCTION: Diabetes- lack of insulin leads to high blood sugar levels. Gland: Testes Hormone secreted: Testosterone- influences the development of male secondary sex characteristics. Gland: Ovaries Hormones secreted: Estrogen- influences the development of female secondary sex characteristics. Progesteroneregulates the menstrual cycle. Feedback Mechanism Negative feedback- A type of self-regulation, operates on the principal that the level of one hormone in the blood stimulates or inhibits the production of another hormone.