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COMMUNICABLE DISEASE NEWS Art for art’s sake? I should think so, and more so than ever at the present time. It is the one orderly product which our middling race has produced. It is the cry of a thousand sentinels, the echo from a thousand labyrinths, it is the lighthouse which cannot be hidden … it is the best evidence we can have of our dignity. E E p i gr am SPOKANE REGIONAL HEALTH DISTRICT 1101 West College Avenue Spokane, WA 99201-2095 E. M. Forster (1879–1970) FEBRUARY 2002 Norwalk in the News Here in these United States, only the common cold is reported more frequently than viral gastroenteritis as a cause of illness. Although viral gastroenteritis is caused by a number of viruses, it is estimated that Norwalk-like viruses are responsible for about 1/3 of the cases of gastroenteritis in those over 2 years of age. These viruses, also known as small round structured viruses or caliciviruses, are typically named for the location in which they were first identified, for example, Hawaii, Snow Mountain, Montgomery County and Oklahoma and the Norwalk virus is their prototype. In developing countries the percentage of individuals who have developed immunity at an early age is very high. In the U.S., the percentage increases gradually with age, reaching 50% in the population over 18. Immunity, however, is not permanent and reinfection can occur. All individuals who ingest the virus and who have not had an infection with the same or related strain within the previous 12-24 months are susceptible and can develop gastroenteritis. The infectious dose is unknown but presumed to be low. The signs and symptoms of Norwalk-like viruses are similar and usually occur 24 - 48 hours after exposure. They include nausea, vomiting, diarrhea, abdominal pain, muscle aches, headache, fatigue and low-grade fever. Symptoms typically last 24 - 48 hours and subside on their own. There are no known long- term effects after recovery from this infection. Until recently, it was though that humans were the only source for Norwalk-like viruses, but they have been found to occur often in calves and sometimes in pigs. The viruses are present in the feces of infected persons and can be readily transmitted to others when hands are not thoroughly washed after toileting. Asymptomatic carriage can occur for up to 4 weeks after illness. Raw and incompletely cooked shellfish as well as salad ingredients are the foods most often implicated in Norwalk outbreaks. People also can be infected by drinking water contaminated by sewage containing one of these viruses or by consuming ice made from contaminated water. There is some evidence that the viruses also can be transmitted by aerosolized vomitus. The objective of treatment is to replace fluids and electrolytes. People with diarrhea who are unable to take fluids by mouth because of nausea may need intravenous fluids, especially small children. Antidiarrheal medications are generally not given, as they may prolong the infectious process. Antibiotic therapy is not effective. The U.S. Centers for Disease Control and Prevention estimates that more than 180,000 cases of Norwalk-like virus infections occur annually in the United States. When these viruses are recognized, it is usually because they are associated with an outbreak of gastrointestinal illness. Standard hospital laboratories and commercial laboratories usually are not equipped to detect Norwalklike viruses. The specialized laboratories that can detect these viruses perform tests on stool specimens and, in some cases, can identify evidence of infection by testing blood for antibody. Research trials on a Norwalk virus plant-based vaccine being conducted at several universities in the U.S. show initial success, with participants developing an immune response to the vaccine. Stay tuned. Rabies in Washington State In November, the first case of terrestrial animal rabies since 1994 in Washington State was confirmed at the State Public Health Laboratories and the Centers for Disease Control and Prevention (CDC). The affected animal, an unvaccinated cat from Walla Walla county, may have been exposed to a rabid bat; further testing is being conducted at the CDC. This case emphasizes the importance of vaccinating pets and taking appropriate precautions when humans are potentially exposed to rabies, including reporting bites to SRHD. Each case is investigated by SRHD staff in collaboration with Animal Control, with the dual purposes of 1) location and confinement or testing of the animal and 2) evaluation of the exposure risk of the victim. If an animal under observation for 10 days shows no sign of disease, postexposure prophylaxis (PEP) is generally not recommended. If a decision has been made to euthanize the animal, it can be tested quickly for the presence of the rabies virus if the head has been properly preserved. In most cases, observation and/or testing can prevent costly and lengthy PEP. PEP is effective if administered within 14 days of the bite incident, so there is no urgency to begin the series before the results of the testing or the observation period is complete. Rabies in Washington is almost invariably transmitted by rabid bats. The last rabid animal that was not a bat was a llama, infected in 1994 in King County, through the bite of an infected bat. The last rabid cat occurred in Thurston County, in 1976, and was presumably infected by a bat. (Testing at the time was not sophisticated enough to determine the strain of the rabies virus.) The last human case of rabies occurred in 1996, following infection with bat strain rabies in a 64 year old Mason county man. He lived in a rural area, and had recently cleaned out a shed, but the family was not aware of any specific exposure to bats. In the Walla Walla case, members of the family who owned the cat and were scratched, bitten, or exposed to the cat's saliva received PEP to prevent rabies, as did a neighbor and several staff in a veterinary clinic where the cat was taken after becoming ill. The family also owns two dogs that have not been recently vaccinated against rabies. The dogs are quarantined for six months because of the risk that they may have been exposed to the rabid cat. Rabies control in animals relies on the routine vaccination of animals for which vaccine is available. Rabies immunization should be current for all domestic dogs, cat and ferrets. Vaccine efficacy in captured wild animals or hybrids (pet raccoons, skunks, wolf-dog) is unknown, and keeping these animals is not recommended. Dogs, cats or ferrets that bite humans should be observed for 10 days or euthanized and examined for rabies. Cases of Selected Diseases Reported to Spokane Regional Health District—Jan 2002 DISEASE AIDS *Cumulative – 405 (as of Dec 2001) THIS MONTH (January 2002) ** LAST MONTH (Dec 2001) **1 LAST YEAR TO DATE (Dec 2001) **22 THIS YEAR TO DATE (January 2002) ** Borreliosis (Relapsing Fever) 0 0 0 0 Campylobacteriosis 4 4 9 41 4 48 60 720 48 Chlamydial STD Enterohemorrhagic E Coli (including 0157:H7) 1 0 9 12 1 Giardiasis 3 5 9 63 3 Gonorrhea 16 9 94 16 Hepatitis A acute 2 0 3 2 Hepatitis B acute 3 4 34 3 Hepatitis B chronic Hepatitis C acute and chronic HIV *Cumulative – 101 (as of Dec 2001) Influenza (Sep 1 – Aug 31) 9 3 62 9 74 42 799 74 NA NA NA NA 3 0 0 3 Measles (Rubeola, Red) 0 0 0 0 Meningococcal Disease 0 0 7 0 Mumps 0 0 0 0 Pertussis (Whooping Cough) 0 0 1 0 Rubella (German Measles) 0 0 0 0 Salmonellosis 2 10 9 43 2 Shigellosis 0 0 6 0 Syphilis 0 0 3 0 **0 **0 **11 **counts generated by State DOH are one month delayed 9 includes case reports for previous months to correct year-end totals **0 Tuberculosis** (as of Nov 2001)