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3 Energy Pathways Sources of fuel for the body • Fat (mainly used for low/mod activity) • Carbohydrate (mainly used for mod/high activity) • Protein – used for fuel in extreme situations like starvation. All fuels are broken down to produce ATP. When ATP is split energy is released. ATP • Adenosine tri-phosphate A P P P • When one of the phosphate bonds is broken, ATP becomes ADP a phosphate is freed up and energy released. A P P P Energy Energy Pathways ATP-PC pathway - for rapid regeneration of ATP. Phospho-creatine can anaerobically donate a phosphate to ADP to form ATP during the first 2 to 7 seconds following an intense muscular effort. PC stores in the muscle are exhausted within 8-10 seconds of maximal effort. It takes almost 5 mins for phospho-creatine stores to be replenished so rest intervals between maximal sprints or max. lifts need to reflect this. Anaerobic System Anaerobic glycolysis occurs in the cytoplasm of the cell in the absence of oxygen. Using this pathway, ATP is produced from breaking down glycogen which is the stored form of glucose in the muscle. Glucose is the body’s preferred source of fuel for sports activities. Exercise Intensity? • During intense exercise, oxygen supply cannot meet demand therefore the muscle tissue respires anaerobically to produce energy. • A by-product of anaerobic glycolysis is lactic acid which accumulates quickly during intense exercise causing short term muscle fatigue e.g. resistance training at 80%+ of your maximum. Anaerobic Glycolysis (only extracts 5% of energy available in the glucose molecule). glucose glucose 6- phosphate 2 ATP pyruvic acid lactic acid This process takes place in the absence of O2 in the cytoplasm of the cell. Aerobic Pathway (extracts the remaining 95% of energy available in the glucose molecule in the presence of oxygen). Pyruvic acid This process takes place in the mitochondrion of the cell Acetyl Co-enzyme A Citric Acid CO2 Krebs Cycle 2 ATP H+ e- Electron Transfer Chain Final stages of aerobic respiration… • Here glucose is downgraded to release hydrogen and carbon dioxide. The CO2 is eliminated via the lungs. • The hydrogen given off at krebs cycle is brought by hydrogen carriers NAD & FAD to the cristae of the mitochondrion. Here it is split into hydrogen ions (H+) and electrons (e-). Electron Transfer Chain • The hydrogen ions combine with oxygen to form water which is used in various ways by the body. • The hydrogen electrons cascade through multiple reactions in the electron transfer system to release 34 ATP. • Total energy released by one glucose molecule is 38ATP (2 ATP during anaerobic glycolysis, 2 ATP during krebs cycle and 34 ATP during the electron transfer chain). Revision Questions • What are the three main sources of fuel for the body? • What happens when ATP is split? • Describe the ATP-CP energy pathway. • Describe the stages in anaerobic glycolysis. • Describe the stages of aerobic respiration. • How much ATP is produced in the downgrading of one glucose molecule?