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Transcript
Immuno-Quiz
20.07.2016
Cytokines and chemokines
What are cytokines?
Cytokines and chemokines
Which are the three structural main
families of the cytokines?
Please give one example for each case.
Cytokines and chemokines
How do the cytokines act?
(characterize their properties to
interact)
Cytokines and chemokines
Mention four general immunological
processes in which cytokines are
involved.
Complement system
Explain the three ways which lead to the
activation of the complement systems.
Complement system
Name the three main tasks of the
complement system.
Complement system
What is the function of the complement
protein C5b?
Complement system
Point out the functions of the small
complement proteins C3a, C4a and
C5a?
B-cells and antibodies
What are immunoglobulins and how is
their basic structure?
B-cells and antibodies
Which antibody classes (isotypes) are
classified and where do they mostly
occur?
B-cells and antibodies
Explain the terms affinity and avidity?
Antigen presentation
Which cells are involved in the antigen
presentation?
Antigen presentation
Which signals are needed for the
activation of T-cells?
Innate immunity
How does LPS affect macrophages?
Describe the signalling cascade!
Cytokines and chemokines
Mention four general immunological
processes in which cytokines are
involved.
B-cells and antibodies
How and where does the B-cell
maturation take place?
T-cells
How does the T-cell-mediated immunity
take place?
Innate immunity
What are PAMPs and PRRs?
Name one example each!
Innate immunity
Name the humoral and cellular
factors of the innate immunity.
Group: T-cells
Cytokines and chemokines
Name at least four cytokines, which are
secreted by activated macrophages.
Antigen presentation
Why is antigen presentation necessary?
Antigen presentation
How large are the bound peptide
fragments which can bind MHC-I or
MHC-II?
Innate immunity
Describe differences between
innate immunity and acquired
immunity.
Cytokines and chemokines
What are pleiotropic cytokines?
Name one example.
B-cells and antibodies
Describe the differences between the
various immunoglobulins.
Antigen presentation
Which MHC-complexes activate which
T-cells?
Cytokines and chemokines
During cell contact with endotoxins a
signalling cascade is triggered, leading
to the release of cytokines.
On which receptor binds thereby the
LPS-LBP-CD14-complex?
Innate immunity
Describe the advantages of the innate
immune response
B-cells and antibodies
What is described as
„Immunoglobulin-superfamily“?
Antigen presentation
How differ MHC I- and MHC IImolecules?
Antigen presentation
What is the purpose of the invariant
chain and the CLIP-protein on the MHCII-molecules in the ER?
T-cells
Which maturation phases exist for
the T-cells and where does the
maturation take place?
T-cells
What kind of T-cells are present in the
organism?
B-Zellen und Antikörper
What is the difference between
neutralisation and opsonisation?