Download III BSC BT - 609 A -core- Animal Biotechnology

Dr.G.R.Damodaran College of Science
(Autonomous, affiliated to the Bharathiar University, recognized by the UGC)Re-accredited at
the 'A' Grade Level by the NAAC and ISO 9001:2008 Certified
CRISL rated 'A' (TN) for MBA and MIB Programmes
III BSc [2014-2017]
Semester VI
Core: ANIMAL BIOTECHNOLOGY - 609 A
Multiple Choice Questions.
1. ________ process that directly manipulates an organism's DNA and genetic fate.
A. Meiosis.
B. Genetic engineering.
C. DNA isolation.
D. Mitosis.
ANSWER: B
2. Which carries a DNA sequence into a host?
A. Plasmid.
B. tRNA.
C. mRNA.
D. Vector.
ANSWER: D
3. Each individual human sperm and unfertilised egg contain _____________ .
A. The full set of 23 paired chromosomes.
B. 23 individual (unpaired) chromosomes.
C. Different things (sperm contains chromosomes and the egg contains DNA).
D. Both X and Y chromosomes.
ANSWER: B
4. The injectable polio vaccine developed by ____________ was one of the first products mass-produced using cell
culture techniques.
A. Edward Jenner.
B. Joseph Lister.
C. Jonas Salk.
D. Fredric Sanger.
ANSWER: C
5. The most commonest indicator in animal cell culture medium is ___________.
A. Rose bengal.
B. Bromocresol purple.
C. Phenol red.
D. Crimson orange.
ANSWER: C
6. The appropriate pH required to maintain the cell line is _____________.
A. 7.0 - 7.5.
B. 7.5 - 7.7.
C. 7.0 - 8.0.
D. 7.2 - 7.5.
ANSWER: D
7. The most common sugar source for animal cell line is _____________.
A. arabinose.
B. sucrose.
C. maltose.
D. arabinose.
ANSWER: D
8. Embryonic stem cells are derived from the __________ cell masses of normal blastocysts.
A. inner.
B. outer.
C. peripheral.
D. anterior
ANSWER: A
9. A fertilized ovum is known as __________ .
A. zygote.
B. dycote.
C. unigote.
D. oogote.
ANSWER: A
10. In transgenesis, the foreign gene is known as _________ gene .
A. mutated.
B. additional.
C. trans.
D. true.
ANSWER: C
11. Lothar Hennighausen group was able to produce a pig expressing large quantities of __________ .
A. Whey acidic protein (WAP).
B. tertiary structures of protein.
C. growth factors.
D. attachment factors.
ANSWER: A
12. The Worlds first transgenic primate is known as _______ .
A. UTDi.
B. GENi.
C. CLONi.
D. ANDi.
ANSWER: D
13. The oncomouse is also known as ________mouse .
A. Pheladelphia.
B. Ohio.
C. Smart.
D. Harvard.
ANSWER: D
14. Gene targeting in mouse embryonic stem cells has become the gold standard for determinination of gene
_________ in mammals.
A. function.
B. structure
C. analysis
D. group.
ANSWER: A
15. Gene therapy is a technique for __________ the defective genes responsible for disease development.
A. altering.
B. replacing.
C. correcting.
D. analysing.
ANSWER: C
16. In gene therapy, the abnormal gene could be repaired through selective ___________, that returns the gene to its
normal function.
A. alteration.
B. reverse mutation.
C. removal.
D. retrival.
ANSWER: B
17. Restriction enzymes can be used to _____________ .
A. join up bits of dna.
B. inhibit the activity of transfer RNA.
C. 'snip' DNA with great precision at certain known base sequences.
D. stop the transcription of DNA into messenger RNA.
ANSWER: C
18. Transgenic mice lacking the gene for a dopamine re-uptake pump (Giros et al 1996) have been shown to
_____________ .
A. produce more dopamine.
B. be behaviourally less active.
C. be very sensitive to the effects of alcohol.
D. be insensitive to the effects of amphetamine and cocaine.
ANSWER: D
19. Mice that have had the gene for the serotonergic 5-HT1B 'knocked out' _____________ .
A. drink twice as much alcohol as normal.
B. are very sensitive to the effects of alcohol.
C. become hyperactive after ingesting alcohol.
D. are less aggressive.
ANSWER: A
20. Prokaryotic cellular contents are enclosed in a__________ and then surrounded by a__________ .
A. capsule, cell wall.
B. cytoplasm, cell wall.
C. plasma membrane, cell wall.
D. cell membrane, capsule.
ANSWER: C
21. Contraceptive pills checks _____________ .
A. implantation.
B. entry of sperms in vagina. .
C. ovulation.
D. fertilization.
ANSWER: C
22. Eggs in mammals are _____________ .
A. alecithal
B. microlecithal.
C. mesolecithal.
D. macrolecitha
ANSWER: A
23. In __________ month foetus survive outside the uterus.
A. sixth.
B. fourth.
C. seventh.
D. eighth.
ANSWER: C
24. Tiny cells, which are separated at time of maturation from developing ovum, are called ______.
A. Polar
B. Primary oogonia.
C. Secondary oogonia.
D. Primary spermatogonia.
ANSWER: A
25. Xenotransplantation in animals involves in the production of _____________ . .
A. organs.
B. proteins.
C. biosurfactants.
D. all the above
ANSWER: A
26. Mammalian cells take up recombinant DNA directly when treated with _________ ions.
A. calcium.
B. potassium.
C. vanadium.
D. magnesium.
ANSWER: A
27. Gene knock-out means __________ of specific gene.
A. inactivating.
B. removal.
C. purification.
D. all the above
ANSWER: A
28. Sperm pass through all of the following structures EXCEPT the _____________ .
A. urinary bladder.
B. ejaculatory duct.
C. urethra.
D. ductus deferens.
ANSWER: A
29. Infertility is the inability to conceive a child after __________ year(s) of frequent intercourse without the use of
contraceptives.
A. 1.
B. 2.
C. 3.
D. 5.
ANSWER: C
30. Lack of sperm in men is called___________.
A. mesosperma.
B. oligospermia.
C. azoospermia.
D. spermia.
ANSWER: C
31. The alleles in a population constitute the _____________ .
A. chromosome complement.
B. karyotype.
C. gene pool.
D. allele group.
ANSWER: B
32. Which of the following genetic disorders is NOT thought to be Mendelian?
A. Cystic fibrosis.
B. Tay-Sachs disease.
C. Hemophilia.
D. Hypertension.
ANSWER: D
33. A human female has _________ pairs of autosomes and ________ of the sex chromosome complement.
A. 23, XX.
B. 23, X.
C. 22, XX.
D. 22, XY.
ANSWER: C
34. In humans, an individual with an XXY chromosomal complement will develop as ____________ .
A. a Male.
B. an hermaphrodite.
C. a female.
D. super-female.
ANSWER: A
35. Which are called Sperm mother cells ____________
A. Spermtids
B. Spermatogonia
C. Spermatocytes
D. Primordial germ cells
ANSWER: B
36. HeLa cell lines are derived from _________ cancer cells.
A. cervical.
B. lung.
C. blood.
D. liver.
ANSWER: A
37. Trypsin is a _____________ enzyme.
A. amylolytic.
B. amylolytic.
C. Proteolytic.
D. Cellulolytic.
ANSWER: C
38. _________ is a effective cryoprotectant.
A. amyl
B. DMSO.
C. trypsin.
D. liquid nitrogen.
ANSWER: B
39. The term grey crescent is associated with the egg of _____________ .
A. branchiostoma and frog
B. frog.
C. chick.
D. frog and chick.
ANSWER: D
40. From a primary Oocyte ________________
A. One egg is produced
B. 3 eggs are produced
C. 4 eggs are produced
D. 2 eggs are produced
ANSWER: A
41. In which stage of development does a zygote go through the structural and functional specialization of groups of
cells?
A. Growth.
B. Differentiation.
C. Morphogenesis.
D. Fertilization.
ANSWER: A
42. Which gene transfer technique involves a tiny needle which is used to inject DNA into a cell lacking that DNA
sequence?
A. Electroporation.
B. Microinjection.
C. Liposome transfer.
D. Particle bombardment
ANSWER: B
43. The introduction of a gene into a cell where it exchanges places with its counterpart in the host cell is called
__________.
A. transgenic technology.
B. gene targeting.
C. knockout technology.
D. recombinant DNA technology.
ANSWER: B
44. A multicellular organism that carries a specific genetic change in each cell because of an intervention at the
fertilized egg stage is a _____________ .
A. transversion.
B. transition.
C. transgenic.
D. transformant.
ANSWER: C
45. The life span of the sperm is _________.
A. 2 days.
B. 1-3 days.
C. 1-3weeks
D. 7 days.
ANSWER: B
46. Vectors are _____.
A. molecules that degrade nucleic acids.
B. molecules that are able to covalently bond to and carry foreign dna into cells.
C. molecules that protect host cells from invasion by foreign DNA.
D. DNA regulators.
ANSWER: B
47. Which of the following vector can maintain the largest fragment of foreign DNA?
A. YAC.
B. Cosmid.
C. Plasmid.
D. Plastid.
ANSWER: A
48. Animal that has gained new genetic information from the acquisition of foreign DNA is a __________ .
A. chimera.
B. transgenic animal.
C. vector.
D. transferred animal.
ANSWER: B
49. Most current gene therapy trials target _____________ .
A. SCID deficiency.
B. cancer.
C. cystic fibrosis.
D. HIV.
ANSWER: B
50. Extranuclear genetic material is found in _________.
A. plastid and nucleus.
B. mitochondria and plastids.
C. nucleus and cytoplasm.
D. mitochondria and nucleus.
ANSWER: B
51. Which of the following is not true of viruses?
A. they are obligate intracellular parasites
B. a specific virus will only infect a specific cell type
C. they can mutate
D. All of the choices characterize viruses.
ANSWER: D
52. Dolly sheep was genetically similar to ________ .
A. the mother from which nucleated fertilized egg was taken.
B. the mother from which nuclear dna of udder cell was taken.
C. the surrogate mother.
D. both surrogate mother and nuclear donor mother.
ANSWER: B
53. The complete set of chromosomal and extrachromosomal genes of an organisms is called ________ .
A. genome.
B. gene pool.
C. gene bank.
D. gene library.
ANSWER: A
54. Which of the following is used in forensic science?
A. Bacterial cloning.
B. DNA foot printing.
C. DNA fingerprinting.
D. DNA cloning.
ANSWER: C
55. Genetically engineered bacteria are being used in commercial production of _______.
A. melatonin.
B. testoteron.
C. human insuline.
D. thyroxine.
ANSWER: C
56. Introduction of foreign genes for improving genotype is ________ .
A. tissue culture.
B. immunisation.
C. biotechnology.
D. genetic engineering.
ANSWER: D
57. Most abundant RNA of the cell is ___________ .
A. tRNA.
B. rRNA.
C. mRNA.
D. tRNA.
ANSWER: B
58. A totipotent cell means ______________
A. An undifferentiated cell capable of developing into a system
B. An undifferentiated cell capable of developing into an organ
C. ) An undifferentiated cell capable of developing into complete embryo
D. Cell which lacks the capability differentiate into an organ
ANSWER: A
59. DNA replication takes place during _________phase.
A. S.
B. G2.
C. G1.
D. M.
ANSWER: A
60. Sertoli cells are otherwise called _____________
A. Plasma cells
B. Nurse cells
C. Germinal cells
D. Parietal cells
ANSWER: B
61. Which of the following is an example of cell devoid of nuclear membrane and mitochondria ?.
A. Bacterial cell.
B. Sperm.
C. Protist.
D. Sponge cell.
ANSWER: A
62. Animal cell differs from plant cells in possessing __________ .
A. plastid.
B. golgi body.
C. vacuole.
D. centrosome.
ANSWER: A
63. Longest cells in human body is _______ cells.
A. leg muscle.
B. bone.
C. nerve.
D. heart muscle.
ANSWER: C
64. The suffix 'S' in ribosome unit indicates _____________ .
A. solubility.
B. surface area.
C. sedimentation coefficient.
D. size.
ANSWER: C
65. A change in the amount of yolk and its distribution in the egg will affect ________.
A. fertilization.
B. formation of zygote.
C. pattern of cleavage.
D. number of blastomeres produced.
ANSWER: C
66. Type of cleavage found in mammals is
A. Holoblastic
B. Meroblastic
C. Superficial
D. None of the above
ANSWER: A
67. Connective tissue around seminiferous tubules possess endocrine cells called ________ .
A. leydig cells.
B. sertoli cells.
C. sertoli cells.
D. both a and b.
ANSWER: A
68. Conversion of spermatids into sperms is ___________ .
A. spermiogenesis.
B. spermatogenesis.
C. gametogenesis.
D. metamorphosis
ANSWER: A
69. Corpus luteum develops under the influence of ____________ .
A. estrogen.
B. estrogen.
C. follicle stimulating hormone.
D. leltinising hormone
ANSWER: D
70. Correct sequence of hormone secretion from beginning of menstruation is __________ .
A. FSH, progesterone, estrogen.
B. Estrogen, FSH, progesterone.
C. FSH, estrogen progesterone.
D. Estrogen, progesterone, FSH.
ANSWER: C
71. Immediately after ovulation, the mammalian egg is covered by a membrane known as _____.
A. chorion.
B. zona pellucida.
C. corona radiata.
D. vitelline membrane.
ANSWER: B
72. Each centriole in the mature sperm consist of _______________
A. 2 central and 9 peripheral fibrils
B. 3 central and 6 peripheral fibils
C. 4 central and 5 peripheral fibrils
D. 9 central and 2 peripheral fibrils
ANSWER: A
73. Unfertilized egg of human, when released from ovary, contains _________chromosome.
A. one Y.
B. ageing.
C. menopause.
D. one X
ANSWER: D
74. Preserving germplasm in frozen state is ______________
A. Cryopreservation
B. Cold storage
C. In situ preservation
D. Vernalisation
ANSWER: A
75. Capacitation of sperm occurs in _____________ .
A. vagina.
B. female genital tract.
C. vas efferens.
D. male genetal tract
ANSWER: A
76. What is the inner lining of the uterus?
A. cervix.
B. female genital tract.
C. vas efferens.
D. Endometrium
ANSWER: D
77. Brain / CNS develops from _____________ .
A. ectoderm.
B. mesoderm.
C. endoderm.
D. ectoendoderm.
ANSWER: A
78. Where does fertilization usually take place?
A. cervix.
B. vagina.
C. uterus.
D. oviduct.
ANSWER: D
79. The process of sperm production takes place in the _____________ .
A. epididymis.
B. vas deferens.
C. prostate glands.
D. seminiferous tubules.
ANSWER: D
80. Which one of the followings secretes the gonadotropic hormones?
A. Adrenal.
B. Anterior pituitary.
C. Posterior pituitary.
D. Thyroid.
ANSWER: B
81. Introduction of foreign genes for improving genotype is ______________
A. Tissue culture
B. Immunisation
C. Biotechnology
D. Genetic engineering
ANSWER: D
82. Where do the female gonads (paired ovaries) lie?
A. Pelvic cavity.
B. Thoracic cavity.
C. abdominal
D. Scrotal sacs.
ANSWER: A
83. Which one of the following statements about human sperm is correct?
A. Acrosome serves no particular function.
B. The sperm lysins in the acrosome dissolve the egg envelope facilitating fertilization.
C. Acrosome has a conical pointed structure used for piercing and penetrating the egg resulting in fertilization.
D. Acrosome serves as a sensory structure leading the sperm towards the ovum.
ANSWER: C
84. What is the correct surgical method for preventing pregnancy in which the vas deferens is cut?
A. Ovariectomy.
B. Hysterectomy.
C. Vasectomy.
D. Castration.
ANSWER: C
85. In ______ the egg is first fertilized outside the body and then it is inserted into the oviduct.
A. gamete intrafallopian transfer.
B. zygote intrafallopian transfer.
C. intracytoplasmic sperm injection.
D. in vitro fertilization.
ANSWER: D
86. GIFT (Gamete Intra Fallopian Transfer) mixes egg and sperm in the _____________ .
A. fallopian tube.
B. uterus.
C. vagina.
D. culture medium.
ANSWER: A
87. The highly sophisticated procedure of directly injecting a sperm into an egg is called _________ .
A. intracytoplasmic sperm injection.
B. zygote intrafallopian transfer.
C. gamete intrafallopian transfer.
D. AID.
ANSWER: A
88. The technique called gamete intrafallopian transfer (GIFT) is recommended for those females _____________ .
A. whose cervical canal is too narrow to allow passage for the sperms.
B. who cannot provide suitable environment for fertilisation.
C. who cannot produce an ovum.
D. who cannot retain the foetus inside uterus.
ANSWER: C
89. in vitro fertilisation is a technique that involves transfer of which one of the following into the fallopian tube?
A. Zygote only.
B. Embryo only, up to 8 cell stage.
C. Either zygote or early embryo up to 8 cell stage.
D. Embryo of 32 cell stage.
ANSWER: C
90. Cu ions released from copper-releasing Intra Uterine Devices (IUDs) ____________ .
A. prevent ovulation.
B. make uterus unsuitable for implantation.
C. increase phagocytosis sperms.
D. suppress sperm motility.
ANSWER: D
91. Which statement is NOT true about a retrovirus?
A. It may cause cancer or AIDS.
B. It contains reverse transcriptase
C. It is known to cause diseases only in animals, not in humans.
D. It has the capacity to integrate cDNA into the host DNA of the cell it infects.
ANSWER: C
92. Blood cells that transport oxygen within the body are the _____________ .
A. plasma.
B. erythrocytes.
C. platelets.
D. leukocytes.
ANSWER: B
93. Cancer cells are more easily damaged by radiation than normal cells because they ___________ .
A. starved of nutrition.
B. different in structure.
C. non dividing.
D. undergo rapid division.
ANSWER: D
94. Chemically an antibody is _____________ .
A. nucleoprotein.
B. lipid.
C. carbohydrate.
D. protein.
ANSWER: D
95. Best method to determine paternity is ________________
A. Protein analysis
B. Chromosome counting
C. Gene counting
D. DNA finger printing
ANSWER: D
96. Which glands secrete hormones directly into the extracellular space?
A. Endocrine.
B. Apocrine.
C. Merocrine
D. None of the above.
ANSWER: A
97. Which of the following has slowest growth rate?
A. Connective tissue.
B. Epithelial
C. Nervous tissue.
D. none of them.
ANSWER: C
98. Epithelial tissues arise from _____________ .
A. ectoderm.
B. endoderm.
C. mesoderm
D. all the above.
ANSWER: D
99. Functional unit of kidney is _____________ .
A. glomerulus.
B. henleys loop.
C. nephron.
D. pelvis.
ANSWER: C
100. The junction of two neurons is called _____________ .
A. synapse.
B. relay.
C. synapsis.
D. conduction zone.
ANSWER: A
101. Bioethcs is related to ________________
A. Preventing biopiracy
B. Regulation of unethical activities likegene cloning in animals
C. Preventing theft of living materials
D. Moral guidance to the problems in biology
ANSWER: B
102. Pasteur chose the Latin root word for "virus" meaning ____________ Answer: C
A. extremely small.
B. non-living.
C. poison.
D. particle.
ANSWER: C
103. Which of the following could be used to grow viruses in the laboratory?
A. chicken eggs
B. bacteria
C. white blood cells
D. All of the choices could be used
ANSWER: D
104. Which of these diseases could NOT be treated with antibiotics?
A. Chlamydia
B. plague
C. influenza
D. scarlet fever
ANSWER: C
105. Selective breeding of organisms (Animal husbandry and plant breeding programs) for specific desirable
characteristics are examples of _____________ .
A. mutation.
B. reverse evolution.
C. artificial selection.
D. natural selection.
ANSWER: C
106. Gestation period in human is ___________ weeks.
A. 10
B. 28.
C. 32.
D. 38.
ANSWER: D
107. Fertilization is the union of _____________ .
A. diploid spermatozoon with diploid ovum to form diploid zygote.
B. haploid sperm with haploid ovum to form haploid zygote.
C. haploid sperm with haploid ovum to form diploid zygote.
D. diploid sperm with haploid ovum to form triploid zygote.
ANSWER: C
108. Estrogen level is maximum in which part of ovarian cycle _________ phase.
A. secretory.
B. ovulatory.
C. proliferative.
D. menstrual.
ANSWER: C
109. A transgenic mouse is an example of _________ gene therapy.
A. germline.
B. heritable.
C. constitutional.
D. somatic.
ANSWER: A
110. Genetic engineering manipulates gene products at the level of the _____________ .
A. protein.
B. amino acid.
C. DNA.
D. RNA.
ANSWER: C
111. A knockout mouse is so named because _____________ .
A. it contains aggression genes.
B. it contains multiple copies of a human gene.
C. it contains an activated human gene.
D. none of the above.
ANSWER: C
112. The first patent for a transgenic organism was awarded in 1988. Which organism was patented?
A. A yeast used in industrial processes.
B. A bacterium able to metabolize components of crude oil.
C. A mouse that manufactures human protein in its milk.
D. Life forms cannot be patented.
ANSWER: C
113. Gene targeting is done on a(n) _____________ .
A. sperm cell.
B. egg cell.
C. fertilized ovum.
D. early embryonic cell.
ANSWER: D
114. Recombinant DNA technology methods began in the _____________ .
A. 1950's.
B. 1960's.
C. 1970's.
D. 1980's.
ANSWER: C
115. ____________ are used to select genes of interest from a genomic library.
A. Restriction enzymes.
B. Cloning vectors.
C. DNA probes.
D. Gene targets.
ANSWER: C
116. DNA will precipitate out of solution in a test tube of lysed cells when ______ is added.
A. ethanol.
B. water.
C. acetone.
D. acetic acid.
ANSWER: A
117. What carries a DNA sequence into a host?
A. Plasmid.
B. tRNA.
C. mRNA.
D. Vector.
ANSWER: D
118. DNA does not occur in _______________
A. Nucleus
B. Ribosomes
C. Mitochodria
D. Plastids
ANSWER: B
119. The probability that a child in a particular family will inherit a recessive disorder is 1/4. If the parents have three
normal children, what is the probability that their fourth child will inherit the disorder?
A. 0.
B. ¼.
C. ½.
D. 1.
ANSWER: B
120. A________specimen is made by adding a dye to color only certain structures of a cell. .
A. wet mount.
B. cultured
C. highlighted.
D. stained
ANSWER: D
121. If a virus is termed latent this means it ____________
A. cannot be a retrovirus.
B. has not entered a lytic cycle.
C. has not entered a lysogenic cycle.
D. is gaining a new envelope via "budding.''
ANSWER: B
122. In the male reproductive systems, the _______ collects and stores maturing sperm cells.
A. urethra.
B. seminal vesicles.
C. testes.
D. epididymis.
ANSWER: D
123. In the female reproductive system, the mature egg travels from the ovary through the _______ to the uterus.
A. ducts.
B. oviducts.
C. endoducts.
D. vas deferns.
ANSWER: B
124. Genetically engineered bacteria are being used in commercial production of ____________
A. Melatonin
B. Testoteron
C. Human insuline
D. Thyroxine
ANSWER: C
125. Sertoli cells are located in __________.
A. cauda epididymis.
B. seminiferous tubules.
C. germinal epithelium.
D. caput epididymis.
ANSWER: B
126. If seminiferous tubules are cut and removed then __________.
A. spermatogenesis will not occur.
B. spermatogenesis will not be non nucleated
C. sperms in semen will be non-motile.
D. sperms will not be in semen.
ANSWER: D
127. Which of the following is NOT a primary germ layer?
A. Ectoderm.
B. Endoderm.
C. Endoderm.
D. Mesoderm.
ANSWER: D
128. What is the unique thing about stem cells that makes them so desirable for therapeutic use?
A. They are found in reproductive tissue.
B. They develop into nerve cells and can be used by stroke victims.
C. They develop into organs needed for transplant.
D. They can develop into many different tissue types.
ANSWER: D
129. Binary fission is seen in ________.
A. plasmodium.
B. hydra.
C. amoeba
D. mucor.
ANSWER: A
130. Which of the following cell types can be produced by stem cells?
A. Placental.
B. Neuronal.
C. RBC.
D. Both neuronal and RBC.
ANSWER: D
131. Human embryonic stem cells are derived from ____________.
A. morula.
B. egg.
C. inner cell mass.
D. trophoblast.
ANSWER: C
132. Recombinant DNA technology methods began in the __________.
A. 1950's.
B. 1960's.
C. 1970's.
D. 1980's.
ANSWER: C
133. _______ are used to select genes of interest from a genomic library.
A. restriction enzymes.
B. cloning vectors.
C. DNA probes.
D. gene targets.
ANSWER: C
134. For the same gene, it is possible to patent __________.
A. expressed sequence tags.
B. cDNA.
C. SNPs.
D. all of the above.
ANSWER: D
135. The cDNA version of a gene includes _________.
A. codons for a mature mrna.
B. sequences corresponding to promoters.
C. sequences corresponding to introns.
D. both b and c.
ANSWER: A
136. Which of the following transgenic pharming products is incorrectly paired with the host organism that produces
it?
A. hemoglobin rabbit.
B. human growth hormone rat.
C. lactoferrin cows.
D. alpha1antitrypsinsheep.
ANSWER: A
137. Two organisms mate. One is heterozygous for tallness (Tt) and the other is homozygous recessive (tt). What are
the possible phenotypic outcomes for this mating?
A. 4 tall offspring.
B. 3 tall offspring, 1 dwarf.
C. 2 tall offspring, 2 dwarf.
D. 4 dwarves.
ANSWER: C
138. Palindromic sequences in DNA __________.
A. a. form "blunt" ends when cut by restriction enzymes.
B. reflect the same sequence on two sides.
C. are not useful in recombinant dna experiments.
D. both a and b.
ANSWER: A
139. Which of the tools below is used to cut the gene from its normal location?
A. Restriction enzyme.
B. Plasmid.
C. Bacteriophage.
D. Vector.
ANSWER: A
140. Acrosomal enzymes in a mammalian sperm originate from ____________.
A. peroxisomes.
B. lysosomes.
C. microsomes.
D. mitochondria.
ANSWER: C
141. Human insulin is being commercially produced from a transgenic species of ___________________
A. Saccharomyces sp.
B. Escherichia sp.
C. Mycobacterium sp.
D. Rhizobium sp.
ANSWER: B
142. Animal cell culture was first successfully undertaken by ___________.
A. Freshney.
B. Robert Koch.
C. John a. Ryan.
D. Ross Harrison.
ANSWER: D
143. Nuclear gene expression can be regulated by histone __________.
A. methylation.
B. acetylation..
C. remodelling.
D. re-arrangement.
ANSWER: B
144. The phrase "one gene-one enzyme" is associated with the work of __________.
A. Lederberg.
B. Watson and Crick.
C. Beadle and Tatum.
D. Mendel.
ANSWER: C
145. What is the 'acrosomal reaction'?
A. The acrosomal reaction is a repulsive interaction between the sperm and the egg.
B. The acrosomal reaction is the digestion of the acrosome by the sperm when it encounters an egg.
C. The acrosomal reaction is the digestion of the zona pellucida, permitting the sperm to contact the egg.
D. The acrosomal reaction is the fusion of the sperm and egg plasma membranes.
ANSWER: C
146. Basically, what does the frequency of a plant tell us?
A. The number of individuals that are in the community.
B. The importance of the species to the community.
C. The amount of area the species covers in the community.
D. The number of times the species is encountered in the community.
ANSWER: D
147. Most current gene therapy trials mainly targets on______.
A. SCID deficiency.
B. cancer.
C. cystic fibrosis.
D. HIV.
ANSWER: B
148. Which one of the following human cells do not contain mitochondria?
A. nerve cell.
B. red blood cell.
C. liver cell.
D. white blood cell.
ANSWER: B
149. When was the first gene therapy patient treated?
A. 1988.
B. 1990.
C. 1993.
D. 1999.
ANSWER: B
150. The plasmid of E. coli coded for ________.
A. ampicillin production.
B. ampicillin resistance.
C. DNA production.
D. saline resistance.
ANSWER: B
Staff Name
Dr. BALAMBIGAI N .