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Transcript
Exploring Mendelian
Genetics
Two trait Crosses
11.3
Dihybrid crosses
•All of the crosses discussed
so far have involved only a
single trait.
•Ex. Tt
•However, Mendel also
conducted crosses that
examine the inheritance of two
different traits.
•He wondered if both traits
would always appear together
or if they would be expresses
independently of each other.
Two-Factor Cross
• Mendel crossed pure-breeding
plants for two traits
– Round, Yellow x wrinkled, green
– RRYY x rryy
• All F1 offspring produced were
Round, Yellow
– Yellow is dominant to Green
– Round is dominant to wrinkled
• Genotype of F1 offspring is RrYy
• Mendel’s dihybrid
crosses with
heterozygous plants ( F1
generation) yielded a
9:3:3:1 phenotypic ratio
for the F2 generation.
• Mendel’s dihybrid
crosses led to his second
law,
the law of independent
assortment.
A dihybrid cross
involves two traits.
• The law of independent
assortment states that allele
pairs separate independently of
each other during meiosis.
• Independent assortment helps
account for the many genetic
variations observed in plants,
animals, and other organisms.
Dihybrid Cross
RrYy x RrYy
RY
RY
Ry
rY
ry
Ry
rY
ry
Dihybrid Cross
RY
Ry
rY
ry
RY RRYY
RRYy
RrYY
RrYy
Ry RRYy
RRyy
RrYy
Rryy
rY RrYY
RrYy
rrYY
rrYy
RrYy
Rryy
rrYy
rryy
ry
Genotype Ratio
RRYY-1/16
RRYy-2/16
RRyy- 1/16
RrYY- 2/16
RrYy- 4/16
Rryy- 2/16
rrYY- 1/16
rrYy- 2/16
rryy- 1/16
Dihybrid Cross
RY
Ry
rY
ry
RY RRYY
RRYy
RrYY
RrYy
Ry RRYy
RRyy
RrYy
Rryy
rY RrYY
RrYy
rrYY
rrYy
wrinkled/Yellow: 3
RrYy
Rryy
rrYy
rryy
wrinkled/green:
ry
Phenotype Ratio
Round/Yellow:
9
Round/green:
3
1
Summary of Mendel’s
Principles
• Principle of Heredity
– Inheritance of biological
characteristics is determined by
individual units known as genes.
Genes are passed from parents to
offspring.
• Principle of Dominance
– In cases in which two or more
alleles of the gene for a single trait
exist, some gene forms may be
dominant and others recessive.
Summary of Mendel’s
Principles
• Principle of Segregation
– In most sexually reproducing
organisms, each adult has two
copies of each gene- one from each
parent. These genes are
segregated from each other when
gametes are formed.
• Principle of Independent Assortment
– The alleles for different genes
usually segregate independently
from one another.