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Journal 11/17/16 If you recall, humans have 2 of each chromosome - this is how we get dominant and recessive and stuff. What would be different if we naturally had 3 of each chromosome? Or 4? Come up with a guess or an idea. Objective To learn about multiple gene copies in different species Tonight’s Homework p 133:1-4 Research an aneuploidy disease Euploidy We know that humans have 2 of each chromosome. Each chromosome provides a “T” or a “t” allowing us to get combinations like “Tt” for a person. Most of the animals you see and interact with on a daily basis have genes like this. We call creatures like this diploid (2n). But not all are. Some creatures have only 1 of each chromosome. They’re haploid (n). Some have 3 and are triploid (3n). And some even have 4 and are tetraploid (4n). Euploidy Haploid organisms can only have “t” or “T”. Triploid can have things like “tTt”, and tetraploid can have things like “TttT”. So… where do we see this and what does it do? Most species that are diploid have haploid reproductive cells. Example: a cell that’s just “t” from a father combines with one that’s just “T” from a mother, to make a child with “Tt”. We have 2 haploid cells come together to make a new diploid person. Euploidy Some diploid species have the option of reproducing and creating haploid children all by themselves, without a mate. For example, when you eat chicken eggs, you’re eating just what the female has produced. That egg is haploid and just has an “X” chromosome. The egg would need a male to fertilize it to become “XX” or “XY” and actually develop into a chicken. But some creatures can tell that egg to go ahead and turn into a living creature anyways – just one that has only half the genes as normal. This process is called parthogenesis. Euploidy Examples of animals that can do this: Euploidy Triploid organisms only exist in a few plant species. The diagram below shows why. When a triploid cell divides, we end up with cells that have 2 of some chromosomes and 1 of others. This unbalancing is bad because when 2 of these cells come together, we have no guarantee that things will balance out again. They could get worse! So most triploid creatures are sterile (can’t have kids). We artificially create triploid fruit because it’s bigger. Euploidy Tetraploid creatures aren’t super rare in the plant kingdom. Like triploids, though, most tetraploid cells have problems forming gametes. The chromosomes don’t line up and split properly, so most tetraploid plants reproduce by parthogenesis. To have tetraploid plants, we can either have 4 copies of every chromosome (4n), or we can have 2 copies of 2 completely different sets of chromosomes (2n1 + 2n2). This would be like having a human who has full sets of 2 peoples’ DNA! A lot of potatoes and corn are tetraploid. Learning About Aneuploidy Tomorrow we’re going to learn about aneuploidy – genetic problems where a person ends up with a single extra chromosome, or is missing a single chromosome. Your job for homework is to look up one of the following: Down Syndrome Patau Syndrome Turner’s Syndrome Edwards Syndrome Klinefelter Syndrome Trisomy 8 Trisomy 9 For the disorder you pick, you need to find the following information: 1) What chromosome is affected by this disorder? 2) What major problems does it cause? 3) How rare is it? Homework Time You have the rest of class to start in on your homework. p 133:1-4 Exit Question Something that has genes like “GgG” would be… Haploid Diploid Triploid Tetraploid A freak Nonexistent