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Amino Acid-Derived Hormones Of the amino acid-derived hormones, some circulate for only a few minutes while others may circulate for days. The amino acid tyrosine is the precursor for two groups of hormones: the thyroid hormones, produced in the thyroid gland; and the catecholamines (epinephrine and norepinephrine), produced in the adrenal medullae. The amino acid tryptophan is the precursor for the hormone melatonin, secreted by the pineal gland, and the hormone serotonin, which is quite widespread in the body. Some of these hormones have a circulating half-life of a few days (thyroid hormones) while some are rapidly degraded (catecholamines).