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Cell cycle reading guide: Chapter 12
1.
Draw a pie chart representing the amount of time spent in each phase of the cell cycle. Include G1, S, G2, mitosis, and
cytokinesis.
2. What are the 3 phases within interphase and what happens during each?
3. Draw a chromosome and label the following: sister chromatids, centromere, kinetochore.
4. Draw and label a cell in each of the following phases of the cell cycle.
Interphase
Prophase
Anaphase
Telophase
5. Define:
Cell plate
G0 phase
Density dependent inhibition
Anchorage dependence
6. What are the functions of kinases and cyclins in regulation of the cell cycle?
7. When does the kinetochore signal for cell division to continue?
8. What are growth factors?
Metaphase
Cytokinesis
9. Write down a four step (1 sentence per step) procedure for doing cell culture to test whether a specific growth factor would affect
fibroblasts.
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10. Define the following terms:
tumor –
benign –
malignant –
metastasis –
cell cycle checkpoint-
11. Page 358-361:
Define:
Oncogene
Tumor suppressor genes
p53 gene
ras gene
Give a brief exlplanation (3-5 sentences) that summarizes how cancer is caused on a molecular level for colorectal cancer (one of
the most common types).
Chapter 13: Using the terms on your objectives sheet, determine which word is being defined.
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______________________ The chromosome pairs during prophase I that are coming together.
______________________ The fertilized egg is also known as this.
______________________ The sperm and egg are collectively called this.
______________________ The cells that are not gametes are called this.
______________________ This is one point on a chromosome indicating the location of a gene.
______________________ A cell that has only one copy of each chromosome.
______________________ These are chromosomes of the same kind, with one coming from each parent.
______________________ The 23rd pair of chromosomes in humans are referred to as _______.
______________________ The process of exchanging pieces of homologous chromosomes during prophase I.
______________________ The X formed by the “legs” of two homologous chromosomes crossing over.
______________________ The type of nuclear division that leads to four copies of haploid cells.
______________________ The process of forming the chiasmata.
______________________ Chromosomes not responsible for determining the sex of an individual.
______________________ The individual copies of a chromosome held together by a centromere.
______________________ The haploid cells that are formed by meiosis of the zygote in fungi.
______________________ The haploid cells that are formed by meiosis in animal cells.
______________________ The plant stage that is composed of diploid cells and can produce spores.